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A Comparison between Serum 25-Hydroxyvitamin D3 Levels and Serum Ferritin in Children and Adolescents with Iron Deficiency Anemia, Thalassemia Minor, Thalassemia Major and Healthy People.

Iran J Public Health
Hemmatipour A, Kikhaei B, Jalkani R, Ahmadnejad M, Soleimanzadeh F, Rokhafrooz D.   +5 more
europepmc   +1 more source

Absorption, distribution, and transport of vitamin D3 and 25-hydroxyvitamin D3 in the rat

American Journal of Physiology-Endocrinology and Metabolism, 1983
The absorption of [14C]vitamin D3 and 25-[3H]hydroxyvitamin D3 into the mesenteric lymph and portal vein after simultaneous instillation in rat duodenum has been studied. The appearance of both isotopes in the mesenteric lymph and portal vein during the first 2 h was negligible. After 2-4 h the isotopes appeared both in the lymph and portal vein.
S, Dueland, J I, Pedersen, P, Helgerud, C A, Drevon   +3 more
openaire   +3 more sources

Evidence for extrarenal metabolism of 25-hydroxyvitamin D3 in man

Clinical Science, 1986
1. Metabolites of vitamin D3 were measured in the circulation of four patients on chronic haemodialysis (three of whom were surgically anephric) before and during daily ingestion of 40000 i.u. of cholecalciferol. 2. Circulating 24,25-dihydroxyvitamin D3 [24,25-(OH)2D3] was measurable, but abnormally low before treatment; its ...
L. J. Fraher, ADAMI, Silvano, S. E. Papapoulos, H. L. Sudan, R. J. Mcgonigle, V. Parsons, O. R. Jl   +6 more
core   +5 more sources

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Overestimation of 25-Hydroxyvitamin D3 by Increased Ionisation Efficiency of 3-Epi-25-Hydroxyvitamin D3 in LC–MS/MS Methods Not Separating Both Metabolites as Determined by an LC–MS/MS Method for Separate Quantification of 25-Hydroxyvitamin D3, 3-Epi-25-Hydroxyvitamin D3 and 25-Hydroxyvitamin D2 in Human Serum

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2014
An LC-MS/MS method was developed for simultaneous quantification of 25-hydroxyvitamin D3 (25(OH)D3), 3-epi-25(OH)D3, and 25(OH)D2 in human serum.Sample preparation consisted of protein precipitation followed by off-line SPE. Calibration curves for each vitamin D metabolite were constructed in phosphate-buffered saline with 60 g/L albumin including its ...
Henny van Daal, Johannes M W van den Ouweland, Antonius M Beijers   +2 more
exaly   +3 more sources

Measurement of Plasma 25-Hydroxyvitamin D2, 25-Hydroxyvitamin D3 and 3-Epi-25-Hydroxyvitamin D3 in Population of Patients With Cardiovascular Disease by UPLC-MS/MS Method

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2020
Vitamin D has a potential role in protecting against cardiovascular disease (CVD). Serum 25-hydroxyvitamin D (25D) is the most widely used indicator of vitamin D status in the human body. 25D is estimated as total of 25-hydroxyvitamin D2 (25D2) and 25-hydroxyvitamin D3 (25D3).
Łukasz Kruszyna, Franciszek K Główka, Kornel Pawlak   +2 more
exaly   +3 more sources

Validation of the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 ratio as a biomarker of 25-hydroxyvitamin D3 clearance

The Journal of Steroid Biochemistry and Molecular Biology, 2022
The formation of 24,25-dihydroxyvitamin D (24,25(OH)2D) from 25-hydroxyvitamin D (25(OH)D) is the primary mechanism for the metabolic clearance of 25(OH)D, and is regulated by tissue-level vitamin D activity. The ratio of 24,25(OH)2D3 to 25(OH)D3 in blood (vitamin D metabolite ratio, VDMR) is postulated to be a marker of 25(OH)D3 clearance, however ...
Simon Hsu, Leila R. Zelnick, Yvonne S. Lin, Cora M. Best, Bryan R. Kestenbaum, Kenneth E. Thummel, Andrew N. Hoofnagle, Ian H. de Boer   +7 more
openaire   +2 more sources