Novel Enzymatic Synthesis of 3-hydroxybutyric Acid Oligomerswith Inserted Lactobionic Acid Moieties
, 2011 3-Hydroxybutyric acid and lactobionic acid yielded linear and cyclic oligomers in a lipase-catalyzedcondensation polymerization reaction, performed at 80°C in bulk and organic solvent systems. Novozyme435 was the most efficient biocatalyst, and a mixture of t-butanol and dimethylsulfoxide in 80:20 (v/v) ratioprovided the highest copolymer conversions ...
Sándor Kakasi-Zsurka +7 more
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𝜷-hydroxybutyric acid attenuates oxidative stress and improves markers of mitochondrial function in the HT-22 hippocampal cell line [PDF]
Journal of Integrative Neuroscience, 2021 Ketone bodies have been the topic of research for their possible therapeutic neurotropic effects in various neurological diseases such as Parkinson’s disease, dementia, and seizures.
Mohammed Majrashi +11 more
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Recovery and characterization of poly(3-hydroxybutyric acid) synthesized in Alcaligenes eutrophus and recombinant Escherichia coli [PDF]
Applied and Environmental Microbiology, 1995 Sei Kwang Hahn +2 more
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Serum Metabolomic Study on the Difference between Mild and Severe Acute Pancreatitis Based on Liquid Chromatography-tandem Mass Spectrometry [PDF]
Zhongguo quanke yixue, 2023 Background Mild acute pancreatitis (MAP) has a certain probability of transforming into severe acute pancreatitis (SAP) . Once SAP occurs, it will cause greater harm to patients. It is meaningful for diagnosis and treatment of pancreatitis to explore the
HUANG Xiangping, WU Ling, TAN Chaochao
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Acid-tolerant poly(3-hydroxybutyrate) hydrolases from moulds [PDF]
FEMS Microbiology Letters, 1988 We have isolated some mould strains that can grow under acid conditions with poly(3-hydroxybutyrate) (PHB) as sole carbon source, and secrete PHB hydrolases active at pH values at least down to 3. An improved assay method for such enzymes using a pH stat has been developed, and used to determine the dependence of reaction rate on enzyme and polymer ...
Douglas W. McLellan, Peter J. Halling
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Multi-Omics Analyses Reveal the Mechanisms of Early Stage Kidney Toxicity by Diquat
Toxics, 2023 Diquat (DQ), a widely used bipyridyl herbicide, is associated with significantly higher rates of kidney injuries compared to other pesticides. However, the underlying molecular mechanisms are largely unknown.
Huazhong Zhang +7 more
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Targeted and untargeted metabolomic approach for GDM diagnosis
Frontiers in Molecular Biosciences, 2023 Gestational diabetes mellitus (GDM) is a disorder which manifests itself for the first time during pregnancy and is mainly connected with glucose metabolism.
Izabela Burzynska-Pedziwiatr +14 more
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Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics
Metabolites, 2021 Although heroin and morphine are structural analogues and morphine is a metabolite of heroin, it is not known how the effect of each substance on metabolites in vivo differs. Heroin and morphine were administered to C57BL/6J mice in increasing doses from
Wuhuan Lu +9 more
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Frontiers in Psychiatry, 2020 BackgroundAutism spectrum disorder (ASD) is a type of neurodevelopmental disease that is frequently accompanied by sleep disorder. Herein, we investigated changes in the gut microbiota and its metabolites correlated with core symptoms and sleep problems ...
Xueying Hua +13 more
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