Results 91 to 100 of about 17,890 (211)

Remarkable electronic effect on the total stereoselectivity of the cycloaddition reaction of arylnitrile oxides with pyrrol-2-one derivatives

open access: yesHeterocyclic Communications, 2019
The regiospecific 1,3-dipolar cycloaddition of 1,5-dihydropyrrol-2-one and arylnitrile oxides derivatives have been investigated. The asymmetric induction expected by the chiral centre of the 5-hydroxy-3-methyl-1,5-dihydropyrrol-2-one derivatives was ...
Guesmi A, Hamadi N Ben
doaj   +1 more source

Asymmetric Lewis acid-catalyzed 1,3-dipolar cycloadditions [PDF]

open access: yes, 2017
Highly tuned, one-point binding chiral iron and ruthenium complexes selectively coordinate and activate α,β-unsaturated aldehydes and ketones toward asymmetric catalytic Diels-Alder cycloaddition reactions.
Brinkmann, Yasmin   +3 more
core  

Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso   +2 more
wiley   +1 more source

Synthesis of spiro[isoindole-1,5’-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction

open access: yesBeilstein Journal of Organic Chemistry, 2016
A series of spiro[isoindole-1,5-isoxazolidin]-3(2H)-ones has been synthesized by 1,3-dipolar cycloaddition of N-benzylnitrone with isoindolin-3-methylene-1-ones.
Salvatore V. Giofrè   +10 more
doaj   +1 more source

Ultrasound-Assisted Synthesis of 1-N-glycosyl-1H-1,2,3-Triazole Derivatives and their Anti-inflammatory Activity

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
We have been synthesized various glycosyl triazoles from the reaction between glycosyl azide (1) and terminal alkynes (2a-g). The glycopiranosyl 1,2,3-triazoles (3-9) have been obtained in moderate-to-excellent yields (63-99%) through the copper (I ...
Gilson Bezerra Silva   +1 more
doaj   +1 more source

Synthesis of Chromen[4,3-b]pyrrolidines by Intramolecular 1,3-Dipolar Cycloadditions of Azomethine Ylides: An Experimental and Computational Assessment of the Origin of Stereocontrol [PDF]

open access: yes, 2015
Azomethine ylides, generated from imine-derived O-cinnamyl or O-crotonyl salicylaldeyde and α-amino acids, undergo intramolecular 1,3-dipolar cycloaddition, leading to chromene[4,3-b]pyrrolidines.
Arrieta, Ana   +8 more
core   +2 more sources

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

open access: yesChemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger   +3 more
wiley   +1 more source

Acid-Labile Traceless Click Linker for Protein Transduction [PDF]

open access: yes, 2012
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M.   +21 more
core   +1 more source

Recent Progress on Giant Molecules: Synthesis, Assembly, and Applications

open access: yesChemistry–Methods, Volume 6, Issue 3, March 2026.
Giant molecules are molecules constructed by molecular nanoparticles with precise, rigid structure, have similar structures with small molecules and a large size as macromolecules. In this review, the constituent modules of giant molecules, as well as their synthesis, self‐assembly, applications in various fields and future developing prospect are ...
Haoyu Chen   +7 more
wiley   +1 more source

1,3-Dipolar cycloadditions of azomethine imines [PDF]

open access: yes, 2015
Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen   +2 more
core   +3 more sources

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