Results 41 to 50 of about 4,422 (206)

Genetic Susceptibility to Drug Teratogenicity: A Systematic Literature Review

Frontiers in Genetics, 2021
Since the 1960s, drugs have been known to cause teratogenic effects in humans. Such teratogenicity has been postulated to be influenced by genetics. The aim of this review was to provide an overview of the current knowledge on genetic susceptibility to ...
Julia do Amaral Gomes, Julia do Amaral Gomes, Julia do Amaral Gomes, Julia do Amaral Gomes, Emilie Willoch Olstad, Emilie Willoch Olstad, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Thayne Woycinck Kowalski, Kristina Gervin, Kristina Gervin, Kristina Gervin, Fernanda Sales Luiz Vianna, Fernanda Sales Luiz Vianna, Fernanda Sales Luiz Vianna, Fernanda Sales Luiz Vianna, Lavínia Schüler-Faccini, Lavínia Schüler-Faccini, Lavínia Schüler-Faccini, Hedvig Marie Egeland Nordeng, Hedvig Marie Egeland Nordeng, Hedvig Marie Egeland Nordeng   +22 more
doaj   +1 more source

Effect of 17‐alpha hydroxyprogesterone caproate on cervical length in twin pregnancies [PDF]

Ultrasound in Obstetrics & Gynecology, 2012
AbstractObjectivesPrevious studies on singleton pregnancies have indicated that progestogens may reduce the rate of cervical shortening during pregnancy. The aim of this study was to investigate whether treatment with 17‐alpha hydroxyprogesterone caproate (17‐OHPC) has an effect on cervical shortening in twin pregnancies.MethodsThis was a secondary ...
Lim, A., Schuit, E., Papatsonis, D., van Eyck, J., Porath, M., van Oirschot, C., Hummel, P., Hasaart, T., Kleiverda, G., de Graaf, I., van Ginkel, A., Mol, B., Bruinse, H.   +12 more
openaire   +4 more sources

Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis : protocol [PDF]

, 2017
BACKGROUND: Preterm birth is the most common cause of death and harm to newborn babies. Babies that are born early may have difficulties at birth and experience health problems during early childhood.
Alex Hodkinson, Alexis Llewellyn, Kath Wright, Kristina Charlotte Dietz, Lelia Duley, Lesley A. Stewart, Mark Simmonds, Melissa Harden, Ruth Walker, Sahar Sharif, the EPPPIC group   +10 more
core   +2 more sources

A Comparison between the Effects of Vaginal Suppository Progesterone vs. the Injection of 17-Alpha Hydroxyprogesterone Caproate on the Duration of Latent Phase After Controlled Threatened Preterm Labor [PDF]

Journal of Kerman University of Medical Sciences, 2018
Background: Women with preterm labor put in an arrest phase by tocolytic therapy, are at increased risk of recurrent preterm labor. The aim of this study is to evaluate vaginal progesterone suppositories as compared to intramuscular type in order to ...
Fatemeh Mirzaei, samira azimi, Ghazal Mansouri   +2 more
doaj  

Intramuscular 17-hydroxyprogesterone caproate to prevent preterm birth among HIV-infected women in Zambia: study protocol of the IPOP randomized trial

BMC Pregnancy and Childbirth, 2019
Background Each year, an estimated 15 million babies are born preterm, a global burden borne disproportionately by families in lower-income countries. Maternal HIV infection increases a woman’s risk of delivering prematurely, and antiretroviral therapy ...
Joan T. Price, Bellington Vwalika, Bethany L. Freeman, Stephen R. Cole, Helen B. Mulenga, Jennifer Winston, Felistas M. Mbewe, Elwyn Chomba, Lynne M. Mofenson, Dwight J. Rouse, Robert L. Goldenberg, Jeffrey S. A. Stringer   +11 more
doaj   +1 more source

¿La progesterona natural micronizada previene el trabajo de parto pretérmino?: Revisión sistemática de literatura

MedUNAB, 2022
Introducción. La progesterona es una hormona que favorece el mantenimiento del embarazo, es la protagonista de la fisiopatología del trabajo de parto pretérmino.
Villamizar-Jiménez, María Alejandra, Wandurraga-Vargas, Valentina, Vargas-Rey, Javier Enrique, Guarín-Serrano, Rocío   +3 more
doaj   +1 more source

Progesterone Metabolites Produced by Cytochrome P450 3A Modulate Uterine Contractility in a Murine Model [PDF]

, 2015
Objective: We seek to characterize the effect of progesterone metabolites on spontaneous and oxytocin-induced uterine contractility. Study Design: Spontaneous contractility was studied in mouse uterine horns after treatment with progesterone, 2α ...
Grotegut, Chad A., Heine, R. Phillips, Murtha, Amy P., Patil, Avinash S., Swamy, Geeta K., Zheng, Xiaomei   +5 more
core   +1 more source

Nonclassic congenital adrenal hyperplasia misdiagnosed as Turner syndrome

Journal of Human Reproductive Sciences, 2015
We present a patient with nonclassic congenital adrenal hyperplasia (NCAH) misdiagnosed as mosaic Turner syndrome. She presented with complaints of primary infertility. Short stature, the presence of facial hair and hoarse voice was also noted.
Vineet V Mishra, Kumari Pritti, Rohina Aggarwal, Sumesh Choudhary   +3 more
doaj   +1 more source

Progestogens in singleton gestations with preterm prelabor rupture of membranes: a systematic review and metaanalysis of randomized controlled trials [PDF]

, 2018
OBJECTIVE DATA: Preterm prelabor rupture of membranes occurs in 3% of all pregnancies. Neonatal benefit is seen in uninfected women who do not deliver immediately after preterm prelabor rupture of membranes.
Berghella, Vincenzo, Di Sarno, Rossana, Mokhtari, Neggin, Parker, Pamela, Quist-Nelson, Johanna, Saccone, Gabriele   +5 more
core   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source