Results 11 to 20 of about 47,847 (251)

Quinolinyl Triazole Derivatives-Dominant Inhibitors for Mild Steel in Hydrochloric Acid [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2022
Quinolinyl triazole derivatives 4-(4-chlorophenyl)-5-{[(5-chloroquinolin-8-yl)oxy]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione (4-4CPCQMT), 4-(3-chlorophenyl)-5-{[(5-chloroquinolin-8-yl)oxy]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione (4-3CPCQMT) and
Nitin Kumar Shetty   +1 more
doaj   +1 more source

1,2,3-Triazole-Based Hybrids as EGFR Inhibitors: An overview [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences
Cancer continues to be a leading cause of mortality worldwide, presenting a major global public health concern. Despite advances in treatment, the discovery and development of effective anticancer drugs remain significant challenges for medicinal ...
Asmaa Yassen   +4 more
doaj   +1 more source

The search for new 4-amino-5-methyl-4H-1,2,4-triasole-3-thion derivatives with diuretic activity

open access: yesZaporožskij Medicinskij Žurnal, 2018
1,2,4-Triazole derivatives have been widely used in medical practice due to their wide spectrum of biological activities and low toxicity, as they have 1,2,4-triazole cycle in their structure.
T. V. Kravchenko
doaj   +1 more source

Design, Hemiysnthesis, crystal structure and anticancer activity of 1, 2, 3-triazoles derivatives of totarol

open access: yesBioorganic Chemistry, 2021
A new series of diverse triazoles linked to the hydroxyl group of totarol were synthesized using click chemistry approach. The structures of these compounds were elucidated by HRMS, IR and NMR spectroscopy. The structure of compound 3 g was also confirmed by x-ray single crystal diffraction.
Laamari, Yassine   +9 more
openaire   +5 more sources

The synthesis of 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and its interaction with aldehydes

open access: yesЖурнал органічної та фармацевтичної хімії, 2021
Aim. To synthesize 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and study its reactivity in the reaction with aldehydes. Results and discussion.
D. М. Zozulynets   +2 more
doaj   +1 more source

Regioselective Synthesis of 1-(2,6-Dichloro-4-Trifluoromethylphenyl)- 4-Alkyl-1H-[1,2,3]-Triazoles

open access: yesMolecules, 2008
A new and efficient method for the synthesis of 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-alkyl-1H-[1,2,3]-triazoles by the room temperature 1,3-dipolarcycloaddition of (2-azido-1,3-dichloro-5-trifluoromethyl)benzene with terminal alkynes inthe presence
Lixue Zhang   +4 more
doaj   +1 more source

1,4-Disubstituted 1H-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties

open access: yesFrontiers in Chemistry, 2019
Peptidotriazolamers are hybrid foldamers with features of peptides and triazolamers, containing alternation of amide bonds and 1,4-disubstituted 1H-1,2,3-triazoles with conservation of the amino acid side chains. We report on the synthesis of a new class
David C. Schröder   +11 more
doaj   +1 more source

Synthesis methods of 1,2,4-triazole-3-thiones: review

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
1,2,4-Triazole-containing compounds are unique heterocyclic compounds present in an array of pharmaceuticals and biologically important compounds used in drug-discovery studies against cancer cells, microbes, and various types of diseases in the human ...
Yu. S. Frolova   +3 more
doaj   +1 more source

Effect of 4-benzylidenamino-5-phenyl-4Н-1,2,4-triazole-3-thiones and salts of 2-(4-amino-5-phenyl-4Н-1,2,4-triazole-3-ylthio)acetic acid on central component of nociceptive system

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Aim. To study the effect of 4-benzylideneamino-5-phenyl-4H-1,2,4-triazole-3-thiones and salts of 2-(4-amino-5-phenyl-4H-1,2,4-triazole-3-yltio)acetic acid on central component of nociceptive system on condition of thermal stimulation of limbs of rats ...
Ye. S. Pruhlo
doaj   +1 more source

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