Results 21 to 30 of about 13,314,497 (296)

Regioselective formation of new 3-S-alkylated-1,2,4-triazole-quinolones

open access: yes, 2021
Regioselective synthesis of quinolone-1,2,4-triazoles was established starting from 4-hydroxyquinol-2-ones. The strategy started by the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, which ...
Alan B. Brown (11775964)   +7 more
core   +1 more source

Synthesis, Transformations of Pyrrole- and 1,2,4-Triazole-Containing Ensembles, and Generation of Pyrrole-Substituted Triazole NHC

open access: yes, 2016
Unprecedented pyrrole- and 1,2,4-triazole-containing ensembles, substituted 1-(1H-pyrrol-3-yl)-4H-1,2,4-triazol-1-ium bromides and 4-(1H-pyrrol-3-yl)-1H-1,2,4-triazol-4-ium bromides, were prepared from 2H-azirines and triazolium phenacyl bromides using a
Alexander F. Khlebnikov (1537960)   +4 more
core   +2 more sources

1,3-Dipolar Cycloaddition Reactions of Substituted Benzyl Azides with Acetylenic Compounds

open access: yesMolecules, 2002
We review in this article some of our work which has been published over the last fifteen years in the area of 1,3-dipolar cycloaddition reactions of substituted benzyl azides with acetylenic compounds to form the corresponding 1,2-3-triazoles.
Sultan T. Abu-Orabi
doaj   +1 more source

Design, Hemiysnthesis, crystal structure and anticancer activity of 1, 2, 3-triazoles derivatives of totarol

open access: yesBioorganic Chemistry, 2021
A new series of diverse triazoles linked to the hydroxyl group of totarol were synthesized using click chemistry approach. The structures of these compounds were elucidated by HRMS, IR and NMR spectroscopy. The structure of compound 3 g was also confirmed by x-ray single crystal diffraction.
Laamari, Yassine   +9 more
openaire   +5 more sources

Quinolinyl Triazole Derivatives-Dominant Inhibitors for Mild Steel in Hydrochloric Acid [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2022
Quinolinyl triazole derivatives 4-(4-chlorophenyl)-5-{[(5-chloroquinolin-8-yl)oxy]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione (4-4CPCQMT), 4-(3-chlorophenyl)-5-{[(5-chloroquinolin-8-yl)oxy]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione (4-3CPCQMT) and
Nitin Kumar Shetty   +1 more
doaj   +1 more source

1,2,3-Triazole-Based Hybrids as EGFR Inhibitors: An overview [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences
Cancer continues to be a leading cause of mortality worldwide, presenting a major global public health concern. Despite advances in treatment, the discovery and development of effective anticancer drugs remain significant challenges for medicinal ...
Asmaa Yassen   +4 more
doaj   +1 more source

Metal Free Domino β‑Azidation/[3 + 2] Cycloaddition Reaction for the Synthesis of 1,2,3-Triazole-Fused Dihydrobenzoxazinones

open access: yes, 2019
A metal free DBU catalyzed synthesis of 1,2,3-triazole-fused dihydrobenzoxazinone derivatives by tandem β-azidation/[3 + 2] cycloaddition reaction has been developed under mild conditions.
Kiranmai Nayani (7148414)   +7 more
core   +2 more sources

The search for new 4-amino-5-methyl-4H-1,2,4-triasole-3-thion derivatives with diuretic activity

open access: yesZaporožskij Medicinskij Žurnal, 2018
1,2,4-Triazole derivatives have been widely used in medical practice due to their wide spectrum of biological activities and low toxicity, as they have 1,2,4-triazole cycle in their structure.
T. V. Kravchenko
doaj   +1 more source

The synthesis of 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and its interaction with aldehydes

open access: yesЖурнал органічної та фармацевтичної хімії, 2021
Aim. To synthesize 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and study its reactivity in the reaction with aldehydes. Results and discussion.
D. М. Zozulynets   +2 more
doaj   +1 more source

Chemodivergent Photocatalyzed Heterocyclization of Hydrazones and Isothiocyanates for the Selectivity Synthesis of 2‑Amino-1,3,4-thiadiazoles and 1,2,4-Triazole-3-thiones

open access: yes, 2023
A photocatalytic chemodivergent reaction for the selectivity formation of C–S and C–N bonds in a controlled manner was proposed. The reaction medium, either neutral or acidic, is critical to dictate the formation of 2-amino-1,3,4-thiadiazoles and 1,2,4 ...
Qing-Hu Teng   +9 more
core   +1 more source

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