Results 61 to 70 of about 62,607,340 (217)
, 2011 1 alpha,25-Dihydroxyvitamin D3 exerts rapid nongenomic effects on rat osteoblast-like cells independent of the classic nuclear receptor. These effects include changes in phospholipid metabolism and cell calcium.
Lian, Jane B. +3 more
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Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACT Gynaecological malignancies account for over 1.4 million new diagnoses, with outcomes constrained by late‐stage presentation and chemoresistance. Dysregulated redox homeostasis is a hallmark of tumourigenesis. Tumour cells maintain elevated basal reactive oxygen species (ROS), which support proliferative signalling but may also increase ...
Hoi Ching Cherry Chan +4 more
wiley +1 more source
Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration
Nature Communications, 2020 Vitamin D is a precursor of the steroid hormone 1,25-dihydroxyvitamin D3, and its deficiency is associated with many adverse health outcomes. Here, Revez et al.
Joana A. Revez +20 more
doaj +1 more source
Tolerogenic Programming Promotes Human Cytomegalovirus Permissiveness in Dendritic Cells
European Journal of Immunology, Volume 56, Issue 10, October 2026.Tolerogenic programming renders dendritic cells more permissive to HCMV infection and limits their capacity to stimulate T cells. These findings suggest that tolerogenic DCs serve as a permissive cellular niche that may facilitate HCMV immune evasion. ABSTRACT Dendritic cells (DCs) are important targets of human cytomegalovirus (HCMV), yet the factors ...
Katharina Rahmel‐Stein +5 more
wiley +1 more source
Journal of Bone and Mineral Research, 1990 Abstract 1α,25-Dihydroxyvitamin D3 rapidly increases cytosolic calcium and alters membrane phospholipid metabolism in hepatocytes. To define the causal relationship between these events, we examined the effects of 1α,25-dihydroxyvitamin D3 on 32P-labeled lysophosphatidylinositol levels and cytosolic calcium as affected by pertussis toxin
D T, Baran +4 more
openaire +2 more sources
Prevalence of vitamin D deficiency its related factors in AqQala city in 2016
مجله دانشگاه علوم پزشکی بیرجند, 2017 Background and Aim: Vitamin D is provided through dietary intake or synthesis in the skin by ultraviolet ray from sunlight. Vitamin D has a significant role in calcium homeostasis and cellular growth and facilitating normal immune system function.
Abdolghader Taene +4 more
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Food Science &Nutrition, Volume 14, Issue 10, October 2026.Vitamin D is an essential fat‐soluble nutrient primarily obtained through cutaneous synthesis triggered by ultraviolet exposure and dietary intake. After systemic metabolism and activation, it binds to vitamin D receptors widely distributed in the central and peripheral nervous systems, exerting pleiotropic neuroprotective and regulatory biological ...
Nan Zhao +4 more
wiley +1 more source
Biological and Pharmaceutical Bulletin, 2000 Using six different cultured cell models representing osteoblast, intestine, kidney and keratinocyte, we have demonstrated that 1alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)2D3) is metabolized into 3-epi-1alpha,25(OH)2D3 in vitamin D-target cells. Although differences existed in the amount of 3-epi-1alpha,25(OH)2D3 formed with different cell types, it ...
MASUDA, Sonoko +7 more
openaire +3 more sources
Physiology of 24,25-dihydroxyvitamin D3 in normal human subjects
, 1982 We determined the metabolic clearance and production rates of 24,25-dihydroxyvitamin D3 in four normal healthy adults. We also examined the excretion of radioactivity in stool, urine, and bile after the intravenous administration of 24,25-[3H ...
R. Wiesner, R. Kumar, M. Scott, V. L. Go
core +1 more source
Lifestyle impact on serum level of vitamin D and PTH, in elderly
Millenium, 2017 Introduction: The aging process is responsible for health decline and may lead to the dependence and consequent institutionalization. Bone metabolism involves serum calcium regulators, such as vitamin D and PTH.
Marta Ribeiro +2 more
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