Results 21 to 30 of about 10,293,161 (301)

Different Expression of Thyroid-Specific Proteins in Thyroid Cancer Cells between 2-Dimensional (2D) and 3-Dimensional (3D) Culture Environment

Cells, 2022
The two-dimensional (2D) monolayer culture as a conventional method has been widely applied in molecular biology fields, but it has limited capability to recapitulate real cell environments, being prone to misinterpretation with poor prediction of in ...
Ji Min Oh, Prakash Gangadaran, Ramya Lakshmi Rajendran, Chae Moon Hong, Jaetae Lee, Byeong-Cheol Ahn   +5 more
doaj   +1 more source

A miniaturized bioreactor system for the evaluation of cell interaction with designed substrates in perfusion culture [PDF]

, 2011
In tissue engineering, the chemical and topographical cues within three-dimensional (3D) scaffolds are normally tested using static cell cultures but applied directly to tissue cultures in perfusion bioreactors.
M. O. Riehle, J.R. Higginson (7130108), Higginson, J.R., Donoghue, P.S., T. Sun, Nikolaj Gadegaard (1292763), J. R. Higginson, N. Gadegaard, Riehle, M.O., Mathis O. Riehle (1292769), Barnett, S.C., Sun, T., Tao Sun (1255119), Peter S. Donoghue (7128581), S. C. Barnett, Gadegaard, N., P. S. Donoghue, Susan C. Barnett (7128590)   +17 more
core   +1 more source

Muscle injury-induced hypoxia alters the proliferation and differentiation potentials of muscle resident stromal cells

Skeletal Muscle, 2019
Background Trauma-induced heterotopic ossification (HO) is a complication that develops under three conditions: the presence of an osteogenic progenitor cell, an inducing factor, and a permissive environment. We previously showed that a mouse multipotent
Geneviève Drouin, Vanessa Couture, Marc-Antoine Lauzon, Frédéric Balg, Nathalie Faucheux, Guillaume Grenier   +5 more
doaj   +1 more source

Mesenchymal stem cells lose the senescent phenotype under 3D cultivation

Stem Cell Research & Therapy, 2023
Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment ...
O. Krasnova, A. Kovaleva, A. Saveleva, K. Kulakova, O. Bystrova, M. Martynova, A. Domnina, J. Sopova, I. Neganova   +8 more
doaj   +1 more source

3-Dimensional mesothelioma spheroids provide closer to natural pathophysiological tumor microenvironment for drug response studies

Frontiers in Oncology, 2022
Traditional studies using cancer cell lines are often performed on a two-dimensional (2D) cell culture model with a low success rate of translating to Phase I or Phase II clinical studies. In comparison, with the advent of developments three-dimensional (
Huaikai Shi, Emma M. Rath, Ruby C. Y. Lin, Ruby C. Y. Lin, Ruby C. Y. Lin, Kadir Harun Sarun, Candice Julie Clarke, Brian C. McCaughan, Brian C. McCaughan, Helen Ke, Helen Ke, Anthony Linton, Anthony Linton, Anthony Linton, Kenneth Lee, Kenneth Lee, Sonja Klebe, Sonja Klebe, Joanneke Maitz, Joanneke Maitz, Joanneke Maitz, Kedong Song, Yiwei Wang, Yiwei Wang, Steven Kao, Steven Kao, Yuen Yee Cheng   +26 more
doaj   +1 more source

Microtubules in 3D cell motility [PDF]

, 2017
Three-dimensional (3D) cell motility underlies essential processes, such as embryonic development, tissue repair and immune surveillance, and is involved in cancer progression. Although the cytoskeleton is a well-studied regulator of cell migration, most
Sub Cell Biology, Celbiologie, Anna Akhmanova, Bouchet, Benjamin P, Benjamin P. Bouchet, Akhmanova, Anna   +5 more
core   +1 more source

Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer.

PLoS ONE, 2019
PURPOSE:Two-dimensional (2D) cell culture is a valuable method for cell-based research but can provide unpredictable, misleading data about in vivo responses.
Myeong Joo Kim, Byung Hoon Chi, James J Yoo, Young Min Ju, Young Mi Whang, In Ho Chang   +5 more
doaj   +1 more source

Adult Multipotent Cardiac Progenitor-Derived Spheroids: A Reproducible Model of In Vitro Cardiomyocyte Commitment and Specification

Cells, 2023
Background: Three-dimensional cell culture systems hold great promise for bridging the gap between in vitro cell-based model systems and small animal models to study tissue biology and disease.
Mariangela Scalise, Fabiola Marino, Luca Salerno, Nunzia Amato, Claudia Quercia, Chiara Siracusa, Andrea Filardo, Antonio Chiefalo, Loredana Pagano, Giuseppe Misdea, Nadia Salerno, Antonella De Angelis, Konrad Urbanek, Giuseppe Viglietto, Daniele Torella, Eleonora Cianflone   +15 more
doaj   +1 more source

Current Approaches to Three-Dimensional Cell Culture System

Namık Kemal Tıp Dergisi, 2020
Two-dimensional (2D) cell culture is a valuable method for cell-based research, However, it may provide unpredictable, misleading data on in vivo responses.
Elif POLAT
doaj   +1 more source

The Use of Biomaterials in Three-Dimensional Culturing of Cancer Cells

Current Issues in Molecular Biology, 2023
Cell culture is an important tool in biological research. Most studies use 2D cell culture, but cells grown in 2D cell culture have drawbacks, including limited cell and cell-extracellular matrix interactions, which make it inaccurate to model conditions
Novia Hanasti, Lia Faridah, Azzania Fibriani, Hesti Lina Wiraswati, Diah Kusumawaty, Savira Ekawardhani   +5 more
doaj   +1 more source