Results 11 to 20 of about 6,930 (204)
Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds [PDF]
2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications.
Mijin Dušan Ž.+3 more
doaj +5 more sources
The crystal structure of the title compound, C6H7NO, is stabilized by intermolecular N—H...O hydrogen bonds, resulting in inversion dimers. The structure is further consolidated by weak C—H...O hydrogen bonds.
Shulin Mao, Luo Yanghui, Pan Meiling
doaj +4 more sources
2-Pyridone: monoclinic polymorph [PDF]
The asymmetric unit in the title compound, C5H5NO, comprises two independent but virtually identical molecules of 2-pyridone, and represents a monoclinic polymorph of the previously reported orthorhombic (P212121) form [Penfold (1953). Acta Cryst. 6, 591&
Edward R. T. Tiekink+2 more
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Diversity-oriented functionalization of 2-pyridones and uracils [PDF]
Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of ...
Yong Shang+8 more
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Umpolung Synthesis of Pyridyl Ethers by BiV‐Mediated O‐Arylation of Pyridones
We demonstrate that sterically‐ and electronically‐diverse pyridyl ethers can be accessed via BiV‐mediated C−O coupling of 2‐ or 4‐pyridones with arylboronic acids. Use of a bismacyclic reagent not only confers modularity on our methodology, but also results in highly regioselective O‐arylation that is unprecedented for BiV.
Katie Ruffell+4 more
wiley +1 more source
Azo-hydrazone tautomerism of aryl azo pyridone dyes [PDF]
In the last three or four decades disperse dyes derived from pyridones (in particular azo pyridone dyes) have gained in importance, and are widely used in various fields.
Mirković Jelena M.+3 more
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CXXXI.—Benzeneazo-2-pyridone [PDF]
n ...
Mills, William Hobson, Widdows, Sibyl T.
openaire +2 more sources
Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection
Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail+8 more
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Ferrocene derivatives with planar chirality and their enantioseparation by liquid‐phase techniques
Abstract In the last decade, planar chiral ferrocenes have attracted a growing interest in several fields, particularly in asymmetric catalysis, medicinal chemistry, chiroptical spectroscopy and electrochemistry. In this frame, the access to pure or enriched enantiomers of planar chiral ferrocenes has become essential, relying on the availability of ...
Paola Peluso, Victor Mamane
wiley +1 more source
2-Pyridone is considered as one of the most famous efficient pharmaceutical compounds. Many approaches were discovered to synthesize 2-pyridone. In this present research, chloroacetylation of benzylamine at simple conditions, EtONa/EtCOONa produced N ...
Hamed Eman O.+4 more
doaj +1 more source