Results 11 to 20 of about 298,990 (289)

miR-370-3p Regulates Adipogenesis through Targeting Mknk1

Molecules, 2021
Excessive fat accumulation can lead to obesity, diabetes, hyperlipidemia, atherosclerosis, and other diseases. MicroRNAs are a class of microRNAs that regulate gene expression and are highly conserved in function among species.
Peiwen Zhang, Xinrong Li, Shunhua Zhang, Shuang Wu, Qian Xiao, Yang Gu, Xinyu Guo, Xutao Lin, Lei Chen, Ye Zhao, Lili Niu, Guoqing Tang, Yanzhi Jiang, Linyuan Shen, Li Zhu   +14 more
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MiR‐370 accelerated cerebral ischemia reperfusion injury via targeting SIRT6 and regulating Nrf2/ARE signal pathway

Kaohsiung Journal of Medical Sciences, 2020
Cerebral ischemia reperfusion (CIR) is one of the highly lethal diseases in the world. MicroRNA‐370 (miR‐370) exerts multiple functions in different diseases. However, further research is needed to investigate the potential role of miR‐370 in CIR injury.
Zhong‐Fan Ruan, Ming Xie, Shu‐Jia Gui, Fang Lan, Juan Wan, Yan Li   +5 more
doaj   +1 more source

Silencing of miR-370 in human cholangiocarcinoma by allelic loss and interleukin-6 induced maternal to paternal epigenotype switch. [PDF]

PLoS ONE, 2012
Cholangiocarcinoma (CCA) is a highly lethal malignant tumor arising from the biliary tract epithelium. Interleukin-6 (IL-6) is a major mediator of inflammation and contributor to carcinogenesis within the biliary tree.
Fangmei An, Sumitaka Yamanaka, Sarah Allen, Lewis R Roberts, Gregory J Gores, Timothy M Pawlik, Qing Xie, Masaharu Ishida, Esteban Mezey, Anne C Ferguson-Smith, Yuriko Mori, Florin M Selaru   +11 more
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miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker

Molecular Therapy: Nucleic Acids, 2018
In the last decade, microRNAs (miRs) have been described as biomarkers and therapeutic agents. Based on this finding, our aim here is to know if (1) miRNA-370-3p can be used as a biomarker associated with a favorable survival and if (2) miRNA-370-3p can ...
Arulraj Nadaradjane, Joséphine Briand, Gwenola Bougras-Cartron, Valentine Disdero, François M. Vallette, Jean-Sébastien Frenel, Pierre-François Cartron   +6 more
doaj   +1 more source

Neuraminidase (NA) 370-Loop Mutations of the 2009 Pandemic H1N1 Viruses Affect NA Enzyme Activity, Hemagglutination Titer, Mouse Virulence, and Inactivated-Virus Immunogenicity

Viruses, 2022
Hemagglutinin (HA) and neuraminidase (NA) are the two major envelope proteins of influenza viruses. The spatial organization of HA and NA on the virus surface needs to be optimized to promote viral fitness, host specificity, transmissibility, infectivity,
Ting-Hsuan Chen, Chung-Chu Chen, Suh-Chin Wu   +2 more
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MicroRNA-370 inhibits the proliferation, invasion and EMT of gastric cancer cells by directly targeting PAQR4

Journal of Pharmacological Sciences, 2018
It has been reported that PAQR4 (Progestin and AdipoQ Receptor 4) expression is closely associated with progression of many cancers and microRNA (miRNA) processing.
Ye Feng, Tao Sun, Yabo Yu, Yongjian Gao, Xuefeng Wang, Zhi Chen   +5 more
doaj   +1 more source

Circ_0035292 knockdown alleviates lipopolysaccharide (LPS)‐induced WI‐38 cell apoptosis and inflammatory injury

Immunity, Inflammation and Disease, 2023
Background Circular RNAs have emerged as important regulators in the pathogenesis of human diseases, including infantile pneumonia (IP). In this study, we aimed to explore the effects of circ_0035292 on lipopolysaccharide (LPS)‐treated Wistsar Institute (
Ying Guo, Zhouzhen Li, Chen Cheng
doaj   +1 more source

The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia

Molecular Cancer, 2012
Background Recent evidence has accumulated that MicroRNA (miRNA) dysregulation occurs in the majority of human malignancies including acute myeloid leukemia (AML) and may contribute to onco-/leukemo-genesis.
Zhang Xiaolu, Zeng Jiping, Zhou Minran, Li Bingnan, Zhang Yuanyuan, Huang Tao, Wang Lixiang, Jia Jihui, Chen Chunyan   +8 more
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Extramedullary Acute Leukemia—Still an Unforeseen Presentation

Hematology Reports, 2022
Myeloid sarcomas (MS) are rare extramedullary (EM) hematological tumors that generally arise during the natural course of acute myeloid leukemia (AML), occurring concomitantly with the onset of systemic leukemia; it can also occur following onset but ...
Dina Rochate, Carolina Pavão, Rui Amaral, Carolina Viveiros, José Cabeçadas, Vitor Carneiro, Cristina Fraga   +6 more
doaj   +1 more source

Circ_002117 binds to microRNA-370 and promotes endoplasmic reticulum stress-induced apoptosis in gastric cancer

Cancer Cell International, 2020
Background Mounting evidence implicates circular RNAs (circRNAs) in various biological processes during cancer progression. Gastric cancer is a main cause of cancer-related deaths worldwide.
Nan Zhou, Hui Qiao, Miaomiao Zeng, Lei Yang, Yongning Zhou, Quanlin Guan   +5 more
doaj   +1 more source