Scientia Pharmaceutica, 2019 According to our quantum and chemical calculations 4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acid imidazolide is theoretically almost as reactive as its 2-carbonyl analog, and it forms the corresponding N-pyridyl-4-methyl-2,2-dioxo-1H-2&
Igor V. Ukrainets +8 more
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Journal of Heterocyclic Chemistry, Volume 62, Issue 9, Page 938-943, September 2025.Through an efficient solid‐phase synthesis method, 32 different 1,3,5,6‐tetra‐substituted 3,5‐dihydroimidazo[4,5‐c][1,2]thiazin‐4(1H)‐one 2,2‐dioxide derivatives were synthesized. The derivative library, with a total of four diversities, showed an overall yield of 7%–32% over 8 steps.
Jimin Moon +3 more
wiley +1 more source
Synthesis of fluorescent 7-amino-2,1-benzothiazines and total synthesis of buddledone A [PDF]
, 2018 Title from PDF of title page (University of Missouri--Columbia, viewed on May 31, 2012). ; The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. ; Dissertation advisor: Dr. Michael Harmata ; Vita. ; Ph. D.
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(R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile [PDF]
Molbank, 2014 Copper-catalyzed cross-coupling between (S)-S-methyl-S-phenylsulfoximine (1) and 2-iodobenzonitrile (2) resulted in the discovery of an unprecedented one-pot triple arylation sequence to give (R)-(−)-2-[(5-oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin- 12-yl)amino]benzonitrile (4).
Frings, Marcus +2 more
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Studies of the chemistry of Tröger's base, cyclopentadienones, and 2,1-benzothiazines
, 2018 The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.
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Chemistry of Heterocyclic Compounds, 2017 4,6-Dihydropyrano[3,2-c][2,1]benzothiazine 5,5-dioxides were synthesized via three-component interaction of 1-ethyl-1H-2,1-benzothiazin-4(3H)-one 2,2-dioxide with active methylene nitriles and cycloalkanecarbaldehydes. The latter were also applied to obtain ammonium salts of 3,3'-(cycloalkylmethanediyl)bis(1-ethyl-1H-2,1-benzothiazin-4-ol) 2,2,2',2 ...
Dmitry A. Lega +4 more
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Seeking heterocyclic scaffolds as antivirals against dengue virus. [PDF]
Eur J Med Chem, 2022 De S +5 more
europepmc +1 more source
Naphthopyran molecular switches and their emergent mechanochemical reactivity. [PDF]
Chem Sci, 2023 McFadden ME +3 more
europepmc +1 more source
Novel quinoline/thiazinan-4-one hybrids; design, synthesis, and molecular docking studies as potential anti-bacterial candidates against MRSA. [PDF]
RSC Adv, 2023 Mohamed AH +7 more
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Phytochemical-Stabilized Platinum-Decorated Silver Nanocubes INHIBIT Adenocarcinoma Cells and Enhance Antioxidant Effects by Promoting Apoptosis via Cell Cycle Arrest. [PDF]
Pharmaceutics, 2022 Oladipo AO +3 more
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