Results 81 to 90 of about 13,314,497 (296)

Auf dem Weg zu chromoselektiven Transformationen in biologischen Systemen: Perspektiven und Herausforderungen

open access: yesAngewandte Chemie, EarlyView.
Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley   +1 more source

Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine

open access: yesAngewandte Chemie, EarlyView.
A [3]rotaxane, composed by two crown ether macrocycles and an axle presenting three recognition sites, is operated through both chemical and electrochemical stimuli. The position of the macrocycles is precisely controlled by sequential stimulation and the processes are fully reversible. The characterization of the system revealed the macrocycles affect
Leonardo Andreoni   +3 more
wiley   +2 more sources

Synthesis, structure and properties of N-R-amides and hydrazides of 2-[4-R-5-(theophylline-7ʹ-yl)-1,2,4-triazole-3-ylthio]acetic acid

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
One of the most important tasks of modern pharmaceutical science is the search for new biologically active substances, which have high efficacy and low toxicity.
A. S. Gotsulya
doaj   +1 more source

α-Oximino-β-phenylhydrazones of Aroylacetarylamides and their Cyclisation into 1 ,2, 3-Triazoles

open access: yes, 1987
Chemistry Department, Sardar Patel University, VaMat& Vidyanagar-388 120 Manuscript received 7 February 1986, revised 31 March 1987, accepted 19 May 1987 A number of .α-oximino-β-phenylhydrazones of aroylacetarylamides have been synthesised. They were cyclised in thionyl chloride or acetic anhydride/sodium acetate to give 4-aryl-5-carboxy(aryIamino)
D. M. PATEL   +3 more
openaire   +2 more sources

Triazole-Containing [FeFe] Hydrogenase Mimics: Synthesis and Electrocatalytic Behavior

open access: yes, 2019
Through a Cu-catalyzed Huisgen cycloaddition between terminal alkynes and azides (CuAAC) reaction, azide [(μ-SCH2)2N­(4-N3C6H4)­Fe2(CO)6] has demonstrated to be a robust and versatile reagent able to incorporate the [(μ-SR)2Fe2(CO)6] fragment on a wide ...
Luis Casarrubios (1483762)   +7 more
core   +1 more source

1,2,4-Oxadiazoles from cycloreversions of oxadiazabicyclo[3.2.0]heptenes: 1-azetines as thiocyanate equivalents [PDF]

open access: yes, 2013
1,3-Dipolar cycloaddition of nitrile oxides to 4-aryl-2-alkylthio-1-azetines gave a series of oxadiazabicyclo[3.2.0]heptenes as single diastereoisomers. Heating these cycloadducts in toluene resulted in an overall [2+2]-cycloreversion to give 5-alkylthio-
Khan, Musharraf   +5 more
core   +1 more source

Phosphoryl Radicals from Trivalent Iminyl Phosphines: A Photocatalytic Approach to N‐Phosphoryl Azetidines

open access: yesAngewandte Chemie, EarlyView.
Photochemically generated phosphoryl radicals from iminyl phosphines enable strain‐release addition to azabicyclobutanes, providing access to elusive N‐phosphoryl azetidines. Combined experimental, computational, and EPR studies reveal an unconventional water‐assisted photoredox pathway.
Chandu G. Krishnan   +4 more
wiley   +2 more sources

Creation, study of physical and chemical properties of 2-((4-R-5-phenethyl-4H-1,2,4-triazole-3-yl)thio)ethanоic(propanоic, benzoic)acids and salts of 2-((4-R-5-phenethyl-4H-1,2,4-triazole-3-yl)thio)ethanoic acid

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
A large number of native and foreign scientists are involved in the synthesis of 3-thio-1,2,4-triazole. Today, a huge number of drugs based on 3-thio-1,2,4-triazole has been created, including itraconazole, fluconazole, voriconazole, letrozole ...
T. V. Ihnatova   +2 more
doaj   +1 more source

Synthesis of 2-(3-chloro-4-nitro-1-benzothien-2-yl)-1,3,4-oxadiazole-1,3,4-thiadiazole and 5-(3-chloro-4-nitro-1-benzothien-2-yl)-4H-1,2,4-triazole-3-thiol [PDF]

open access: yesمجلة التربية والعلم, 2010
In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole is reported. 3-chloro-4-nitro-2-chloro carbonyl benzo [b] thiophene(1) was synthesized from 2-nitrocinnamic acid by its reaction with thionyl chloride ...
Khalid M. Daoud   +2 more
doaj   +1 more source

Antimalarial activity of a novel series of artemisinin-derived 1, 2, 3-triazole dimers

open access: yesAsian Pacific Journal of Tropical Medicine, 2019
Objective: To obtain suitable artimisinin-based drug candidates with high antimalarial activity. Methods: Three different reaction schemes were used to synthesize a total of 15 artemisinin-based compounds. The first synthetic scheme involved the synthesis of diazido aliphatic and aromatic compounds from commercially available dihalides and azido ...
Kabita Gogoi   +6 more
openaire   +2 more sources

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