Results 61 to 70 of about 9,813 (135)

The development of an innovative method to improve the dissolution performance of rivaroxaban

Heliyon
Recent advancements in the formulation of solid dosage forms involving active ingredient-cyclodextrin complexes have garnered considerable attention in pharmaceutical research. While previous studies predominantly focused on incorporating these complexes
Emma Adriana Ozon, Erand Mati, Oana Karampelas, Valentina Anuta, Iulian Sarbu, Adina Magdalena Musuc, Raul-Augustin Mitran, Daniela C. Culita, Irina Atkinson, Mihai Anastasescu, Dumitru Lupuliasa, Mirela Adriana Mitu   +11 more
doaj   +1 more source

Change in the Kinetic Regime of Aggregation of Yeast Alcohol Dehydrogenase in the Presence of 2-Hydroxypropyl-β-cyclodextrin. [PDF]

Int J Mol Sci, 2023
Borzova VA, Chernikov AM, Mikhaylova VV, Kurganov BI.   +3 more
europepmc   +1 more source

A thorough analysis of the effect of surfactant/s on the solubility and pharmacokinetics of (S)-zaltoprofen

Asian Journal of Pharmaceutical Sciences, 2019
Until now, there are no publications about the preformulation studies on (S)-zaltoprofen ((S)-ZPF). Hence, we first investigated the solubility of (S)-ZPF, screened solubilizers and performed the pharmacokinetic study of (S)-ZPF in the presence of the ...
Cuong Viet Pham, Jong-Suep Baek, Jong-Hun Park, Sang-Hun Jung, Jong-Seong Kang, Cheong-Weon Cho   +5 more
doaj   +1 more source

In Vitro Wound Healing Potential of a Fibroin Film Incorporating a Cannabidiol/2-Hydroxypropyl-β-cyclodextrin Complex. [PDF]

Pharmaceutics, 2023
Klinsang T, Charoensit P, Phimnuan P, Luangpraditkun K, Ross GM, Viennet C, Ross S, Viyoch J.   +7 more
europepmc   +1 more source

2-Hydroxypropyl-β-cyclodextrin (HPβCD) as a Potential Therapeutic Agent for Breast Cancer. [PDF]

Cancers (Basel), 2023
Saha ST, Abdulla N, Zininga T, Shonhai A, Wadee R, Kaur M.   +5 more
europepmc   +1 more source

Physicochemical Characterization and Cyclodextrin Complexation of the Anticancer Drug Lapatinib

Journal of Chemistry, 2017
Lapatinib (LAP), the tyrosine kinase inhibitor drug with moderate bioavailability, was characterized in terms of physicochemical properties: acid-base characteristics, lipophilicity, and solubility.
Gergő Tóth, Ádám Jánoska, Gergely Völgyi, Zoltán-István Szabó, Gábor Orgován, Arash Mirzahosseini, Béla Noszál   +6 more
doaj   +1 more source

2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques. [PDF]

J Virol, 2023
Ortiz AM, Castello Casta F, Rahmberg A, Markowitz TE, Brooks K, Simpson J, Brenchley JM.   +6 more
europepmc   +1 more source

Characteristics of physical and chemical properties, antioxidant, antimutagenic and reparative activity of nanocomplexes of curcuminoids with cyclodextrins

Современная наука и инновации
The spectral properties and thermal stability of cyclodextrins:curcuminoids nanocomplexes were characterized by the use of the methods of IR spectroscopy and thermal analysis.
M. A. Kapustin, A. S. Chubarova, I. V. Rzhepakovsky, S. I. Piskov, I. A. Evdokimov, A. D. Lodygin, V. G. Cigankov, N. V. Dudchik, A. V. Adamovich, V. P. Kurchenko   +9 more
doaj   +1 more source

The Formulation of Curcumin: 2-Hydroxypropyl-β-cyclodextrin Complex with Smart Hydrogel for Prolonged Release of Curcumin. [PDF]

Pharmaceutics, 2023
Nikolić L, Urošević M, Nikolić V, Gajić I, Dinić A, Miljković V, Rakić S, Đokić S, Kesić J, Ilić-Stojanović S, Nikolić G.   +10 more
europepmc   +1 more source

Binary and Ternary Inclusion Complexes of Niflumic Acid: Synthesis, Characterization, and Dissolution Profile

Pharmaceutics
Although niflumic acid (NA) is one of the most used non-steroidal anti-inflammatory drugs, it suffers from poor solubility, low bioavailability, and significant adverse effects. To address these limitations, the complexation of NA with cyclodextrins (CDs)
Zohra Bouchekhou, Amel Hadj Ziane-Zafour, Florentina Geanina Lupascu, Bianca-Ștefania Profire, Alina Nicolescu, Denisse-Iulia Bostiog, Florica Doroftei, Ioan-Andrei Dascalu, Cristian-Dragoș Varganici, Mariana Pinteala, Lenuta Profire, Tudor Pinteala, Bachir Bouzid   +12 more
doaj   +1 more source