Results 41 to 50 of about 62,607,340 (217)

Serum 25-hydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 concentrations in adult dogs are more substantially increased by oral supplementation of 25-hydroxyvitamin D3 than by vitamin D3

Journal of Nutritional Science, 2017
We previously found a weak response in serum 25-hydroxyvitamin D3 (25(OH)D3) concentrations when dogs were supplemented with oral vitamin D3 (D3). In the present study, we determined the relative potency of oral 25(OH)D3 compared with D3 for increasing ...
Lauren R. Young, Robert C. Backus
doaj   +1 more source

Lower placental 25-hydroxyvitamin D3 (25(OH)D3) and higher placental CYP27B1 and 25(OH)D3 ratio in preterm birth

Journal of Nutritional Science, 2020
Neonatal mortality rates in Indonesia are still at an alarming rate, with preterm birth as one of the causes. Nutritional deficiencies such as low level of vitamin D is suspected to be the risk factors of preterm birth but still a little knowledge about ...
Rima Irwinda, Biancha Andardi
doaj   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

1,25-Dihydroxyvitamin D3 target cells in immature pancreatic islets

, 1987
Target cells of 1,25-dihydroxyvitamin D3 were identified by autoradiography in islets from rats of different ages. Nuclei of pancreatic islet cells selectively concentrated 1,25-[3H]dihydroxyvitamin D3 but not 25-[3H]hydroxyvitamin D3 or 24,25-[3H ...
M. Sar, H. F. DeLuca, S. A. Clark, W. E. Stumpf   +3 more
core   +1 more source

Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia

Journal of Lipid Research, 2008
1α,25-Dihydroxyvitamin D3 [1,25(OH)2D3], a vitamin D receptor (VDR) ligand, regulates calcium homeostasis and also exhibits noncalcemic actions on immunity and cell differentiation. In addition to disorders of bone and calcium metabolism, VDR ligands are
Michiyasu Ishizawa, Manabu Matsunawa, Ryutaro Adachi, Shigeyuki Uno, Kazumasa Ikeda, Hiroyuki Masuno, Masato Shimizu, Ken-ichi Iwasaki, Sachiko Yamada, Makoto Makishima   +9 more
doaj   +1 more source

Cadmium Toxicity on Chondrocytes and the Palliative Effects of 1α, 25-Dihydroxy Vitamin D3 in White Leghorns Chicken's Embryo

Frontiers in Veterinary Science, 2021
Cadmium (Cd) can causes osteoporosis and joint swelling. However, the mechanism of Cd toxicity in chondrocytes and how to alleviate Cd poisoning to chondrocytes are still unclear.
Jianhong Gu, Jianhong Gu, Jianhong Gu, Saihui Li, Saihui Li, Guoshuai Wang, Guoshuai Wang, Xueqing Zhang, Xueqing Zhang, Yan Yuan, Yan Yuan, Xuezhong Liu, Xuezhong Liu, Xuezhong Liu, Jianchun Bian, Jianchun Bian, Jianchun Bian, Xishuai Tong, Xishuai Tong, Xishuai Tong, Xishuai Tong, Zongping Liu, Zongping Liu, Zongping Liu, Zongping Liu   +24 more
doaj   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Cells isolated from embryonic intestine synthesize 1,25-dihydroxyvitamin-D3 and 24,25-dihydroxyvitamin-D3 in culture

, 1983
Cells isolated from embryonic chick intestine in culture convert 25-hydroxyvitamin-D3 to a number of more polar metabolites. Two of these metabolites have been identified with chemical and chromatographic methods as 24,25-dihydroxyvitamin-D3 (24,25(OH ...
Turner, R T, Baylink, D J, Puzas, J E, Howard, G A, DAVID J. BAYLINK, RUSSELL T. TURNER, J. EDWARD PUZAS, GUY A. HOWARD   +7 more
core   +1 more source

Novel Heteroatom-containing Vitamin D3 Analogs: Efficient Synthesis of 1α,25-Dihydroxyvitamin D3-26,23-lactam

Molecules, 2003
Vitamin D3 and its synthetic analogs are promising compounds for controlling various types of cell differentiation. In this article, we describe the synthesis of novel vitamin D3 analogs containing heteroatoms in their side chains – so-called ...
Kazuo Nagasawa, Yuichi Hashimoto, Yuko Kato   +2 more
doaj   +1 more source

Association Between Genetically Predicted 25‐Hydroxyvitamin D and Type 2 Diabetes Risk in South Asians: An Exploratory Two‐Sample Mendelian Randomization Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Using two‐sample Mendelian randomization, we found no statistically significant association between genetically predicted 25‐hydroxyvitamin D and Type 2 diabetes risk in South Asians. However, the limited exposure GWAS, three‐instrument set, exploratory instrument threshold, and possible sample overlap warrant cautious interpretation and larger South ...
Adina Zaka, Suleman Khan, Asim Shah, Aizaz Anwar Khalid, Ibrahim Khalil, A. B. M. Kamrul‐Hasan   +5 more
wiley   +1 more source