Results 121 to 130 of about 13,314,497 (296)
Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies. [PDF]
Pharmaceuticals (Basel), 2020 Alam MM +5 more
europepmc +1 more source
Dataset on the DFT-QSAR, and docking approaches for anticancer activities of 1, 2, 3-triazole-pyrimidine derivatives against human esophageal carcinoma (EC-109). [PDF]
Data Brief, 2020 Adegoke RO, Oyebamiji AK, Semire B.
europepmc +1 more source
1, 2, 3-Triazole appended L-ascorbic acid with antioxidant properties
, 2016 Since the discovery of vitamin C, the number of its known biological functions is continually expanding. Various pyrimidines and purines containing L-ascorbic acid exhibited significant antiproliferative effects against malignant human tumour cell lines.1 Vitamin C is a biologically significant reducing agent due to its 1-oxo-2- ene-2, 3-diol ...
Kraljević Pavelić, Sandra +4 more
openaire +1 more source
N-Unsubstituted 1,2,4-Triazole-3-carbaldehydes
, 1971 A series of N-unsubstituted 1,2,4-triazole-3-carbaldehydes has been prepared by acid hydrolysis of their methyl or ethyl acetals. Those with 5-aryl substituents have been shown to dimerize in the solid state to carbonyl-free hemiaminals. P.m.r.
EJ Browne
core +1 more source
Synthesis of 3-triazole-nor-β-lapachones with potential trypanocidal activity [PDF]
Proceedings of the 15th Brazilian Meeting on Organic Synthesis Proceedings, 2013 Mariana F. do Carmo Cardoso +5 more
openaire +1 more source
Animal Research and One Health, EarlyView.This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen +2 more
wiley +1 more source
Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor
Bulletin of the Korean Chemical Society, EarlyView.This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim +8 more
wiley +1 more source
, 2016 Mono-, bis-, and tris-1,2,3-triazole ligands are used for the stabilization of gold nanoparticles (AuNPs), and the catalytic activities of these AuNPs in 4-nitrophenol reduction by NaBH4 in water are compared as well as with polyethylene glycol 2000 (PEG)
Sergio Moya (1353486) +7 more
core +1 more source
Carbon Energy, EarlyView.New hierarchical ZIF‐derived nitrogen‐doped carbons (ZDCs) impregnated with LiCl are promising materials for sorption thermal batteries utilizing solar energy. This study examines the structural properties of ZDCs, the effect of LiCl loading, the enhancement of hydrothermal stability by nanoporous carbon, and the water adsorption properties of a series
Jan Marčec +7 more
wiley +1 more source
, 2019 Two CuII coordination complexes {[Cu(L430)(H2O)2](NO3)2}n (I) and {[Cu(L430)2(H2O)2](ClO4)2(H2O)0.3}n (II) have been synthesized based on 3-phenyl-4-(3-pyridyl)-5-(4-pyridyl)-1,2,4-triazole (L430) in the presence of different anions (CIF file CCDC nos ...
Si Wang (519067) +2 more
core +1 more source