Results 171 to 180 of about 25,343 (252)

Environmental Circulation of Aspergillus fumigatus With Reduced Susceptibility to Agricultural Triazole in Brazil: Clonal Dissemination of Potentially Resistant Genotypes. [PDF]

Mycoses
de Barros Rodrigues DK, Leeuwerik M, Brankovics B, Fava WS, Venturini J, Meyer W, Arai T, Majima H, Watanabe A, de Souza Carvalho Melhem M.   +9 more
europepmc   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

Deciphering the multidrug resistance paradigm in <i>Candida auris</i>. [PDF]

Antimicrob Agents Chemother
Santana DJ, Cauldron NC, Rogers PD, Cuomo CA.   +3 more
europepmc   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

Global surveillance of <i>Candida albicans</i>: MIC distributions, resistance patterns, and temporal trends from the Antimicrobial Testing Leadership and Surveillance program (2015-2024). [PDF]

Antimicrob Agents Chemother
Cai G, Zhang Z.
europepmc   +1 more source

Accumulation of Histidine Reduce the Susceptibility of Vibrio splendidus Persister Cells to Tetracycline

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Histidine accumulation promotes tetracycline‐induced persister formation in V. splendidus. It enhances membrane potential and upregulating the efflux pump gene, thereby reducing antibiotic susceptibility. ABSTRACT Vibrio splendidus is an opportunistic pathogen widely distributed in marine environments, animal tissues and seabed sediments. It can infect
Yanan Li, Xinnan Pan, Jiayao Chen, Hong Ding, Yina Shao   +4 more
wiley   +1 more source

A Regioselective Synthesis of 2,4-Disubstituted 2<i>H</i>‑1,2,3-Triazoles by Coupling of <i>N</i>‑Tosylhydrazones and Anhydro-Aldose Tosylhydrazones with 4‑Substituted 1<i>H</i>‑1,2,3-Triazoles - Scope and Limitations. [PDF]

ACS Omega
Szakács B, Kaszás T, Juhász-Tóth É, Cservenyák I, Timári I, Nilsson UJ, Varga LA, Docsa T, Molnár V, Kulcsár AE, Márton L, Ábrahám A, Kiss-Szikszai A, József J, Juhász L, Somsák L, Tóth M.   +16 more
europepmc   +1 more source

Reaction Enumeration Based on NBO‐Informed Molecular Graphs

Journal of Computational Chemistry, Volume 47, Issue 19, 15 July 2026.
NBO‐informed molecular graphs represent chemistry via valence orbitals rather than atomic connectivity, enabling consistent reaction analysis across environments. By identifying delocalized motifs and increasing complexity adaptively, the framework enables efficient exploration of inaccessible mechanisms and diverse catalytic and reaction networks for ...
Javier E. Alfonso‐Ramos, Thijs Stuyver
wiley   +1 more source

Triazoles Versus Echinocandins for the First-Line Treatment of Invasive Pulmonary Aspergillosis: A Propensity Score-Weighted Multicenter Study. [PDF]

Open Forum Infect Dis
Hatzl S, Geiger C, Kriegl L, Reinisch A, Keldorfer M, Wölfler A, Wallner M, von Lewinski D, Eller P, Krause R.   +9 more
europepmc   +1 more source

Oligonucleotides Post‐Synthetic Modifications: An Overview of Clickable Nucleoside Phosphoramidites Suitable for Solid‐Phase Synthesis

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne, Alexandra Bristiel, Dominique Urban, Dominique Guianvarc’h   +3 more
wiley   +1 more source