Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds [PDF]
Hemijska Industrija, 2014 2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications.
Mijin Dušan Ž. +3 more
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Diversity-oriented functionalization of 2-pyridones and uracils [PDF]
Nature Communications, 2021 Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of ...
Yong Shang +8 more
doaj +4 more sources
Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones [PDF]
Molecules, 2012 Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao +9 more
doaj +2 more sources
Synthesis and characterization of Cu and Fe (1:2) metal complexes based on their substituted pyridones acid dyes and their application on wool fabrics [PDF]
Journal of Chemistry Letters, 2022 In this study, the investigation deals with synthesis of acid dyes from 4-amino-1-(4-sulfophenyl)- 3-methyl-5-pyrazolone and their pyridone derivatives and their metal complexes (Cu (II)and Fe (II)).
Olamide Ajani +2 more
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Solid-Phase Synthesis of Diverse Macrocycles by Regiospecific 2‑Pyridone Formation: Scope and Applications [PDF]
JACS AuSkander A. Abboud, Thomas Kodadek
doaj +2 more sources
Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones [PDF]
ChemInform, 2016 Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di- and (3,4,5-tri)-halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (copper-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.
Gallagher, Timothy, Honraedt, Aurelien
core +7 more sources
Azo-hydrazone tautomerism of aryl azo pyridone dyes [PDF]
Hemijska Industrija, 2013 In the last three or four decades disperse dyes derived from pyridones (in particular azo pyridone dyes) have gained in importance, and are widely used in various fields.
Mirković Jelena M. +3 more
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CXXXI.—Benzeneazo-2-pyridone [PDF]
J. Chem. Soc., Trans., 1908 n ...
Mills, William Hobson, Widdows, Sibyl T.
openaire +2 more sources
Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection
Journal of Genetic Engineering and Biotechnology, 2023 Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail +8 more
doaj +1 more source
Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2019 In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana +3 more
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