Results 21 to 30 of about 190 (131)

(3S,4Z)-3-Chloro-1-methyl-4-[(2E)-(3-methylbenzylidene)hydrazinylidene]-3,4-dihydro-1H-2,1-benzothiazine 2,2-dioxide

Acta Crystallographica Section E, 2012
In the title compound, C17H16ClN3O2S, the dihedral angle between the benzene rings is 7.75 (13)°. The thiazine ring adopts an envelope conformation with the S atom as the flap at a distance of 0.813 (2) &#197 ...
Muhammad Shafiq, M. Nawaz Tahir, Islam Ullah Khan, Muhammad Zia-Ur-Rehman   +3 more
doaj   +1 more source

Molecular and crystal structure of 5,9-dimethyl-5H-pyrano[3,2-c:5,6-c′]bis[2,1-benzothiazin]-7(9H)-one 6,6,8,8-tetroxide dimethylformamide monosolvate

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title molecule crystallizes as a dimethylformamide monosolvate, C19H14N2O6S2·C3H7NO. The molecule was expected to adopt mirror symmetry but slightly different conformational characteristics of the condensed benzothiazine ring lead to point group ...
Andrii Rybalka, Svitlana Shishkina, Igor Ukrainets, Lyudmila Sidorenko, Galina Sim   +4 more
doaj   +1 more source

Benzo[1,5]thiazepine: Synthesis, Reactions, Spectroscopy, and Applications

Organic Chemistry International, Volume 2013, Issue 1, 2013., 2013
This review article deals with synthesis and reactions of benzo[1,5]thiazepines and the related derivatives and their applications, biological activity as well as spectroscopic data. Most of the reported data on the methods of synthesis, chemical reactions, and biological activity of these heterocycles published over the last ten years are reviewed in ...
Khairy A. M. El-Bayouki, William Setzer
wiley   +1 more source

2,1-Benzothiazines : preparation and reactivity [PDF]

, 2018
Title from PDF of title page (University of Missouri--Columbia, viewed on May 24, 2010). ; The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. ; Dissertation advisor: Dr. Michael Harmata. ; Vita. ; Ph. D. University of Missouri--
openaire   +2 more sources

1-Ethyl-1H-2,1-benzothiazin-4(3H)-one 2,2-dioxide

Acta Crystallographica Section E, 2008
In the title compound, C10H11NO3S, there is distorted tetrahedral geometry around the S atom. The heterocyclic thiazine ring adopts a half-chair conformation. The ethyl and sulfonyl groups form dihedral angles of 82.53 (13) and 88.91 (9)°
Waseeq Ahmad Siddiqui, M. Nawaz Tahir, Islam Ullah Khan, Muhammad Shafiq   +3 more
doaj   +1 more source

SYNTHESIS OF NOVEL ANTI-BACTERIAL 2,1-BENZOTHIAZINE 2,2-DIOXIDES DERIVED FROM METHYL ANTHRANILATE [PDF]

Journal of the Chilean Chemical Society, 2011
A convenient ultrasound assisted synthesis of new anti-bacterial N-benzylidene-N’-(1-methyl-2, 2-dioxo-2,3-dihydro-1H-2λ6-benzo[c][1,2]thiazin-4-ylidene)hydrazines from methyl anthranilate is reported. Methyl anthranilate was reacted with methane sulfonyl chloride, followed by N-alkylation and subsequent base catalyzed cyclization.
SHAFIQ, MUHAMMAD, ZIA-UR-REHMAN, MUHAMMAD, ULLAH KHAN, ISLAM, NADEEM ARSHAD, MUHAMMAD, AHMED KHAN, SIRAJ   +4 more
openaire   +2 more sources

(R,S)-2′-Amino-6′-methyl-2,5′,5′-trioxo-6′H-spiro[indoline-3,4′-pyrano[3,2-c][2,1]benzothiazine]-3′-carbonitrile dimethylformamide monosolvate

Acta Crystallographica Section E, 2014
The title solvate, C20H14N4O4S·C3H7NO, comprises a stereogenic centre but the centrosymmetric space group causes the presence of the racemate in the crystal. The spiro-joined fragments are almost orthogonal, with a dihedral angle of 86.8 (2)° between the
Svitlana V. Shishkina, Igor V. Ukrainets, Lidiya A. Petrushova   +2 more
doaj   +1 more source

The Crystal Structure of N-(1-Arylethyl)-4-methyl- 2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxamides as the Factor Determining Biological Activity Thereof

Scientia Pharmaceutica, 2019
In order to detect new structural and biological patterns in a series of hetaryl-3-carboxylic acid derivatives, the optically pure (S)- and (R)-enantiomers of N-(1-arylethyl)-4-methyl- 2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides, their true ...
Igor V. Ukrainets, Ganna M. Hamza, Anna A. Burian, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Irina A. Danylova, Galina Sim   +7 more
doaj   +1 more source

N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines [PDF]

Arkivoc, 2011
The synthesis of 4-alkoxy-1H-2,1-benzothiazine 2,2-dioxide derivatives was achieved through an unexpected base-mediated cyclization of N-benzoyl-N-methylsulfonylanthranilates. A reaction mechanism involving the sulfene species has been postulated.
MANFRONI, GIUSEPPE, MESCHINI, FRANCESCO, COSTANTINO, FERDINANDO, TABARRINI, Oriana, CECCHETTI, Violetta   +4 more
openaire   +2 more sources

Molecular Conformations and Biological Activity of N-Hetaryl(aryl)alkyl-4-methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxamides

Scientia Pharmaceutica, 2018
The analysis of our previous studies on the search for synthetic analgesics among N-R-amides of bicyclic hetaryl-3-carboxylic acids has been performed; on its basis N-hetaryl(aryl)-alkyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides have ...
Igor V. Ukrainets, Ganna M. Hamza, Anna A. Burian, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Lina A. Grinevich, Vasyl V. Grynenko, Galina Sim   +8 more
doaj   +1 more source