Results 131 to 140 of about 26,508 (195)

Pharmacokinetic studies of hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex and ameliorated DSS-induced colitis in mice. [PDF]

Biosci Rep, 2023
Su J, Zhang X, Cao S, Liu C, Fu X, Zhang R, Li X, Xue J, Li Y, Wang X, Ding Y, Li Y, Chu X.   +12 more
europepmc   +1 more source

2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis. [PDF]

J Lipid Res, 2023
El-Darzi N, Mast N, Hammer SS, Dorweiler TF, Busik JV, Pikuleva IA.   +5 more
europepmc   +1 more source

Molecular Interaction and Solubilization Efficiency of Neohesperidin in Ternary Systems with Hydroxypropyl-β-cyclodextrin and Meglumine

Foods
The solubilization of poorly water-soluble natural bioactive compounds remains a significant challenge. This study aims to design a ternary inclusion system to enhance the solubility of the poorly water-soluble compound Neohesperidin (NH).
Na Xia, Yanquan Liu, Dan Gao, Siming Zhu
doaj   +1 more source

Cyclodextrin-based polyrotaxanes: Cellular uptake enhancement effect of different functionality types

Carbohydrate Polymer Technologies and Applications
Four polyisoprene-based polyrotaxanes (PRX) were synthesized via rotaxa-polymerization and subsequent modification using randomly methylated β-cyclodextrin (RAMEB), hydroxypropyl β-cyclodextrin (HP-βCD), thiolated (HP-βCD-SH), and mercaptosuccinic HP-βCD
David Gintsburg, Pia Kreuzer, Khush Bakhat Afzal, Ilaria Polidori, Martyna Truszkowska, Anna Seybold, Andreas Bernkop-Schnürch, Gergely Kali   +7 more
doaj   +1 more source

Inclusion Complex between Local Anesthetic/2-hydroxypropyl-β-cyclodextrin in Stealth Liposome. [PDF]

Molecules, 2022
Souza GK, Gallo A, Novicki LH, Neto HR, de Paula E, Marsaioli AJ, Cabeça LF.   +6 more
europepmc   +1 more source

Dopamine D3 Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats. [PDF]

, 2019
Prescription opioids, such as oxycodone, are highly effective analgesics for clinical pain management, but approximately 25% of patients who are prescribed opioids misuse them, and 5%-10% develop an opioid use disorder (OUD).
de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Newman, Amy H, Sedighim, Sharona   +4 more
core  

Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1-2 trial.

The Lancet, 2017
D. Ory, E. Ottinger, N. Farhat, K. King, Xuntian Jiang, L. Weissfeld, E. Berry-Kravis, Cristin D. Davidson, S. Bianconi, Lee Ann Keener, R. Rao, A. Soldatos, Rohini Sidhu, Kimberly A. Walters, Xin Xu, A. Thurm, B. Solomon, W. Pavan, B. N. Machielse, Mark L. Kao, S. Silber, J. McKew, C. Brewer, C. Vite, S. Walkley, C. Austin, F. Porter   +26 more
semanticscholar   +1 more source

Avibactam–Cyclodextrin Inclusion Complexes: Computational and Thermodynamic Insights for Drug Delivery, Detection, and Environmental Scavenging

Molecules
The escalating crisis of multidrug resistance, together with the persistence of antibiotic residues in clinical and environmental matrices, demands integrated strategies that couple sensitive detection, efficient decontamination, and controlled delivery.
Jackson J. Alcázar, Paola R. Campodónico, René López   +2 more
doaj   +1 more source

Synthesis of the Supramolecular Structure of Vanadium Pentoxide Nanoparticles with Native and Modified β-Cyclodextrins for Antimicrobial Performance

Bioengineering
Cyclodextrins in metal oxide nanoparticles (NPs) serve as stabilizing, dispersing, and functionalizing agents that enhance antimicrobial performance through better nanoparticle stability, synergistic action, and potential controlled release mechanisms ...
Rajaram Rajamohan, Kanagaraj Thamaraiselvi, Chaitany Jayprakash Raorane, Kuppusamy Murugavel, Chandramohan Govindasamy, Seong-Cheol Kim, Seho Sun   +6 more
doaj   +1 more source

Enhancement of Dissolving Capacity and Reducing Gastric Mucosa Irritation by Complex Formation of Resibufogenin with β-Cyclodextrin or 2-Hydroxypropyl-β-cyclodextrin. [PDF]

Molecules, 2022
Liu N, Chen HP, Yang ZM, Xia MY, Wang D, Zang LH, Liu DC.   +6 more
europepmc   +1 more source