Results 131 to 140 of about 1,076,866 (305)

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Using short-read 16S rRNA sequencing of multiple variable regions to generate high-quality results to a species level

Frontiers in Bioinformatics
IntroductionShort-read amplicon sequencing studies have typically focused on 1-2 variable regions of the 16S rRNA gene. Species-level resolution is limited in these studies, as each variable region enables the characterisation of a different subsection ...
Amy S. Graham, Amy S. Graham, Fadheela Patel, Francesca Little, Andre van der Kouwe, Andre van der Kouwe, Mamadou Kaba, Martha J. Holmes, Martha J. Holmes, Martha J. Holmes, Martha J. Holmes   +10 more
doaj   +1 more source

16S rRNA sequencing of SAR202 bacteria

These data can be used to classify the SAR202 bacteria based on 16S rRNA sequencing.
Changfei He (17801837)
core   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Application of next-generation sequencing (NGS) for disease diagnosis in the beehive

Frontiers in Bee Science
Honey bee (Apis mellifera) populations face increasing threats from pathogens, parasites, and synergistic interactions among pathogens and stressors that contribute to colony losses.
Joerg Mayer
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Experience in Genome Analysis Use in SAET Mobile Complex Facilities

Проблемы особо опасных инфекций, 2014
Described is the first-ever experience in genome analysis use in SAET mobile complex facilities, obtained during the XXVII World-wide Summer Universiade in Kazan, 2013.
E. V. Naidenova, S. A. Portenko, E. S. Kazakova, I. G. Karnaukhov, A. V. Cherkasov, S. A. Shcherbakova, V. V. Kutyrev   +6 more
doaj   +1 more source

Rarefaction curves of high throughput sequencing of 16S rRNA (V2) and 18S rRNA (V9) hypervariable regions.

, 2014
Rarefaction curves of high throughput sequencing of 16S rRNA (V2) and 18S rRNA (V9) hypervariable regions.
Karin Lagesen (234312), Hanne Sogge (421775), Thomas Rohrlack (319199), Xi Xiao (623637), Kjetill S. Jakobsen (45911), Ave Tooming-Klunderud (223315)   +5 more
core   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing.

PLoS ONE, 2019
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons.
Andrew M Smith, Miten Jain, Logan Mulroney, Daniel R Garalde, Mark Akeson   +4 more
doaj   +1 more source