Results 41 to 50 of about 5,601 (174)
O- and N-Difluoromethylation of 2-Pyridones with Chlorodifluoromethane
Журнал органічної та фармацевтичної хіміїDifluoromethylation of various 2-pyridones with the available industrial reagent chlorodifluoromethane (Freon-22) has been studied. Some relationships between the ratio of difluoromethylation products and the reaction conditions, as well as the presence ...
Kirill I. Petko, Andrey A. Filatov
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Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy
Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez +3 more
wiley +1 more source
A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones
Molecules, 2019 Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied.
Federica Arioli +5 more
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Molecules, 2021 A convenient and general method for the direct synthesis of 2-aryl-6-(trifluoromethyl)-4-pyrones and 2-aryl-5-bromo-6-(trifluoromethyl)-4-pyrones has been developed on the basis of one-pot oxidative cyclization of (E)-6-aryl-1,1,1-trifluorohex-5-ene-2,4 ...
Sergey A. Usachev +5 more
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Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.An “on‐water” scalable Pd‐catalyzed heteroannulation delivers benzofurans and furopyridines at ultralow catalyst loadings (down to 0.005 mol%), providing products essentially free of palladium residues. In addition to a broad substrate scope (aryl, alkenyl, and alkyl alkynes with o‐iodophenols or 2‐iodo‐3‐hydroxypyridines), this protocol enables a new ...
Iratxe Astarloa +3 more
wiley +1 more source
Green and Eco-Friendly Multicomponent Synthesis of 2-Hydroxypyridines Under Free Solvent Conditions
Chemistry Proceedings, 2023 2-Hydroxypyridines (or commonly named 2-pyridones) are widespread nitrogen heterocycles in natural and synthetic products and their applications in biological, pharmaceutical and agrochemical compounds are becoming increasingly important.
Djamila Benzenine +5 more
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Unlocking Stereodefined Olefins by Z‐Selective Transition Metals‐catalyzed C−H Activations
ChemCatChem, Volume 18, Issue 15, 14 August 2026.The synthesis of Z‐olefins is an important challenge in synthetic organic chemistry. Within this review, we report a comprehensive overview of transition metals‐catalyzed Z‐selective C–H activations of (hetero)arenes for the synthesis of stereodefined olefins.
Francesco Capranica +2 more
wiley +1 more source
Pellagra in Contemporary Clinical Practice (2000–2023): A Systematic Review
International Journal of Dermatology, Volume 65, Issue 8, Page 1590-1599, August 2026.This systematic review (2000–2023) of 1212 cases highlights pellagra's evolving etiology. While primary dietary deficiency (85%) persists in humanitarian crises, secondary forms from alcohol misuse (9.6%), isoniazid (14.3% of drug‐related cases), and malabsorption are rising.
Noureddine Litaiem +2 more
wiley +1 more source
Kristallstruktur eines 2-Dimethylamino-3,3-dimethyl-4(3H)-pyridons
CHIMIA, 1982 3-Dimethylamino-2,2-dimethyl-2H-azirine (1) reacts with alkyl phenyl substituted cyclopropenones 2 in benzene at 130 °C to give a mixture of the two isomeric 4(3H)-pyridones 3 and 4, resulting from a nucleophilic attack at C(2) and C(1) of the ...
Jost H. Bieri +2 more
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Phenacylation of 6-Methyl-Beta-Nitropyridin-2-Ones and Further Heterocyclization of Products
Molecules, 2020 Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated.
Eugene V. Babaev, Victor B. Rybakov
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