Results 1 to 10 of about 4,584,770 (187)

Novel 1, 2, 4-Triazoles as Antifungal Agents. [PDF]

open access: yesBiomed Res Int, 2022
The development of innovative antifungal agents is essential. Some fungicidal agents are no longer effective due to resistance development, various side effects, and high toxicity.
Kazeminejad Z   +5 more
europepmc   +2 more sources

Anti-inflammatory and antinociceptive evaluation of newly synthesized 4-(substituted ethanoyl) amino-3-mercapto-5-(4-methoxy) phenyl-1,2,4-triazoles

open access: yesJournal of Pharmacy and Bioallied Sciences, 2011
Introduction: 1,2,4-triazoles and its derivatives have been reported to possess anti-inflammatory, analgesic, antimicrobial, anticancer, antitumor, antitubercular, anticonvulsant, openers of Ca-activated potassium (Maxi-K) channels, antiviral properties,
Neeraj Upmanyu   +3 more
doaj   +2 more sources

Novel Syntheses of Some 1, 2, 4-Triazoles as Potent Bacteriocidal Agents

open access: yesE-Journal of Chemistry, 2010
A facile syntheses of 4-aryl-5-(isomeric pyridoyl)-3H-1, 2, 4-triazoles as potent bacteriocidal agents are described. The newly synthesized compounds were characterized by spectral and elemental analyses.
Ram Janam Singh, Dharmendra Kumar Singh
doaj   +2 more sources

Toxicity prediction of 1,2,4-triazoles compounds by QSTR and interspecies QSTTR models

open access: yesEcotoxicology and Environmental Safety, 2022
1,2,4-triazole derivatives exhibit various biological activities, including antibacterial and antifungal properties. On the other hand, these chemicals may have unique cumulative and harmful effects on living organisms.
Zhiyong Liu   +9 more
doaj   +1 more source

Synthesis of some substituted 1,3,4-oxadiazoles, thiadiazoles and 1,2,4-triazoles [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. Ethyl methacrylate was treated with hydrazine hydrate in ethanol to give the corresponding hydrazide (1).
Shereen R. Mohamed
doaj   +1 more source

Synthesis, antimicrobial and antifungal activity of 3-(2-bromophenyl)-5-(alkylthio)-4-phenyl-4H-1,2,4-triazoles

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
To select a molecule that could become a promising pharmacological agent, chemists use already-known heterocyclic bases by adding pharmacologically active groups. One such heterocyclic system is 1,2,4-triazole base, on the basis of which a huge number of
A. A. Safonov, O. I. Panasenko
doaj   +1 more source

Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles was achieved. 2-(2,3-dimethyl phenyl amino) benzoic acid was esterified to its ethyl ester by its reaction with absolute ethanol in presence of ...
Khalid Daoud   +2 more
doaj   +1 more source

Synthesis of New Bis-1,2,4-Triazole Derivatives

open access: yesMolecules, 2006
A series of new 1,2/1,3-bis[o-(N-methylidenamino-3-aryl-5-phenyl-4H-1,2,4-triazole-4-yl)phenoxy]ethane/propane derivatives 4 were prepared in good yields bytreatment of 4-amino-3-aryl-5-phenyl-4H-1,2,4-triazoles 2 with certain bis-aldehydes 1.Compounds 4
Hakan Bektas, Olcay Bekircan
doaj   +1 more source

Synthesis and Biological evalution of some substituted 2-dibenzyl amino 1,3,4-oxadiazoles , thiadiazoles and 1,2,4-triazoles [PDF]

open access: yesمجلة التربية والعلم, 2013
In this paper the synthesis of some substituted 2-dibenzyl 1,3,4-oxadiazole, thiadiazole and 1,2,4-triazoles derived from dibenzyl amine is reported scheme-1.
Khalid Daoud, Shaima Ismmaeel
doaj   +1 more source

Synthesis and physical-chemical properties of 2-((4-R-3-(morpholinomethylen)-4H-1,2,4-triazole-5yl)thio)acetic acid

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
The creation and improvement of the original domestic medicines is anactual problem of medical and pharmaceutical industries. Chemistry of heterocyclicsystems attracts scientists all over the world, as it is associated with a number of properties of this
R. О. Shcherbyna   +3 more
doaj   +1 more source

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