Scientia Pharmaceutica, 2019 According to our quantum and chemical calculations 4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acid imidazolide is theoretically almost as reactive as its 2-carbonyl analog, and it forms the corresponding N-pyridyl-4-methyl-2,2-dioxo-1H-2&
Igor V. Ukrainets +8 more
doaj +1 more source
Синтез та біологічна активність трифторометилзаміщених анілідів 4-гідрокси-2,2-діоксо-1Н-2λ6,1-бензотіазин-3-карбонових кислот [PDF]
, 2015 In order to reveal the regularities of the “structure – biological activity” relationship by interaction of esters of 1-R-4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazin-3-carboxylic acids and trifluoromethyl substituted anilines in boiling xylene with good ...
Dzyubenko, S. P. +3 more
core +2 more sources
4-[2-(Anthracen-9-ylmethylidene)hydrazinylidene]-3-chloro-1-methyl-3,4-dihydro-1H-2λ6,1-benzothiazine-2,2-dione [PDF]
, 2012 In the title compound, C24H18ClN3O2S, the dihedral angle between the benzene ring and the anthracene ring system is 41.10 (8)°. The thiazine ring has a half-chair conformation and the Cl atom is in an axial orientation.
Asghar, Muhammad Nadeem +4 more
core +3 more sources
(R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile [PDF]
Molbank, 2014 Copper-catalyzed cross-coupling between (S)-S-methyl-S-phenylsulfoximine (1) and 2-iodobenzonitrile (2) resulted in the discovery of an unprecedented one-pot triple arylation sequence to give (R)-(−)-2-[(5-oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin- 12-yl)amino]benzonitrile (4).
Frings, Marcus +2 more
openaire +3 more sources
Синтез і дослідження антиоксидантної та протизапальної активності моно- та біс-похідних спіро-2-оксіндол[3,3']піролу [PDF]
, 2018 Aim. To synthesize range of mono- and bis-derivatives of spiro-2-oxindole[3,3']pyrrole and to study antioxidant and antiinflammatory activity of the obtained compounds.Materials and methods.
Chernykh, V. P. +3 more
core +2 more sources
Journal of Heterocyclic Chemistry, Volume 62, Issue 9, Page 938-943, September 2025.Through an efficient solid‐phase synthesis method, 32 different 1,3,5,6‐tetra‐substituted 3,5‐dihydroimidazo[4,5‐c][1,2]thiazin‐4(1H)‐one 2,2‐dioxide derivatives were synthesized. The derivative library, with a total of four diversities, showed an overall yield of 7%–32% over 8 steps.
Jimin Moon +3 more
wiley +1 more source
Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos [PDF]
, 2019 Aedes aegypti (Linnaeus, 1762; Diptera: Culicidae) is the main vector transmitting viral diseases such as dengue fever, dengue haemorrhagic fever, urban yellow fever, zika and chikungunya. Worldwide, especially in the Americas and Brazil, many cases of
Campos Rosa, Joaquín María +1 more
core +2 more sources
The molecular virology of coronaviruses [PDF]
, 2020 Few human pathogens have been the focus of as much concentrated worldwide attention as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19.
Glaunsinger, Britt A +5 more
core +1 more source
Использование алифатических альдегидов в синтезе новых 1Н-2,1-бензотиазин-4-он 2,2-диоксидов, конденсированных с пирановым ядром с помощью домино-реакций. Антимикробная активность синтезированных соединений [PDF]
, 2016 Domino-type Knoevenagel-Michael-hetero-Thorpe-Ziegler and Knoevenagel-hetero-Diels-Alder interactions using 1-ethyl-1Н-2,1-benzothiazin-4(3Н)-one 2,2-dioxide and aliphatic aldehydes as initial compounds have been studied.
Chernykh, V. P. +14 more
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Triagem virtual de potenciais inibidores para a proteína NS5 de Dengue vírus sorotipo 3 [PDF]
, 2021 Trabalho de Conclusão de Curso (Graduação)A dengue é uma doença que se tornou uma grande preocupação para a saúde pública e, de acordo com a OPAS (Organização Pan-Americana de Saúde), nas últimas décadas, a incidência global da enfermidade aumentou ...
Sivieri, Vitória Juliane de Aquino
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