Results 91 to 100 of about 18,161,920 (183)

Temperature Dependence of the Complexation Mechanism of Celecoxib and Hydroxyl-β-cyclodextrin in Aqueous Solution

Pharmaceutics, 2014
Hydroxypropyl-β-cyclodextrin (HP-β-CD) is commonly used as a complexation reagent to solubilize compounds with poor aqueous solubility to improve in vivo dosing. However, the degree of solubility enhancement was often limited by the formation of only a 1:
Po-Chiang Chiang, Yue Shi, Yong Cui
doaj   +1 more source

Enhanced stability of sulfamethoxazole and trimethoprim against oxidation using hydroxypropyl-B-cyclodextrin

, 2005
The effect of hydroxypropyl-β-cyclodextrin (HPβCD) on the chemical stability of sulfamethoxazole and trimethoprim (co-trimoxazole) under oxidation stress at 50 ± 2 °C was investigated.
Glenn Jacobson (14740078), Pourmokhtar, M (15504083)   +1 more
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The development of an innovative method to improve the dissolution performance of rivaroxaban

Heliyon
Recent advancements in the formulation of solid dosage forms involving active ingredient-cyclodextrin complexes have garnered considerable attention in pharmaceutical research. While previous studies predominantly focused on incorporating these complexes
Emma Adriana Ozon, Erand Mati, Oana Karampelas, Valentina Anuta, Iulian Sarbu, Adina Magdalena Musuc, Raul-Augustin Mitran, Daniela C. Culita, Irina Atkinson, Mihai Anastasescu, Dumitru Lupuliasa, Mirela Adriana Mitu   +11 more
doaj   +1 more source

A thorough analysis of the effect of surfactant/s on the solubility and pharmacokinetics of (S)-zaltoprofen

Asian Journal of Pharmaceutical Sciences, 2019
Until now, there are no publications about the preformulation studies on (S)-zaltoprofen ((S)-ZPF). Hence, we first investigated the solubility of (S)-ZPF, screened solubilizers and performed the pharmacokinetic study of (S)-ZPF in the presence of the ...
Cuong Viet Pham, Jong-Suep Baek, Jong-Hun Park, Sang-Hun Jung, Jong-Seong Kang, Cheong-Weon Cho   +5 more
doaj   +1 more source

Change in the Kinetic Regime of Aggregation of Yeast Alcohol Dehydrogenase in the Presence of 2-Hydroxypropyl-β-cyclodextrin. [PDF]

Int J Mol Sci, 2023
Borzova VA, Chernikov AM, Mikhaylova VV, Kurganov BI.   +3 more
europepmc   +1 more source

Emprego de estratégias para a melhoria das propriedades biofarmacêuticas da hidroclorotiazida e norfloxacino: formação de complexos de inclusão com ciclodextrinas [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis ...
Mendes, Cassiana
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In Vitro Wound Healing Potential of a Fibroin Film Incorporating a Cannabidiol/2-Hydroxypropyl-β-cyclodextrin Complex. [PDF]

Pharmaceutics, 2023
Klinsang T, Charoensit P, Phimnuan P, Luangpraditkun K, Ross GM, Viennet C, Ross S, Viyoch J.   +7 more
europepmc   +1 more source

Preparation and characterization of artemether inclusion complexes with hydroxypropyl-β-cyclodextrin

, 2017
Purpose: To investigate experimentally the inclusion of artemether into the cavity of  hydroxypropyl-β-cyclodextrin and examine its effect on the solubility and dissolution rate of the drug.Methods: Inclusion complexes of artemether with hydroxypropyl-β ...
Yahaya, Zwanden Sule, Ofokansi, Kenneth C., Bhatia, Pat G., Allagh, Suzane T.   +3 more
core   +1 more source

2-Hydroxypropyl-β-cyclodextrin (HPβCD) as a Potential Therapeutic Agent for Breast Cancer. [PDF]

Cancers (Basel), 2023
Saha ST, Abdulla N, Zininga T, Shonhai A, Wadee R, Kaur M.   +5 more
europepmc   +1 more source

The Application of Microwave Heating Methods in Pharmaceutical Formulations

This study investigated the potential application of formulating pharmaceutical products using microwave heating methods alongside associated analytical investigations.
Bedford, Susan
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