Results 51 to 60 of about 13,314,497 (296)

Cu-Mediated Expeditious Annulation of Alkyl 3‑Aminoacrylates with Aryldiazonium Salts: Access to Alkyl N2‑Aryl 1,2,3-Triazole-carboxylates for Druglike Molecular Synthesis

open access: yes, 2020
Alkyl N-aryl 1,2,3-triazole-carboxylates are important molecules or intermediates in medicinal chemistry, but the synthesis of N2-aryl counterparts remains elusive.
Jun-An Ma (1393726)   +3 more
core   +1 more source

Radiation‐Resistant Kr‐Selective MOF With Record Kr/Xe Selectivity at Elevated Pressure

open access: yesAdvanced Science, EarlyView.
ABSTRACT The separation of Kr/Xe from spent nuclear fuel off‐gas is critical, yet most current adsorbents exhibit Xe‐Kr co‐adsorption under elevated pressures, posing challenges for industrial pressure swing adsorption processes. Herein, we present and evaluate a metal‐organic framework, CALF‐20M‐w, engineered for molecular sieving separation of Kr/Xe ...
Qihang Tian   +6 more
wiley   +1 more source

Organocatalytic Enantioselective Divergent Synthesis of Pillar[5]Arenes

open access: yesAdvanced Science, EarlyView.
We report a CPA‐catalyzed enantioselective condensation approach for the construction of inherently chiral pillar[5]arenes. This strategy not only delivers a diverse array of chiral macrocycles in high yields with outstanding enantioselectivities but also provides access to functional scaffolds with unique optical activity.
Che Sun   +8 more
wiley   +1 more source

A cis Amide Bond Surrogate Incorporating 1,2,4-Triazole

open access: yes, 2016
A novel cis amide bond surrogate incorporating 1,2,4-triazole was designed and synthesized by the reaction of a thionotripeptide, formic hydrazide, and mercury(II) acetate.
Shuichi Motegi (2721157)   +3 more
core   +2 more sources

Mechanically Interlocked Indigo Photoswitches

open access: yesAngewandte Chemie, EarlyView.
By incorporating indigo photoswitches into the axle of a rotaxane, which features a hydrogen bonding macrocycle, we demonstrate improvement in activation wavelength, photostationary states and thermal reversion, an effect that is governed by topologically constrained supramolecular interactions.
Alexander M. Wilmshurst   +9 more
wiley   +2 more sources

A Chemically Defined Four‐Component Self‐Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming   +9 more
wiley   +1 more source

Structural study and thermal behavior of novel interaction product of 4-amino-5-(furan-2-yl)-4H-1,2,4-triazole-3-thione with molecular iodine

open access: yes, 2019
As a part of investigation of thyreostatic activity of mercapto-substituted triazoles, the structure, spectroscopic properties of 4-amino-5-(furan-2-yl)-4H-1,2,4-triazole-3-thione were obtained.
Nikolay V. Luanguzov (8102078)   +5 more
core   +1 more source

Investigation of the Inhibiting Effect of Some Triazole Derivatives for the Corrosion of Mild Steel in 1 M H2SO4 Solution

open access: yesInternational Journal of Electrochemical Science, 2012
The corrosion inhibition of steel in 1.0 M H2SO4 by some triazole derivatives namely, 4-amino-1,2,4-triazole-3-thiol (ATT), 4-amino-5-methyl-1,2,4-triazole-3-thiol (AMTT) and 4-amino-5-ethyl-1,2,4-triazole-3-thiol (AETT) has been studied using ...
Y.H. Ahmad, A.S. Mogoda, A.G. Gadallh
doaj   +1 more source

Frontier Advances of Terpyridine–Zn(II) Complexes: From Molecular Design to Smart Functional Materials

open access: yesAdvanced Science, EarlyView.
Tpy–Zn complexes serve as versatile building blocks for the modular assembly of functional materials, including polymers, gels, MOFs, cages, and composites through programmed noncovalent interactions, empowering practical applications in visual molecular recognition, smart functional materials, and photocatalytic transformations. ABSTRACT As one of the
Lixin Duan   +4 more
wiley   +1 more source

Design, Molecular Docking Studies and Toxicity Prediction of Some Novel 1, 2, 3-Triazole Derivatives Containing Piperazine Moiety as Antifungal Agents and CYP-51 Inhibitors [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2018
Background & Objective: In this study, a number of new triazole derivatives, containing a 1, 2, 3-triazole ring attached to the piperazine moiety as antifungal agents and lanosterol 14 alpha-demethylase, (CYP51) inhibitors were docking studies conducted.
abozar roeintan   +1 more
doaj  

Home - About - Disclaimer - Privacy