Results 11 to 20 of about 62,607,340 (217)

The Relationship between Th1/Th2 Balance and 1α, 25-Dihydroxyvitamin D3 in Patients with Allergic Rhinitis [PDF]

Turkish Archives of Otorhinolaryngology, 2015
Objective:With regard to the correlation between T helper1/T helper2 (Th1/Th2) cell balance and 1α,25-dihydroxyvitamin D3, active metabolite of vitamin D, we studied Th1/Th2 cell balance by measuring levels of the cytokines interleukin (IL)-4, IL-10 and ...
Erol Keleş, Şule Özkara, Nevin İlhan, Hilal Güngör, Turgut Karlıdağ, Şinasi Yalçın   +5 more
doaj   +2 more sources

Differential Metabolic Stability of 4α,25- and 4β,25-Dihydroxyvitamin D₃ and Identification of Their Metabolites. [PDF]

Biomolecules, 2023
Vitamin D3 (1) is metabolized by various cytochrome P450 (CYP) enzymes, resulting in the formation of diverse metabolites. Among them, 4α,25-dihydroxyvitamin D3 (6a) and 4β,25-dihydroxyvitamin D3 (6b) are both produced from 25-hydroxyvitamin ...
Mizumoto Y, Sakamoto R, Iijima K, Nakaya N, Odagi M, Tera M, Hirokawa T, Sakaki T, Yasuda K, Nagasawa K.   +9 more
europepmc   +2 more sources

Metabolism of 25-hydroxyvitamin D3 to 24,25-dihydroxyvitamin D3 by blood derived macrophages from a patient with alveolar rhabdomyosarcoma during short-term culture and 1 alpha,25-dihydroxyvitamin D3 after long-term culture.

, 1991
We have examined the ability of blood-derived monocytes and macrophages isolated from a patient with alveolar rhabdomyosarcoma and hypercalcaemia, to form 24,25-dihydroxyvitamin D3 (24,25(OH)2D3) or 1 alpha,25-dihydroxyvitamin D3 (1 alpha,25(OH)2D3) from
Bayley, D, Denton, J, Hayes, M, Davies, M, Freemont, AJ; id_orcid, Drayson, M, Mawer, E.   +6 more
core   +11 more sources

1,25-dihydroxyvitamin-D3 but not the clinically applied marker 25-hydroxyvitamin-D3 predicts survival after stem cell transplantation [PDF]

, 2023
The serum level of 25-hydroxyvitamin-D3 is accepted as marker for a person’s vitamin D status but its role for the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) is controversially discussed.
Weber, Daniela, Stark, Klaus, Holler, Ernst, Peter, Katrin, Matos, Carina, Herr, Wolfgang, Ayuk, Francis, Güllstorf, Martina, Kröger, Nicolaus, Bruns, Heiko, Kreutz, Marina, Siska, Peter J., Roider, Tobias, Singer, Katrin, Wolff, Daniel, Heid, Iris M., Renner, Kathrin   +16 more
core   +3 more sources

Detection of 7-Dehydrocholesterol and Vitamin D3 Derivatives in Honey

Molecules, 2020
20(S)-Hydroxyvitamin D3 (20(OH)D3) is an endogenous metabolite produced by the action of CYP11A1 on the side chain of vitamin D3 (D3). 20(OH)D3 can be further hydroxylated by CYP11A1, CYP27A1, CYP24A1 and/or CYP27B1 to several hydroxyderivatives. CYP11A1
Tae-Kang Kim, Venkatram Atigadda, Pawel Brzeminski, Adrian Fabisiak, Edith K. Y. Tang, Robert C. Tuckey, Andrzej T. Slominski   +6 more
doaj   +1 more source

Gene expression profiles in human and mouse primary cells provide new insights into the differential actions of vitamin D3 metabolites. [PDF]

PLoS ONE, 2013
1α,25-Dihydroxyvitamin D3 (1α,25(OH)2D3) had earlier been regarded as the only active hormone. The newly identified actions of 25-hydroxyvitamin D3 (25(OH)D3) and 24R,25-dihydroxyvitamin D3 (24R,25(OH)2D3) broadened the vitamin D3 endocrine system ...
Pentti Tuohimaa, Jing-Huan Wang, Sofia Khan, Marianne Kuuslahti, Kui Qian, Tommi Manninen, Petri Auvinen, Mauno Vihinen, Yan-Ru Lou   +8 more
doaj   +1 more source

Vitamin D Metabolites and Risk of Cardiovascular Disease in Chronic Kidney Disease: The CRIC Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The ratio of 24,25‐dihydroxyvitamin D3/25‐hydroxyvitamin D3 (vitamin D metabolite ratio [VDMR]) may reflect functional vitamin D activity. We examined associations of the VDMR, 25‐hydroxyvitamin D (25[OH]D), and 1,25‐dihydroxyvitamin D (1,25 ...
Simon Hsu, Leila R. Zelnick, Nisha Bansal, Julia Brown, Michelle Denburg, Harold I. Feldman, Charles Ginsberg, Andrew N. Hoofnagle, Tamara Isakova, Mary B. Leonard, Benjamin Lidgard, Cassianne Robinson‐Cohen, Myles Wolf, Dawei Xie, Bryan R. Kestenbaum, Ian H. de Boer   +15 more
doaj   +1 more source

Affinity Labeling of the 1α,25-Dihydroxyvitamin D3 Receptor [PDF]

Journal of Biological Chemistry, 1996
Genomic actions of the calciotropic hormone 1 alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) involves a multistep process that is triggered by the highly specific binding of 1,25(OH)2D3 to 1 alpha, 25-dihydroxyvitamin D3 receptor, VDR. In order to study this key step in the cascade, we synthesized 1 alpha,25-dihydroxy[26(27)-3H]vitamin D3-3-deoxy-3 beta ...
R, Ray, N, Swamy, P N, MacDonald, S, Ray, M R, Haussler, M F, Holick   +5 more
openaire   +2 more sources

1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation [PDF]

, 2005
peer reviewed1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism.
Frahm, Thomas, Ehrchen, Jan, Lengeling, Andreas, Helming, Laura, Geffers, Robert, Probst-Kepper, Michael, Schiebe, Stefanie, L. Helming, Böse, Jens, Balling, Rudi   +9 more
core   +1 more source

TRPV6 Determines the Effect of Vitamin D3 on Prostate Cancer Cell Growth. [PDF]

, 2011
Despite remarkable advances in the therapy and prevention of prostate cancer it is still the second cause of death from cancer in industrialized countries.
Gordienko, DV, Oulidi, A, Artem Kondratskyi, Brigitte Mauroy, Lehen'kyi, V, Bonnal, Jean-Lois, Khalimonchyk, Sergii, Kondratskyi, Artem, Dmitri V. Gordienko, Mauroy, B, Skryma, R, Skryma, Roman, Dmitri V Gordienko, Bonnal, JL, Gordienko, Dmitri, Maylis Raphaël, Flourakis, M, Prevarskaya, N, Oulidi, Agathe, Natalia Prevarskaya, Kondratskyi, A, Lehen'Kyi, V'Yacheslav, Khalimonchyk, S, Flourakis, Matthieu, Prevarskaya, Natalia, Raphaël, Maylis, Sergii Khalimonchyk, Matthieu Flourakis, Agathe Oulidi, Raphaël, M, V'yacheslav Lehen'kyi, Mauroy, Brigitte, Jean-Lois Bonnal, Roman Skryma   +33 more
core   +1 more source