Results 41 to 50 of about 38,585 (330)

Synthesis of ylidene derivatives of 4-amino-5-(4-tert-butylphenyl)-4H-1,2,4-triazole-3-thiol

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, alprazolam, letrozole and others) in the practice.
I. I. Aksionova, O. I. Panasenko, E. G. Knysh   +2 more
doaj   +1 more source

Deprotometalation-iodolysis and computed CH acidity of 1,2,3- and 1,2,4-triazoles. Application to the synthesis of resveratrol analogues

, 2015
International audience1-Aryl- and 2-aryl-1,2,3-triazoles were synthesized by N-arylation of the corresponding azoles using aryl iodides. The deprotometalations of 1-phenyl-1,2,3-triazole and -1,2,4-triazole were performed using a 2,2,6,6 ...
Bentabed-Ababsa, Ghenia, Chevallier, Floris, Duval, Raphaël E., Fontanay, Stéphane, Halauko, Yury S., Ivashkevich, Oleg A., Matulis, Vadim E., Mongin, Florence, Nagaradja, Elisabeth, Phillipot, Stéphanie, Roisnel, Thierry, Scalabrini, Mathieu   +11 more
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Copper(I)-Phosphinite Complexes in Click Cycloadditions: Three-Component Reactions and Preparation of 5-Iodotriazoles [PDF]

, 2016
© 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one-pot azidonation/cycloaddition of
Crosbie, P, Diez-Gonzalez, S, Lal, S, Perez, J   +3 more
core   +2 more sources

Discussion of antimicrobial and antifungal activity of 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Studying new biologically active substances nowadays become increasingly important. The current range of the pharmaceutical market requires constant updating of domestic products.
T. V. Kravchenko, O. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +1 more source

Regioselective Synthesis of New Family of 2-Substituted 1,2,3-Triazoles and Study of Their Fluorescent Properties

Molecules, 2023
Modification of 5-aryl-4-trifluoroacetyltriazoles at the NH-moiety was investigated. Screening of the alkylation conditions revealed that using Na2CO3 as a base and DMF as a solvent of 2-substituted triazoles can be preferentially prepared in up to 86 ...
Vasiliy M. Muzalevskiy, Zoia A. Sizova, Valentine G. Nenajdenko   +2 more
doaj   +1 more source

Synthesis, Evaluation and Characterization of Some 1,3,4-Triazole-2-one Derivatives as Antimicrobial Agents

E-Journal of Chemistry, 2012
A series of novel compounds like 3[(phenyl substituted)-5-methyl-1(Benzosulphonylamine)]-1,3,4-triazole-2-ones II(a-f) were synthesized by treating 4-amino-1-phenyl-3-methyl-5-oxo-1,2,4-triazoles with benzene sulphonyl chloride using pyridine as solvent.
Mahabaleshwaraiah Neelgundmath, Oblennavar Kotresh   +1 more
doaj   +1 more source

Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents [PDF]

, 2019
A series of cationic chlorido arene-iridium(III) and arene-osmium(II) complexes with bidentate pyridyl functionalized mesoionic carbenes (MIC) of the 1,2,3-triazol-5-ylidene type have been prepared.
Bolje, Aljoša, Brozović, Anamaria, Gržan, Tena, Hohloch, Stephan, Košmrlj, Janez, Kralj, Juran, Osmak, Maja, Sarkar, Biprajit, Steiner, Ivana, Stojanović, Nikolina, Stupin Polančec, Darija, Tupek, Ana, Urankar, Damijana   +12 more
core   +1 more source

1, 3-Dipolar Cycloaddition (Part I): Synthesis of 1, 2, 3-Triazole Derivatives in Nucleoside Chemistry [PDF]

, 2015
Bakrom katalizirana Huisgenova 1, 3-dipolarna cikloadicija azida i terminalnih alkina kojom regioselektivno nastaju 1, 4-disupstituirani 1, 2, 3-triazoli često je primjenjivana metoda sintetske organske kemije.
Bajić, Miroslav, Krstulović, Luka, Saftić, Dijana, Žinić, Biserka   +3 more
core   +2 more sources

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles

Molecules, 2001
A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans.
Aleksandra Buzarovska, Dora Gabor Molnar, Vlado Kakurinov, Vesna Dimova, Katica Colanceska-Ragenovic   +4 more
doaj   +1 more source

Benzotriazole is antiestrogenic in vitro but not in vivo [PDF]

, 2007
Copyright © 2007 SETAC. This is the accepted version of the following article: Harris et al (2007), "Benzotriazole is antiestrogenic in vitro but not in vivo", Environmental Toxicology and Chemistry, 26(11), 2367–2372, which has been published in final ...
Brian, JV, Giger, W, Harris, CA, Routledge, EJ, Schaffner, C, Sumpter, JP   +5 more
core   +1 more source