Results 11 to 20 of about 2,065 (80)

Synthesis, Radiochemical Characterization, and Biodistribution of a ¹⁸⁸Re Analogue of [¹³¹I]mIBG in a Neuroblastoma Xenograft Model. [PDF]

J Labelled Comp Radiopharm
A 188Re analogue of [131I]mIBG was synthesized in moderate yields using 188Re‐4 + 1 chemistry. In vitro studies using SK‐N‐SH neuroblastoma cell lines demonstrated that the compound exhibited affinity for norepinephrine transporters expressed on these cancer cells.
Sakhare N, Kumar D, Das S, Mitra A, Mirapurkar S, Rani G, Sheela M, Chirayil V, Mohanty B, Mathur A, Mallia MB, Chaudhari P.   +11 more
europepmc   +2 more sources

A case of marked improvement in pareidolia in untreated schizophrenia following antipsychotic treatment. [PDF]

PCN Rep
Abstract Background Pareidolia, the tendency to perceive meaningful images within ambiguous visual patterns, is commonly observed in neurodegenerative disorders and schizophrenia. Owing to the limited number of studies, the characteristics of pareidolia accompanying schizophrenia remain unclear.
Kato T, Seki E, Kumasaka T, Tsujii T, Mochizuki D, Kida H, Nikkuni S, Mizuno M, Sakuma K.   +8 more
europepmc   +2 more sources

Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195

EJNMMI Research, 2018
Background 18F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine (18F-LMI1195) is a new class of PET tracer designed for sympathetic nervous imaging of the heart.
Xinyu Chen, Rudolf A. Werner, Constantin Lapa, Naoko Nose, Mitsuru Hirano, Mehrbod S. Javadi, Simon Robinson, Takahiro Higuchi   +7 more
doaj   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Carmen Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Evaluation of pharmacokinetics, safety, and efficacy of [211At] meta-astatobenzylguanidine ([211At] MABG) in patients with pheochromocytoma or paraganglioma (PPGL): A study protocol.

PLoS ONE
BackgroundPheochromocytoma, or paraganglioma (PPGL), is a tumor that arises from catecholamine-producing chromaffin cells of the adrenal medulla or paraganglion.
Masao Kobayakawa, Tohru Shiga, Kazuhiro Takahashi, Shigeyasu Sugawara, Kaori Nomura, Kazuhiko Hanada, Naoki Ishizuka, Hiroshi Ito   +7 more
doaj   +1 more source

Interleucina 1β correlaciona-se com MIBG e parâmetros do exercício, na insuficiência cardíaca? Do interleukin-1β levels correlate with MIBG and exercise parameters in heart failure?

Arquivos Brasileiros de Cardiologia, 2013
FUNDAMENTO: Na insuficiência cardíaca, níveis de interleucina 1β (IL 1β) se associam a prognóstico. A atividade adrenérgica cardíaca avaliada através da cintilografia com metiodobenzilguanidina (I123 MIBG) e parâmetros do exercício são ...
Leandro Rocha Messias, Maria Angela M. de Queiroz Carreira, Sandra Marina Miranda, Jader Cunha de Azevedo, Paula Cardoso Benayon, Ronaldo Campos Rodrigues, Elisabeth Maróstica, Evandro Tinoco Mesquita, Claudio Tinoco Mesquita   +8 more
doaj  

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, Volume 309, Issue 2, Page 417-450, February 2026.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Tasha K. Phillips, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +16 more
wiley   +1 more source