Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones [PDF]
Molecules, 2012 Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao +9 more
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Synthesis and characterization of Cu and Fe (1:2) metal complexes based on their substituted pyridones acid dyes and their application on wool fabrics [PDF]
Journal of Chemistry Letters, 2022 In this study, the investigation deals with synthesis of acid dyes from 4-amino-1-(4-sulfophenyl)- 3-methyl-5-pyrazolone and their pyridone derivatives and their metal complexes (Cu (II)and Fe (II)).
Olamide Ajani +2 more
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Solid-Phase Synthesis of Diverse Macrocycles by Regiospecific 2‑Pyridone Formation: Scope and Applications [PDF]
JACS AuSkander A. Abboud, Thomas Kodadek
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Azo-hydrazone tautomerism of aryl azo pyridone dyes [PDF]
Hemijska Industrija, 2013 In the last three or four decades disperse dyes derived from pyridones (in particular azo pyridone dyes) have gained in importance, and are widely used in various fields.
Mirković Jelena M. +3 more
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CXXXI.—Benzeneazo-2-pyridone [PDF]
J. Chem. Soc., Trans., 1908 n ...
Mills, William Hobson, Widdows, Sibyl T.
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Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection
Journal of Genetic Engineering and Biotechnology, 2023 Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail +8 more
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Heterocyclic Communications, 2022 2-Pyridone is considered as one of the most famous efficient pharmaceutical compounds. Many approaches were discovered to synthesize 2-pyridone. In this present research, chloroacetylation of benzylamine at simple conditions, EtONa/EtCOONa produced N ...
Hamed Eman O. +4 more
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Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2019 In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana +3 more
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Rhodium(I)-Complexes Catalyzed 1,4-Conjugate Addition of Arylzinc Chlorides to N-Boc-4-pyridone
Molecules, 2017 Rhodium(I)-complexes catalyzed the 1,4-conjugate addition of arylzinc chlorides to N-Boc-4-pyridone in the presence of chlorotrimethylsilane (TMSCl). A combination of [RhCl(C2H4)2]2 and BINAP was determined to be the most effective catalyst to promote ...
Fenghai Guo +5 more
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mBio, 2021 Diverse 2-pyridone alkaloids have been identified with an array of biological and pharmaceutical activities, including the development of drugs. However, the biosynthetic regulation and chemical ecology of 2-pyridones remain largely elusive.
Bo Chen +4 more
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