Results 21 to 30 of about 2,065 (80)
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller +5 more
wiley +1 more source
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay +12 more
wiley +1 more source
Histologic Response to Induction Chemotherapy in High‐Risk Neuroblastoma
ABSTRACT Introduction Tumor histology at diagnosis is used in conjunction with other prognostic features to risk stratify patients with neuroblastoma and to assign therapy regimens. In patients with high‐risk disease, adjustment of therapy is tailored to treatment response, largely based on disease imaging following induction chemotherapy and resection
Monica Pomaville +4 more
wiley +1 more source
ABSTRACT Objectives The primary objective was to assess the accuracy of prenatal examination in detecting and characterizing perinatal solid tumors of the thoracoabdominopelvic region. Secondary objectives were to describe the epidemiology, clinical characteristics and outcome of these tumors.
C. Khawand +23 more
wiley +1 more source
Abstract Dementia with Lewy bodies (DLB), a progressive neurodegenerative disease with heterogeneous clinical presentations, greatly impacts patients, caregivers, and society. Despite its frequency, diagnosing and treating DLB remains challenging. Advances in in vivo biomarker assays reflecting underlying pathology are improving disease identification,
Jennifer G. Goldman +19 more
wiley +1 more source
Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley +1 more source
Progranulin Mutation Manifesting as Parkinson Disease: A Case Series from the PADUA‐CESNE Cohort
Abstract Background Mutations in progranulin (GRN) are associated with frontotemporal dementia, although a Parkinson disease (PD) phenotype is uncommon, especially in young patients. Cases We report three subjects from the PADUA‐CESNE cohort, meeting diagnostic criteria for PD, with onset under age 55.
Giulia Bonato +8 more
wiley +1 more source
Beyond fluorodeoxyglucose: Molecular imaging of cancer in precision medicine
Abstract Cancer molecular imaging is the noninvasive visualization of a process unique to or altered in neoplasia, such as proliferation, glucose metabolism, and receptor expression, which is relevant to patient management. Several molecular imaging modalities are now available, including magnetic resonance, optical, and nuclear imaging.
Malik E. Juweid +6 more
wiley +1 more source
Pheochromocytoma‐Induced Reversible Dilated Cardiomyopathy: A Case Report and Literature Review
ABSTRACT Pheochromocytoma is a rare, primarily benign tumor that arises from the chromaffin cells of the adrenal medulla. It is known for causing excessive secretion of catecholamines, such as epinephrine and norepinephrine. This condition poses significant health risks due to its potential to cause severe cardiovascular complications, including ...
Fatemeh Afra +4 more
wiley +1 more source
Abstract INTRODUCTION The Alzheimer's Association and the Society of Nuclear Medicine and Molecular Imaging convened a multidisciplinary workgroup to update appropriate use criteria (AUC) for amyloid positron emission tomography (PET) and to develop AUC for tau PET.
Gil D. Rabinovici +15 more
wiley +1 more source

