Impairment of hydrogen sulfide synthesis in chondrocytes under high glucose environment: a link between type 2 diabetes and osteoarthritis [PDF]
, 2018 Poster ...
Blanco García, Francisco J +3 more
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Journal of Advanced Research, 2021 Background: Over the last several decades, hydrogen sulfide (H2S) has been found to exert multiple physiological functions in mammal systems. The endogenous production of H2S is primarily mediated by cystathione β-synthase (CBS), cystathione γ-lyase (CSE)
Hai-Jian Sun +4 more
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The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues [PDF]
, 2011 The enzymes of the transsulfuration pathway, cystathionine --synthase (CBS) and cystathionine --lyase (CSE), are important for the endogenous production of hydrogen sulfide (H2S), a gaseous signaling molecule. The relative contributions of CBS and CSE to
Kery V +6 more
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Escherichia coli Uses Separate Enzymes to Produce H2S and Reactive Sulfane Sulfur From L-cysteine
Frontiers in Microbiology, 2019 Hydrogen sulfide (H2S) has been proposed to have various physiological functions, and it may function through reactive sulfane sulfur. Since the two sulfur forms often coexist, they are normally considered interchangeable.
Kai Li +7 more
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A Proteomic Approach to Study the Effect of Thiotaurine on Human Neutrophil Activation [PDF]
, 2017 Thiotaurine, a thiosulfonate related to taurine and hypotaurine, is formed by a metabolic process from cystine and generated by a transulfuration reaction between hypotaurine and thiocysteine.
A Ferrante +33 more
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Hypertension and Aging Affect Liver Sulfur Metabolism in Rats
Cells, 2021 Hypertension and age are key risk factors for cardiovascular morbidity and mortality. Hydrogen sulfide (H2S), a gaseous transmitter, contributes significantly to regulating arterial blood pressure and aging processes.
Dominika Szlęzak +4 more
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The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide (AP39) [PDF]
, 2014 Synthesis and bioavailability of the endogenous gasomediator hydrogen sulfide (H2S) is perturbed in many disease states, including those involving mitochondrial dysfunction.
Cai +54 more
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Redox Biology, 2022 Background & aims: Excessive inflammatory responses and oxidative stress are considered the main characteristics of inflammatory bowel disease (IBD). Endogenous hydrogen sulfide (H2S) has been reported to show anti-inflammatory activity in IBD.
Jie Zhang +15 more
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Past, present and future of cyanide antagonism research: From the early remedies to the current therapies. [PDF]
, 2015 This paper reviews milestones in antidotal therapies for cyanide (CN) spanning early remedies, current antidotal systems and research towards next generation therapies. CN has been a part of plant defense mechanisms for millions of years.
Budai, Marianna +3 more
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The double-edged sword role of hydrogen sulfide in hepatocellular carcinoma
Frontiers in Pharmacology, 2023 With an increasing worldwide prevalence, hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver in the world. It is also the primary reason for cancer-related death in the world. The pathogenesis of HCC is complex, such as
Huijie Zhao +7 more
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