Results 1 to 10 of about 238,339 (100)

Cadmium Toxicity on Chondrocytes and the Palliative Effects of 1α, 25-Dihydroxy Vitamin D3 in White Leghorns Chicken's Embryo

Frontiers in Veterinary Science, 2021
Cadmium (Cd) can causes osteoporosis and joint swelling. However, the mechanism of Cd toxicity in chondrocytes and how to alleviate Cd poisoning to chondrocytes are still unclear.
Jianhong Gu, Jianhong Gu, Jianhong Gu, Saihui Li, Saihui Li, Guoshuai Wang, Guoshuai Wang, Xueqing Zhang, Xueqing Zhang, Yan Yuan, Yan Yuan, Xuezhong Liu, Xuezhong Liu, Xuezhong Liu, Jianchun Bian, Jianchun Bian, Jianchun Bian, Xishuai Tong, Xishuai Tong, Xishuai Tong, Xishuai Tong, Zongping Liu, Zongping Liu, Zongping Liu, Zongping Liu   +24 more
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1α,25-Dihydroxyvitamin D₃ Improves Follicular Development and Steroid Hormone Biosynthesis by Regulating Vitamin D Receptor in the Layers Model

Current Issues in Molecular Biology, 2023
1α,25-Dihydroxyvitamin D3 (VitD3) is the active form of vitamin D, and it regulates gene expression and protein synthesis in mammalian follicle development. However, the function of VitD3 in the follicular development of layers remains unclear.
Manman Cheng, Zhenquan Song, Yan Guo, Xuliang Luo, Xuelian Li, Xiaohui Wu, Yanzhang Gong   +6 more
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Gene-Regulatory Potential of 25-Hydroxyvitamin D3 and D2

Frontiers in Nutrition, 2022
Human peripheral blood mononuclear cells (PBMCs) represent a highly responsive primary tissue that is composed of innate and adaptive immune cells.
Andrea Hanel, Cor Veldhuizen, Carsten Carlberg, Carsten Carlberg   +3 more
doaj   +1 more source

IL-1ɑ C376A Transversion Variant and Risk of Idiopathic Male Infertility in Iranian Men: A Genetic Association Study [PDF]

International Journal of Fertility and Sterility, 2018
Background IL-1α produced by Sertoli cells is considered to act as a growth factor for spermatogonia. In this study, we investigated the association of the C376A polymorphism in IL-1α with male infertility in men referring to the Kashan IVF Center.
Tayyebeh Zamani-Badi, Mohammad Karimian, Abolfazl Azami Tameh, Hossein Nikzad   +3 more
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1α,25-Dihydroxyvitamin D3 Promotes Angiogenesis After Cerebral Ischemia Injury in Rats by Upregulating the TGF-β/Smad2/3 Signaling Pathway

Frontiers in Cardiovascular Medicine, 2022
Stroke is a disease with high morbidity, disability and mortality, which seriously endangers the life span and quality of life of people worldwide. Angiogenesis and neuroprotection are the key to the functional recovery of penumbra function after acute ...
Yajie Zhang, Yajie Zhang, Yingfeng Mu, Hongmei Ding, Bo Du, Mingyue Zhou, Mingyue Zhou, Qingqing Li, Qingqing Li, Shitong Gong, Shitong Gong, Fuchi Zhang, Deqin Geng, Yanqiang Wang   +13 more
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Simultaneous determination of vitamin D metabolites 25(OH)D3 and 1α,25(OH)2D3 in human plasma using liquid chromatography tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2022
Background: Although measurement of 25(OH)D3 is a routine analytical method to determine plasma vitamin D status, 1α,25(OH)2D3 is the biologically active form. Hence, simultaneous measurement of 25(OH)D3 and 1α,25(OH)2D3 could provide better insight into
Shan Xu, Rui Ni, Lihong Lv, Rui Chen, Yao Chen, Fengjiao Huang, Zhiru Xu   +6 more
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Differential Effects of 25-Hydroxyvitamin D₃ versus 1α 25-Dihydroxyvitamin D₃ on Adipose Tissue Browning in CKD-Associated Cachexia

Cells, 2021
Patients with chronic kidney disease (CKD) often have low serum concentrations of 25(OH)D3 and 1,25(OH)2D3. We investigated the differential effects of 25(OH)D3 versus 1,25(OH)2D3 repletion in mice with surgically induced CKD.
Robert H. Mak, Uwe Querfeld, Alex Gonzalez, Sujana Gunta, Wai W. Cheung   +4 more
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Urine trace element disorder along with renal function injury in vitamin D deficient diabetic rats and intervention effect of 1α,25-dihydroxyvitamin D3

Frontiers in Nutrition, 2022
IntroductionTrace element metabolism disorders are often secondary to disorders of glucose metabolism in diabetes. Although 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] could ameliorate abnormal glucose metabolism in the development of diabetes, the effect on
Dongxia Wang, Dongxia Wang, Ning Wang, Juan Zhou, Gang Luo, Yanyan Li, Wei Yu, Hongxing Tan, Gang Liu, Jun Wang, Liping Hao   +10 more
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Vitamin D3 eradicates Helicobacter pylori by inducing VDR-CAMP signaling

Frontiers in Microbiology, 2022
BackgroundVitamin D3 [VitD3, 1,25 (OH)2D3] is known to have immunomodulatory and anti-microbial properties; however, its activity against Helicobacter pylori is unclear. In this study, we established H.
Ye Zhang, Chunya Wang, Li Zhang, Jie Yu, Wenjie Yuan, Lei Li   +5 more
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Porcine Reproductive and Respiratory Syndrome Virus nsp1β Stabilizes HIF-1α to Enhance Viral Replication

Microbiology Spectrum, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) is an Arterivirus that has been devastating the swine industry worldwide since the late 1980s.
Yu Pang, Yanrong Zhou, Yuchen Wang, Zheng Sun, Jiao Liu, Chenyu Li, Shaobo Xiao, Liurong Fang   +7 more
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