Results 11 to 20 of about 10,839 (246)

Dichlorido[1-(1,10-phenanthrolin-2-yl)-2-pyridone]copper(II)

open access: goldActa Crystallographica Section E, 2008
In the title mononuclear complex, [CuCl2(C17H11N3O)], the CuII ion is in a distorted square-pyramidal coordination environment. The crystal structure is stabilized by various π–π stacking interactions in which the benzene ring, a pyridine
Jin Min Li
doaj   +2 more sources

Salivary N1-Methyl-2-Pyridone-5-Carboxamide, a Biomarker for Uranium Uptake, in Kuwaiti Children Exhibiting Exceptional Weight Gain. [PDF]

open access: goldFront Endocrinol (Lausanne), 2019
Goodson JM   +10 more
europepmc   +3 more sources

Optimization of 4-Amino-2-Pyridone Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9: Integrating Structure-Activity and Structure-Metabolism Relationships. [PDF]

open access: yesChemMedChem
Green chemistry‐based late‐stage functionalization (LSF) of the anti‐proprotein convertase subtilisin/kexin type 9 (PCSK9) early lead compound 5c led to optimized analogs with improved metabolic stability/PCSK9 IC50 ratio. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key drug target for the treatment of different hypercholesterolemia ...
Giannessi L   +12 more
europepmc   +2 more sources

Synthesis and characterization of Cu and Fe (1:2) metal complexes based on their substituted pyridones acid dyes and their application on wool fabrics [PDF]

open access: yesJournal of Chemistry Letters, 2022
In this study, the investigation deals with synthesis of acid dyes from 4-amino-1-(4-sulfophenyl)- 3-methyl-5-pyrazolone and their pyridone derivatives and their metal complexes (Cu (II)and Fe (II)).
Olamide Ajani   +2 more
doaj   +1 more source

Azo-hydrazone tautomerism of aryl azo pyridone dyes [PDF]

open access: yesHemijska Industrija, 2013
In the last three or four decades disperse dyes derived from pyridones (in particular azo pyridone dyes) have gained in importance, and are widely used in various fields.
Mirković Jelena M.   +3 more
doaj   +1 more source

Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection

open access: yesJournal of Genetic Engineering and Biotechnology, 2023
Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail   +8 more
doaj   +1 more source

Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana   +3 more
doaj   +1 more source

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