Results 71 to 80 of about 47,847 (251)

Synthesis and Characterization of 1, 2, 3-Triazole Ligands and their Transition Metal Complexes [PDF]

, 2019
Click chemistry, an approach to synthesis using fast, versatile and high yielding reactions, has recently attracted attention as a simple way of preparing a wide scope of products. 1, 2, 3‐ triazoles can be prepared by Huisgen 1, 3‐ cycloaddition of azides and alkynes, where copper (I) as the catalyst dictates the formation of a 1, 4‐disubstituted ...
Perić, Berislav, Kirin, Srećko, Vianello, Robert, Pantalon Juraj, Natalija, Raić-Malić, Silvana, Novosel, Tiana   +5 more
openaire   +2 more sources

Features of the vegetative state and arterial pressure level in children with chronic gastroduodenal pathology

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Introduction. Heterocyclic compounds are the foundation on which the creation of medicines is successfully carried out. One such system is 1,2,4-triazole and 3-methylxanthine.
A. S. Hotsulia
doaj   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

Angewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini, Tania Pecoraro, Anna Lewinska, Maciej Wnuk, Olga Kolodziej, Daniela Intartaglia, Simona Morgera, Alessandro Aliprandi, Giulia Veronesi, Giorgio Facchetti, Isabella Rimoldi, Angela Tino, Claudia Tortiglione, Luisa De Cola   +13 more
wiley   +2 more sources

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +2 more sources

3-Nitro-1H-1,2,4-triazole

Acta Crystallographica Section E, 2011
The asymmetric unit of the title compound, C2H2N4O2, contains two crystallographically independent molecules in which the triazole rings are essentially planar, with maximum deviations of 0.003 (1) Å in both molecules.
Hoong-Kun Fun, Madhukar Hemamalini
doaj   +1 more source

Design, Synthesis and Anti-Lung Cancer Evaluation of 1, 2, 3-Triazole Tethered Dihydroartemisinin-Isatin Hybrids. [PDF]

Front Pharmacol, 2021
Hou H, Qu B, Su C, Hou G, Gao F.
europepmc   +1 more source

Evaluation of antioxidant activity of 1,2,4-triazole derivatives in the initiation of free radical processes

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
The activation of lipid free radical oxidation is a key stage in the development of many diseases and can lead to the emergence of related complications.
I. M. Bilai, V. I. Dariy, A. V. Khilkovets, A. I. Bilai, I. F. Duiun   +4 more
doaj   +1 more source

Cholinesterase Inhibitory Activity, Kinetic and Molecular Docking Studies of N-(1-substituted-1H-1,2,3-triazole-4-yl)-aralkylamide Derivatives

Walailak Journal of Science and Technology, 2016
Acetylcholinesterase (AChE) inhibitors are widely used for treatment of Alzheimer’s disease (AD). With the ultimate goal of improving the efficiency of AChE inhibitors currently used in AD treatment, in this study, a total number of 14 compounds of N-(1 ...
Woralak PETRAT, Chatchai WATTANAPIROMSAKUL, Teerapat NUALNOI, Nadia Hanim SABRI, Vannajan Sanghiran LEE LEE, Luelak LOMLIM   +5 more
doaj  

Synthesis and characterization of perfluorinated amphiphilic 1-2-3 triazoles compounds.

, 2021
Perflorlanmış amfifilik 1,2,3-triazol bileşiklerinin bir dizi analogları sentezlenmiştir. 2-perfloralkil-1-iodoetan başlangıç malzemeleri olarak kullanılmıştır.Çünkü metile protonlara perfloro grup denge bozucu etkisi nedeniyle, bu ürünlerin iyodürler arasında nükleofilik yer değiştirme kolayca gerçekleştirmektedir. Bununla birlikte, deney koşullarında
openaire   +1 more source