Results 111 to 120 of about 3,137,133 (371)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Child-raising, Childbirth and Abortion In Extremis: Women’s Stories of Caring for and Losing Children during the Violence of 1965–1966 in Indonesia

open access: yesJournal of Current Southeast Asian Affairs, 2013
In this paper I examine women survivors’ stories about childbirth and child-raising during the period of mass violence following Indonesia’s 1965 coup, as well as some accounts of abortion during detention.
Annie Pohlman
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

In Defense of Oral History: Evidence from the Mercosur Case En defensa de la Historia Oral: Evidencia del caso de Mercosur

open access: yesJournal of Politics in Latin America, 2012
This article makes a case in defense of oral history in the study of political science and international relations. The existing literature has scrutinized the technical aspects and appropriate use of oral material.
Gian Luca Gardini
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Kent, Lia (2012), The Dynamics of Transitional Justice: International Models and Local Realities in East Timor

open access: yesJournal of Current Southeast Asian Affairs, 2014
Book Review of the monograph: Kent, Lia (2012), The Dynamics of Transitional Justice: International Models and Local Realities in East Timor, Abingdon: Routledge (= Series: Transitional Justice), ISBN: 97804 15504362, 252 ...
Deniz Kocak
doaj  

Temperature dependent PL from SWNTs [PDF]

open access: yesarXiv, 2004
Photoluminescence (PL) and photoluminescence excitation (PLE) spectroscopy of pillar-suspended single-walled carbon nanotubes has been measured for temperatures between 300 K and 5 K.
arxiv  

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