Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Annett Streu +24 more
core +1 more source
Is 17 alpha-hydroxyprogesterone Effective for Preventing Preterm Labor in High Risk Women? [PDF]
OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is 17- alpha hydroxyprogesterone effective for preventing preterm labor in high risk women?”.
Mercado, Hannah E
core +1 more source
17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going? [PDF]
Prematurity is a major public health problem in the United States and worldwide. Women with a history of a previous preterm birth are at high risk for recurrence. Progesterone is a key hormone involved in pregnancy maintenance.
Manuck, T.A.
core +2 more sources
Objective: The objective of the study was to determine the cutoff points (CP) of nine neonatal screening biomarkers performed at the Laboratory of the Center for Neonatal and Genetic Studies in Mexico City, comparing them with the CP recommended by the ...
Luis E. Cobos-Puc +4 more
doaj +1 more source
17-Hydroxyprogesterone caproate to prolong pregnancy after preterm rupture of the membranes: early termination of a double-blind, randomized clinical trial [PDF]
Background Progestational agents may reduce the risk of preterm birth in women with various risk factors. We sought to test the hypothesis that a weekly dose of 17-hydroxyprogesterone caproate (17P) given to women with preterm rupture of the membranes ...
C Andrew Combs +8 more
core +2 more sources
Low dose aspirin in the prevention of recurrent spontaneous preterm labour - the APRIL study: A multicenter randomized placebo controlled trial [PDF]
Background: Preterm birth (birth before 37 weeks of gestation) is a major problem in obstetrics and affects an estimated 15 million pregnancies worldwide annually.
Bekker, M.N. (Mireille) +19 more
core +1 more source
Background Prediction of delivery is important for assessing due dates, providing adequate prenatal care, and suggesting appropriate interventions in preterm and post-term pregnancies.
Lanlan Meng +15 more
doaj +1 more source
Translational Systems Pharmacology Studies in Pregnant Women [PDF]
Pregnancy involves rapid physiological adaptation and complex interplay between mother and fetus. New analytic technologies provide large amounts of genomic, proteomic, and metabolomics data.
Gullapelli, Rakesh +2 more
core +1 more source
N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V. +8 more
core +1 more source
Effects of progestogens in women with preterm premature rupture of membranes [PDF]
Different strategies have been adopted for prevention of spontaneous preterm birth, including use of progestogens. So far, five randomized trials have been published evaluating the efficacy of progestogens in women with PPROM, including a total of 425 ...
DI SARNO, ROSSANA +2 more
core +1 more source

