Results 111 to 120 of about 13,314,497 (296)

New 1,2,3-Triazole-genipin Analogues and Their Anti-Alzheimer’s Activity

open access: yes
A novel series of 1,2,3-triazole-genipin analogues were designed, synthesized, and evaluated for neuroprotective activity, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) inhibitory activity.
Jiraporn Tocharus (4672513)   +5 more
core   +1 more source

Triazole-Modified Calix[4]crown as a Novel Fluorescent On−Off Switchable Chemosensor

open access: yes, 2007
A novel fluorescent on−off switchable chemosensor 1 with two different types of cationic binding sites is synthesized, which is composed of a triazole-modified calix[4]crown in the 1,3-alternate conformation.
In-Hao Su (8660367)   +3 more
core   +1 more source

Unlocking Catalyst Activation as a Critical Bottleneck in Cross‐Coupling Reactions: Room‐Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1‐MeNAP)TFA]2 Precatalysts

open access: yesAngewandte Chemie International Edition, EarlyView.
In many Pd‐catalyzed cross‐couplings, catalyst performance has been found to be limited by catalyst activation. Methylnaphthyl (MeNAP) palladium trifluoroacetate dimers are presented as easy‐to‐store and easy‐to‐handle precursors, which rapidly activate under reaction conditions, even when only weakly coordinating, non‐reducing nucleophiles are present.
Sourav Manna   +6 more
wiley   +1 more source

The study of analgesic effect of 5-(furan-2-yl, 2-methylfuran-3-yl)-4-amino-1,2,4-triazole-3-thion derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Introduction. The nucleus of 1,2,4-triazole is the subject of close attention from a wide range of scientists because of numerous unique properties. Analyzing literary sources, it should be noted that there is a large amount of information devoted to the
D. M. Danilchenko
doaj   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

open access: yesAngewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner   +2 more
wiley   +1 more source

SÍNTESE E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE DERIVADOS DO EUGENOL CONTENDO NÚCLEOS 1,2,3-TRIAZÓLICOS

open access: yesQuímica Nova
Eugenol is an aromatic compound found in several plant species. It presents important biological activities including cytotoxicity. In this paper, it is described the synthesis and the evaluation of the cytotoxic activity of eugenol derivatives bearing 1,
Poliana Aparecida Rodrigues Gazolla   +8 more
doaj   +1 more source

1, 2, 3-Triazole appended L-asorbic acid with antioxidant properties

open access: yes24. hrvatski skup kemičara i kemijskih inženjera: knjiga sažetaka, 2015
1, 2, 3-Triazoles have attracted considerable attention in recent years because of their wide range of biological activities against various viruses, malignant cells, microorganisms and their inhibitory activities against several enzymes [1]. Furthermore, since the discovery of vitamin C, the number of its known biological functions is continually ...
Stepanić, Višnja   +3 more
openaire  

Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: a lethal combination

open access: yes, 2022
We report a case of severe COVID-19 pneumonia complicated by fatal co-infection with a multi-triazole resistant Aspergillus fumigatus and highlight the importance of recognising the significance of Aspergillus sp.
Marta Trzos-Grzybowska (12238392)   +8 more
core   +1 more source

A Fixed‐Charge Interphase Synchronizes Ion Transport to Suppress Space‐Charge‐Driven Inefficiency Under Nanoliter Confinement

open access: yesAngewandte Chemie International Edition, EarlyView.
Electrochemical energy storage breaks down under extreme miniaturization, where interfaces and space‐charge dominate device behavior. This work introduces a fixed‐charge selective interphase (FCSI) integrated into a twin‐tube micro‐Swiss‐roll architecture.
Yaping Yan   +12 more
wiley   +1 more source

Theoretical Study of Tautomeric Conformations for 1,2,4-Triazole Derivatives

open access: yesOrbital: The Electronic Journal of Chemistry, 2021
We have performing theoretical calculations of the 1,2,4-triazole derivatives using DFT B3LYP method to study the tautomeric conformations of 1,2,4-triazole-3-thiol (TL 2A and TL 2C) and 1,2,4-triazole-3-thione (TL 2B) derivatives.
Radia Mahboub
doaj  

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