Results 1 to 10 of about 617,736 (147)
Cells, 2020 Much interest has been directed towards stem cells, both in basic and translational research, to understand basic stem cell biology and to develop new therapies for many disorders.
Joni H. Ylostalo
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The challenge of ovarian tissue culture: 2D versus 3D culture [PDF]
Journal of Ovarian Research, 2021 Background Cryopreservation of ovarian tissue is a powerful technique for preserving female fertility, as it can restore fertility and endocrine function.
Ana Sofia Pais +6 more
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Validation of a novel perfusion bioreactor system in cancer research [PDF]
Hemijska Industrija, 2020 Development of drugs is a complex, time- and cost-consuming process due to the lack of standardized and reliable characterization techniques and models. Traditionally, drug screening is based on in vitro analysis using two-dimensional (2D) cell cultures ...
Stojkovska Jasmina +5 more
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médecine/sciences, 2021 Le dossier que nous présentons a été rédigé par les étudiantes et étudiants de Master 1 de Biologie de l’École normale supérieure de Lyon à l’issue de l’UE Microbiologie moléculaire et structurale (2020-2021). Le Master de biologie de l’ENS de Lyon accueille chaque année environ 40 étudiants en M1 et en M2 et propose une formation de haut niveau à la ...
Eliès Froment, Sarah Erraiss
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Negative regulation of CDKN1A by the histone methyltransferase EHMT2 for cell growth in colorectal cancer [PDF]
Organoid, 2022 Background Epigenetic regulation of oncogenes and tumor suppressor genes by histone methyltransferases is an important process for colon cancer growth and metastasis.
Kwangho Kim +3 more
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Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model
Nanomaterials, 2020 (1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures.
Elisabeth Elje +7 more
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Cell culture models for SARS-CoV-2 infectivity and systemic complications [PDF]
Pharmaceutical Sciences Asia, 2022 COVID-19 was declared by WHO as a pandemic since March 2020. The vaccination program has been implemented worldwide. Specific antiviral drugs such as remdesivir, molnupiravir and ritonavir-based nirmatrelvir were effective against SARS-CoV-2 infection ...
Khanit Sa-ngiamsuntorn +3 more
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Intracellular Ca2+ Responses of 3D-Cultured Osteoblasts to Dynamic Loading
Journal of Biomechanical Science and Engineering, 2012 In bone cells, intracellular Ca2+ (iCa2+) functions as a second messenger in the mechanotransduction pathway. Its responses to mechanical stimulation can be observed microscopically on a rigid flat surface with a Ca2+ fluorescent indicator, generally ...
Shigeo M. TANAKA
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Implementation of an in vitro exposure system for 28 GHz
ETRI Journal, 2020 The objective of this study was to implement an in vitro exposure system for 28 GHz to investigate the biological effects of fifth‐generation (5G) communication. A signal source of 28 GHz for 5G millimeter‐wave (MMW) deployment was developed, followed by
Young Seung Lee +7 more
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Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms
Molecules, 2020 Human induced pluripotent stem cells (hiPSCs) have transformed conventional drug discovery pathways in recent years. In particular, recent advances in hiPSC biology, including organoid technologies, have highlighted a new potential for neural drug ...
Agustín Cota-Coronado +4 more
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