Decarboxylation-Driven Double Annulations: Innovative Multi-Component Reaction Pathways [PDF]
MoleculesA concerted five-component reaction strategy has been developed, featuring double [3+2] cycloadditions utilizing aspartic acid. This approach provides valuable insights into mechanistic pathways, allowing for the distinction between concerted and ...
Desheng Zhan +4 more
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Synthesis of Trifluoromethylated Spiroisoxazolones via a [3+2] Cycloaddition of Nitrile Imines and Unsaturated Isoxazolones [PDF]
MoleculesA strategy for constructing trifluoromethylated spiroisoxazolones has been developed. This approach relies on the 1,3-dipolar cycloaddition of CF3-substituted nitrile imines, generated in situ from trifluoroacetyl hydrazonoyl bromides and K2CO3, with the
Wei Zhang, Da-Ming Du
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Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. [PDF]
, 2015 Density functional theory (DFT) calculations and experiments in tandem led to discoveries of new reactivities and selectivities involving bioorthogonal sydnone cycloadditions.
Houk, KN +3 more
core +1 more source
Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]
, 2015 The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy +3 more
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1, 3-Dipolar Cycloadditions. LXXVI. Cycloadditions of Diazomethane to Substituted Butadienes
Chemical and Pharmaceutical Bulletin, 1975 1-Substituted butadienes (R=CH2, CH3, O, C3H5, CO2CH3, CN) and 2-phenylbutadiene accept diazomethane at the 3, 4-bond yielding 3-vinylpyrazoline derivatives. Tautomerization of the 1-to 2-pyrazolines takes place either at room temperature (R=CO2CH3, CN), on heating (R=C6H5) or on acid catalysis (R=H, CH3, OCH3) ; the 2-pyrazolines are characterized as ...
ROLF HUISGEN +2 more
openaire +2 more sources
Synthesis of New N-phenyl Fulleroisoxazoline in the Presence of Fe3O4@SiO2 Nanoparticles as an Efficient Magnetically Recoverable and Reusable Catalyst [PDF]
Journal of Nanostructures, 2014 In this research an effective and appropriate method has been developed for one-pot synthesis of new N-phenyl fulleroisoxazoline using Fe3O4@SiO2 nanoparticles as a green magnetically recyclable catalyst. The prepared catalytic samples were characterized
J. Safaei-Ghomi, R. Masoomi
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SynOpen, 2022 An efficient organo-photocatalytic method for the synthesis of tetrasubstituted pyrroles bearing a ketone, ester, alcohol, or nitro group at the 3-position has been developed.
Lalita Devi +3 more
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Ferrocene-derived P,N ligands : synthesis and application in enantioselective catalysis [PDF]
, 2013 Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis.
Noël, Timothy, Van der Eycken, Johan
core +1 more source
Beilstein Journal of Organic Chemistry, 2008 Copper-catalyzed, thermal or microwave promoted 1,3-dipolar cycloaddition (Click Reaction) of 2-propynyl and 3-butynyl 2,3,4-tri-O-acetyl-6-azido-6-deoxy-glycopyranosides in the D-gluco, D-galacto and D-manno series afford the corresponding dimeric ...
Nikolas Pietrzik +2 more
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Side-chain Modifications of Highly Functionalized 3(2H)-Furanones
Molecules, 2012 A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives.
Gil Valdo José da Silva +3 more
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