1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis
1, 25 Dihydroxyvitamin D3 (1, 25(OH)2 D3) has gained significant importance in tuberculosis with regard to its immunoregulatory activities. Our aim was to evaluate the effect of 1, 25(OH)2 D3 on cytokine response to Mycobacterium tuberculosis antigens ...
Narayanan, P R +7 more
core +1 more source
Bone cells respond to 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) for mineral mobilization and contain receptors for 1,25(OH)2D3. We report here the expression of 25-hydroxyvitamin D3 (25 (OH)D3) metabolizing enzymes in primary cultures of human bone cells ...
Turner, R T +7 more
core +1 more source
Alveolar-Capillary Barrier Protection In Vitro: Lung Cell Type-Specific Effects and Molecular Mechanisms Induced by 1α, 25-Dihydroxyvitamin D3. [PDF]
Xiong J +10 more
europepmc +1 more source
Vitamin D and skin disorders: bridging molecular insights to clinical innovations
Growing evidence demonstrates that the immunoregulatory properties of vitamin D are primarily mediated by its active hormonal form, 1,25-dihydroxyvitamin D3 (calcitriol).
Qing Li, Hung Chan
doaj +1 more source
Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T cell mediated inflammatory demyelinating disease that is induced in mice by administration of peptides derived from myelin proteins. We developed EAE in SJL mice by administration of PLP139–151
Zaidoon Al-Jaderi, Azzam A. Maghazachi
doaj +1 more source
Rapid Actions of 1 -25-Dihydroxyvitamin D3 Physiologic Role
The steroid hormone, 1 alpha,25-dihydroxyvitamin D3 (1 alpha,25-[OH]2D3), has been shown to exert actions on cells within seconds. The rapidity of these effects has led to the speculation that they reflect nongenomic actions of the hormone which involve interaction with membrane receptors. Moreover, these rapid effects appear to modulate the actions of
D T, Baran, A M, Sorensen
openaire +2 more sources
Estudo do mecanismo de ação não-genômico da tiroxina e da 1a,25(OH)2- vitamina D3 em sistemas de membrana plasmática: transporte de aminoácidos e fluxo iônico em testículos de ratos e em células TM4 [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2009.Hormônios esteróides, vitamina D, retinóides e hormônios da tireóide estimulam respostas celulares através ...
Menegaz, Danusa
core
Synthesis of (C-11)-substituted analogues of 1α,25-dihydroxyvitamin D3
The synthesis of a series of C-ring modified analogues of 1-alpha,25-dihydroxyvitamin D3, with various alpha- and beta-oriented substituents on C-11, is described.
Van der Eycken, Johan +9 more
core +1 more source
Toll-Like Receptor Signaling in Bovine Macrophages Increases 1,25-Dihydroxyvitamin D3 Production [PDF]
Recognition of pathogen associated molecular patterns by Toll-like receptors (TLR) increases 1α-hydroxylase expression in bovine macrophages. This results in increased conversion of 25-hydroxyvitamin D3 (25(OH)D3) to 1,25- dihydroxyvitamin D3 (1,25(OH)
Nelson, Corwin +3 more
core +1 more source
The serum vitamin D status in adults with diabetic retinopathy: A systematic review and meta-analysis [PDF]
Background: Emerging evidence suggests that vitamin D may play a crucial role in the development of diabetic retinopathy (DR). However, the extent of vitamin D deficiency in individuals with DR remains uncertain.
Wei Hongyu +6 more
doaj +1 more source

