Results 11 to 20 of about 2,364,113 (288)

miR-370-3p affects the progression of postmenopausal osteoporosis through targeting INO80 [PDF]

open access: yesHereditas
Background Postmenopausal osteoporosis (PMO) is acknowledged as a principal category of osteoporosis (OP). The aim of this study was to investigate the level of miR-370-3p in PMO patients and its predictive effect on osteoporosis in postmenopausal women,
Zhen Yang   +4 more
doaj   +2 more sources

48 or 370 to 1000 and More [PDF]

open access: yesStructural Dynamics
Structure is of vital importance to structure-based drug design, significantly impacting both target selection and the rate of drug development. Increasing numbers of drug development portfolios, growing numbers of pharmaceutical and biotech companies ...
Lisa J. Keefe
doaj   +2 more sources

Preliminary Report of Non-punitive Reporting of Perioperative Adverse Events in Peking Union Medical College Hospital during 2010—2014

open access: yesXiehe Yixue Zazhi, 2021
Objective  o optimize the system conditions and improve the patients' perioperative surgical safety through feedback learning for adverse events.  Methods  We retrospectively analyzed the adverse events (AEs) and risks of patients' safety reported by the
ZHU Bo   +4 more
doaj   +1 more source

Serum exosomal microRNA-370-3p and microRNA-196a-5p are potential biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

open access: yesFolia Histochemica et Cytobiologica, 2022
INTRODUCTION: Evidence has shown that some microRNAs (miRNAs) play a role in tumorigenesis of hepatocellular carcinoma (HCC). Herein, we aimed to evaluate the diagnostic and prognostic values of serum exosomal miR-370-3p and miR-196a-5p in patients with ...
Yaning Wei   +7 more
doaj   +1 more source

Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars

open access: yesScientific Reports, 2022
Aromatic rice (Oryza sativa) fetches a premium price due to the pleasant aroma. The major aroma compound 2-acetyl-1-pyrroline (2AP) has been found to be enhanced under stress.
N. Renuka   +6 more
doaj   +1 more source

MiR-370-3P inhibits proliferation of human articular chondrocytes by regulating JAK2/STAT5B signaling pathway

open access: yesDi-san junyi daxue xuebao, 2021
Objective To investigate whether the non-coding single chain RNA miR-370-3P regulates the proliferation of human articular chondrocytes (HC-a) through the JAK2/STAT5B signaling pathway and to explore its potential mechanism.
CHEN Lanni   +4 more
doaj   +1 more source

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes

open access: yesJournal of Integrative Agriculture, 2023
In mammals, microRNAs (miRNAs) play key roles in multiple biological processes by regulating the expression of target genes. Studies have found that the levels of miR-370-5p expression differ significantly in the skins of sheep with different hair colors;
Kai-yuan JI   +5 more
doaj   +1 more source

miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5

open access: yesStem Cells International, 2021
miRNAs play a crucial part in multiple biological processes of cell proliferation, migration, apoptosis, and chemoresistance. In cancer, miRNAs can be divided into oncogenes or tumor suppressors on the basis of their functions in the carcinogenic process.
Jiahui Mao   +7 more
doaj   +1 more source

Neuraminidase (NA) 370-Loop Mutations of the 2009 Pandemic H1N1 Viruses Affect NA Enzyme Activity, Hemagglutination Titer, Mouse Virulence, and Inactivated-Virus Immunogenicity

open access: yesViruses, 2022
Hemagglutinin (HA) and neuraminidase (NA) are the two major envelope proteins of influenza viruses. The spatial organization of HA and NA on the virus surface needs to be optimized to promote viral fitness, host specificity, transmissibility, infectivity,
Ting-Hsuan Chen   +2 more
doaj   +1 more source

MiR‐370 accelerated cerebral ischemia reperfusion injury via targeting SIRT6 and regulating Nrf2/ARE signal pathway

open access: yesKaohsiung Journal of Medical Sciences, 2020
Cerebral ischemia reperfusion (CIR) is one of the highly lethal diseases in the world. MicroRNA‐370 (miR‐370) exerts multiple functions in different diseases. However, further research is needed to investigate the potential role of miR‐370 in CIR injury.
Zhong‐Fan Ruan   +5 more
doaj   +1 more source

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