Results 21 to 30 of about 607,065 (259)
Frontiers in Oncology, 2022 Traditional studies using cancer cell lines are often performed on a two-dimensional (2D) cell culture model with a low success rate of translating to Phase I or Phase II clinical studies. In comparison, with the advent of developments three-dimensional (
Huaikai Shi +26 more
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Mesenchymal stem cells lose the senescent phenotype under 3D cultivation
Stem Cell Research & Therapy, 2023 Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment ...
O. Krasnova +8 more
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Cells, 2023 Background: Three-dimensional cell culture systems hold great promise for bridging the gap between in vitro cell-based model systems and small animal models to study tissue biology and disease.
Mariangela Scalise +15 more
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3D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications
Frontiers in Cardiovascular Medicine, 2019 Three-dimensional (3D) cell culture is often mentioned in the context of regenerative medicine, for example, for the replacement of ischemic myocardium with tissue-engineered muscle constructs.
Christian Zuppinger
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Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer.
PLoS ONE, 2019 PURPOSE:Two-dimensional (2D) cell culture is a valuable method for cell-based research but can provide unpredictable, misleading data about in vivo responses.
Myeong Joo Kim +5 more
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Magnetic Stiffening in 3D Cell Culture Matrices [PDF]
Nano Letters, 2021 The mechanical environment of a cell is not constant. This dynamic behavior is exceedingly difficult to capture in (synthetic) in vitro matrices. This paper describes a novel, highly adaptive hybrid hydrogel composed of magnetically sensitive magnetite nanorods and a stress-responsive synthetic matrix. Nanorod rearrangement after application of (small)
Wen Chen +4 more
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Current Approaches to Three-Dimensional Cell Culture System
Namık Kemal Tıp Dergisi, 2020 Two-dimensional (2D) cell culture is a valuable method for cell-based research, However, it may provide unpredictable, misleading data on in vivo responses.
Elif POLAT
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The Use of Biomaterials in Three-Dimensional Culturing of Cancer Cells
Current Issues in Molecular Biology, 2023 Cell culture is an important tool in biological research. Most studies use 2D cell culture, but cells grown in 2D cell culture have drawbacks, including limited cell and cell-extracellular matrix interactions, which make it inaccurate to model conditions
Novia Hanasti +5 more
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3D Cell Culture Models of Epithelial Tissues [PDF]
, 2019 Cells in tissues in vivo face a very different microenvironment than typical cultured cells plated on a plastic dish. Already several decades ago, cell biologists observed that cell lines show dramatically different morphology and growth characteristics when embedded into three-dimensional (3D) substrates or standard tissue culture plates (Montesano R,
Manninen Aki, Zhang Kai
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3D cell culture model: From ground experiment to microgravity study
Frontiers in Bioengineering and Biotechnology, 2023 Microgravity has been shown to induce many changes in cell growth and differentiation due to offloading the gravitational strain normally exerted on cells.
Chiyuan Ma +4 more
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