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miR-370-3p affects the progression of postmenopausal osteoporosis through targeting INO80 [PDF]

Hereditas
Background Postmenopausal osteoporosis (PMO) is acknowledged as a principal category of osteoporosis (OP). The aim of this study was to investigate the level of miR-370-3p in PMO patients and its predictive effect on osteoporosis in postmenopausal women,
Zhen Yang, Yuqi Sheng, Xiangjie Liu, Meini Cen, Yong Xu   +4 more
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miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4 [PDF]

Cells
The proliferation and maturation of hair follicles in follicular papilla cells are predominantly governed by miRNAs, which significantly influence the cell cycle, apoptosis, and proliferation.
Jiaqi Fu, Dan Wang, Wenqing Liu, Yu Qi, Caihong Zhang, Huansong Li, Jinshun Cai, Shuang Ji, Lichun Zhang, Fuliang Sun   +9 more
doaj   +2 more sources

48 or 370 to 1000 and More [PDF]

Structural Dynamics
Structure is of vital importance to structure-based drug design, significantly impacting both target selection and the rate of drug development. Increasing numbers of drug development portfolios, growing numbers of pharmaceutical and biotech companies ...
Lisa J. Keefe
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CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p [PDF]

Scientific Reports
Circular RNA (circRNA) is a unique closed ring structure of noncoding RNA. Although many human diseases have been confirmed to be inextricably linked with circRNAs, whether circRNAs have a potential regulatory function in the osteogenic differentiation ...
Lei Zhang, Yidan Xu, Ningning Liu, Mengjie Xu, Refeina Tuerxun, Mireyeti Shahatibieke, Yuan Yao   +6 more
doaj   +2 more sources

Preliminary Report of Non-punitive Reporting of Perioperative Adverse Events in Peking Union Medical College Hospital during 2010—2014

Xiehe Yixue Zazhi, 2021
Objective  o optimize the system conditions and improve the patients' perioperative surgical safety through feedback learning for adverse events.  Methods  We retrospectively analyzed the adverse events (AEs) and risks of patients' safety reported by the
ZHU Bo, ZHANG Yu, FENG Xuexin, ZHANG Xiuhua, HUANG Yuguang   +4 more
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Serum exosomal microRNA-370-3p and microRNA-196a-5p are potential biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

Folia Histochemica et Cytobiologica, 2022
INTRODUCTION: Evidence has shown that some microRNAs (miRNAs) play a role in tumorigenesis of hepatocellular carcinoma (HCC). Herein, we aimed to evaluate the diagnostic and prognostic values of serum exosomal miR-370-3p and miR-196a-5p in patients with ...
Yaning Wei, Qian Zhang, Lin An, Guotao Fang, Dan Hong, Ting Jiao, Hua Yang, Zhiyu Wang   +7 more
doaj   +1 more source

MiR-370-3P inhibits proliferation of human articular chondrocytes by regulating JAK2/STAT5B signaling pathway

Di-san junyi daxue xuebao, 2021
Objective To investigate whether the non-coding single chain RNA miR-370-3P regulates the proliferation of human articular chondrocytes (HC-a) through the JAK2/STAT5B signaling pathway and to explore its potential mechanism.
CHEN Lanni, ZHANG Huijiao, XU Xuejiao, XU Ke, ZHU Min   +4 more
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Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars

Scientific Reports, 2022
Aromatic rice (Oryza sativa) fetches a premium price due to the pleasant aroma. The major aroma compound 2-acetyl-1-pyrroline (2AP) has been found to be enhanced under stress.
N. Renuka, Vitthal T. Barvkar, Zahid Ansari, Chunfang Zhao, Cailin Wang, Yadong Zhang, Altafhusain B. Nadaf   +6 more
doaj   +1 more source

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes

Journal of Integrative Agriculture, 2023
In mammals, microRNAs (miRNAs) play key roles in multiple biological processes by regulating the expression of target genes. Studies have found that the levels of miR-370-5p expression differ significantly in the skins of sheep with different hair colors;
Kai-yuan JI, Ru-jun WEN, Zheng-zhou WANG, Qian-qian TIAN, Wei ZHANG, Yun-hai ZHANG   +5 more
doaj   +1 more source

miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5

Stem Cells International, 2021
miRNAs play a crucial part in multiple biological processes of cell proliferation, migration, apoptosis, and chemoresistance. In cancer, miRNAs can be divided into oncogenes or tumor suppressors on the basis of their functions in the carcinogenic process.
Jiahui Mao, Lingxia Wang, Junying Wu, Yichun Wang, Huiyan Wen, Xueming Zhu, Bo Wang, Huan Yang   +7 more
doaj   +1 more source