Results 41 to 50 of about 10,175,510 (387)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Cabinets and Legislative Cartels in Uruguay: Examining the Legislative Consequences of Government Formation Gabinetes y Cárteles Legislativos en Uruguay: examen de las consecuencias legislativas de la formación del gobierno

Journal of Politics in Latin America, 2013
Since the return to democracy, Uruguayan presidents have built cabinets of varying natures (majority and minority coalitions, majority and minority parties).
Daniel Chasquetti
doaj  

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Myanmar in Contemporary Chinese Foreign Policy – Strengthening Common Ground, Managing Differences

Journal of Current Southeast Asian Affairs, 2012
This assessment first briefly examines recent features of China’s approach to foreign affairs, and then examines in greater detail features in China’s approach to relations with its neighbours, especially in Southeast Asia. It does so in order to discern
Robert Sutter
doaj  

Aging Behaviour and Mechanical Performance of 18-Ni 300 Steel Processed by Selective Laser Melting

, 2016
An 18-Ni 300 grade maraging steel was processed by selective laser melting and an investigation was carried out on microstructural and mechanical behaviour as a function of aging condition.
R. Casati, J. Lemke, A. Tuissi, M. Vedani   +3 more
semanticscholar   +1 more source

The state of Florida's estuaries and future needs in estuarine research: Part 2. an academic research agenda (review draft) [PDF]

, 1996
As a program supporting academic research that addresses recognized societal needs, the Florida Sea Grant Program is developing a research theme area on estuaries to provide a uniquely academic product that will augment mission-oriented research ...
Christie, Donna R., Kleppel, G.S., Milon, J. Walter, Smith, Ned P., Vargo, Gabriel A.   +4 more
core  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Preferences on Redistribution in Fragmented Labor Markets in Latin America and the Caribbean

Journal of Politics in Latin America, 2015
This study investigates the extent to which labor market dualization polarizes preferences on redistribution between formal and informal sector workers in Latin America and the Caribbean.
Sarah Berens
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Book Review: Hoffstaedter, Gerhard, Modern Muslim Identities: ...

Journal of Current Southeast Asian Affairs, 2012
Book Review of the monograph: Hoffstaedter, Gerhard (2011), Modern Muslim Identities: Negotiating Religion and Ethnicity in Malaysia Copenhagen: NIAS Press (= NIAS Monographs # 119), ISBN 978-87-7694-081-2, 304 ...
Holger Warnk
doaj