Results 31 to 40 of about 10,804,267 (253)

A Three-Dimensional Co-Culture Model for Rheumatoid Arthritis Pannus Tissue

Frontiers in Bioengineering and Biotechnology, 2021
Three-dimensional (3D) co-culture models have closer physiological cell composition and behavior than traditional 2D culture. They exhibit pharmacological effects like in vivo responses, and therefore serve as a high-throughput drug screening model to ...
Jietao Lin, Jietao Lin, Jietao Lin, Antonia RuJia Sun, Antonia RuJia Sun, Antonia RuJia Sun, Jian Li, Jian Li, Jian Li, Tianying Yuan, Wenxiang Cheng, Wenxiang Cheng, Wenxiang Cheng, Liqing Ke, Liqing Ke, Liqing Ke, Jianhai Chen, Jianhai Chen, Jianhai Chen, Wei Sun, Shengli Mi, Peng Zhang, Peng Zhang, Peng Zhang   +23 more
doaj   +1 more source

Self-assembling peptide hydrogels : directing cell behaviour by chemical composition [PDF]

, 2008
Over recent years, there has been a growing interest in the design of self-assembly systems using aromatic short peptide derivatives for biomedical applications including 3D cell culture.
Richardson, S. M., Gough, J., Jayawarna, V., Ulijn, R.   +3 more
core   +5 more sources

Mechanobiology-based strategies for the maturation of biofabricated cartilage constructs

Frontiers in Bioengineering and Biotechnology
Recent advancements in 3D bioprinting and biofabrication offer promising avenues for tissue engineering (TE) and regenerative medicine (RM), particularly in addressing musculoskeletal conditions such as articular cartilage lesions.
Iván López-González, Iván López-González, Noelia Campillo, José Manuel Baena, José Manuel Baena, José Manuel Baena   +5 more
doaj   +1 more source

Organotypic 3D Cell-Architecture Impacts the Expression Pattern of miRNAs–mRNAs Network in Breast Cancer SKBR3 Cells

Non-Coding RNA, 2023
Background. Currently, most of the research on breast cancer has been carried out in conventional two-dimensional (2D) cell cultures due to its practical benefits, however, the three-dimensional (3D) cell culture is becoming the model of choice in cancer
María de los Ángeles Gastélum-López, Maribel Aguilar-Medina, Cristina García Mata, Jorge López-Gutiérrez, Geovanni Romero-Quintana, Mercedes Bermúdez, Mariana Avendaño-Felix, César López-Camarillo, Carlos Pérez-Plascencia, Adriana S Beltrán, Rosalío Ramos-Payán   +10 more
doaj   +1 more source

Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system

, 2023
Orbital shaker-based suspension culture systems have been in widespread use for differentiating human pluripotent stem cell (hPSC)-derived pancreatic progenitors toward islet-like clusters during endocrine induction stages.
Zhan, Lisa, Timothy J. Kieffer, Jia Zhao, Robert K. Baker, Baker, Robert K, Elisa Tran, Zhao, Jia, Shenghui Liang, Tran, Elisa, Lisa Zhan, Liang, Shenghui, Kieffer, Timothy J   +11 more
core   +1 more source

Multiple cystic sphere formation from PK-8 cells in three-dimensional culture

Biochemistry and Biophysics Reports, 2022
Three-dimensional (3D) culture of cancer cells mimics the in vivo environment. Recently, we reported that pancreatic ductal adenocarcinoma (PDAC) cell lines with epithelial and mesenchymal features formed differently shaped spheres in 3D culture. However,
Yuuki Shichi, Fujiya Gomi, Yoshibumi Ueda, Keisuke Nonaka, Fumio Hasegawa, Yasuko Hasegawa, Nae Hinata, Hisashi Yoshimura, Masami Yamamoto, Kimimasa Takahashi, Tomio Arai, Toshiyuki Ishiwata   +11 more
doaj   +1 more source

3D Cell Culture Models of Epithelial Tissues [PDF]

, 2019
Cells in tissues in vivo face a very different microenvironment than typical cultured cells plated on a plastic dish. Already several decades ago, cell biologists observed that cell lines show dramatically different morphology and growth characteristics ...
Kai Zhang, Aki Manninen, Manninen, Aki, Zhang, Kai   +3 more
core   +1 more source

Novel 3D-Printed Cell Culture Inserts for Air–Liquid Interface Cell Culture

, 2022
In skin research, widely used in vitro 2D monolayer models do not sufficiently mimic physiological properties. To replace, reduce, and refine animal experimentation in the spirit of ‘3Rs’, new approaches such as 3D skin equivalents (SE) are needed to ...
Marvin Corea, Magdalena Metzger, Schädl, Barbara, Grillari, Johannes, Dungel, Peter, Peter Dungel, Johannes Grillari, Bauer, Magdalena, Barbara Schädl, Metzger, Magdalena, Corea, Marvin, Magdalena Bauer   +11 more
core   +1 more source

Simplified One-stop Protocols to Extract Collagen from Various Animal Tissues for 3D Cell Cultures [PDF]

, 2020
In this manuscript, we present a one-stop protocol to extract collagen from various animal tissues, and apply it to fabricate 3D cell culture ...
Chengpeng, Chen, John A., Terrell
core   +1 more source

3D CULTURE OF HaCaT KERATINOCYTE CELL LINE AS AN in vitro TOXICITY MODEL

Trakya University Journal of Natural Sciences, 2022
Ex vivo dermal toxicology analyses are crucial for replacement of in vivo test methods and have been of interest in recent years for testing cosmetics, drugs, and chemicals.
Fikrettin Şahin, Engin Sümer, Burçin Asutay, Derya Sağraç, Hatice Burcu Şişli, Binnur Kıratlı, Taha Bartu Hayal, Derya Burukçu, Selinay Şenkal, Ayşegül Doğan   +9 more
doaj   +1 more source