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Implementing Culture of Care in Germany [PDF]
AnimalsThe implementation of the 3Rs principles is an essential part of daily routines and structural processes in animal research. The work of Russell and Burch regarding the 3Rs has been implemented in the field over the course of decades, but since 2002, the
Katharina Ameli, Stephanie Krämer
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The 3Rs applied to fruits and vegetables surpluses: virtuous examples from Italy
Food Materials Research, 2023 When facing environmental issues associated with food waste, it is necessary to look upstream at the root causes. At the very beginning of the supply chain, there is the first cause of waste generation: unrecovered agriculture surpluses.
Francesca Girotto, Laura Piazza
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Animals, 2023 Based on the current state of science, the use of animals remains essential in bringing safe and effective medicines to patients. Respect for laboratory animal welfare and the application of 3Rs principles (the replacement, reduction, and refinement of ...
Jessica C. Graham +6 more
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Open Veterinary Journal, 2023 Background: Vaccination is widely used in fish aquaculture for three primary reasons: to prevent bacterial disease spreading, minimize antibiotic use and fight antibiotic resistance.
Antonella Di-Paolo +4 more
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Reporting of 3Rs Approaches in Preclinical Animal Experimental Studies—A Nationwide Study
Animals, 2023 The 3Rs aim to refine animal welfare, reduce animal numbers, and replace animal experiments. Investigations disclose that researchers are positive towards 3Rs recommendations from peers.
Birgitte S. Kousholt +6 more
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Journal of Immunotoxicology, 2021 Sensitization to a contact allergen brings with it a lifelong risk to develop allergic contact dermatitis. Inflammation is an important part of the skin sensitizing mechanism, and understanding how different haptens stimulate the immune system, as well ...
Venkatanaidu Karri +4 more
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The Case for Modernizing Biomedical Research in Ireland through the Creation of an Irish 3Rs Centre
Animals, 2022 Since its publication, the 3Rs principle has provided a cornerstone for more ethical and humane biomedical and regulatory research. In Europe, the 3Rs principle has been incorporated into the European Directive 63/2010/EU, with the ultimate aim of fully ...
Viola Galligioni +4 more
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Advancing the 3Rs: innovation, implementation, ethics and society
Frontiers in Veterinary Science, 2023 The 3Rs principle of replacing, reducing and refining the use of animals in science has been gaining widespread support in the international research community and appears in transnational legislation such as the European Directive 2010/63/EU, a number ...
Herwig Grimm +12 more
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Expert Review of Vaccines, 2023 Introduction Potency is a critical quality attribute for controlling quality consistency and relevant biological properties of vaccines. Owing to the high demand for animals, lengthy operations and high variability of in vivo methods, in vitro ...
Xuanxuan Zhang +6 more
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The principle of the 3Rs between aspiration and reality
Frontiers in Physiology, 2022 The Principle of the 3Rs is widely recognised as the methodological and ethical backbone of contemporary animal research. Different authors also stress the reciprocal links among the 3Rs, and how these often complement and reinforce each other.
Augusto Vitale, Laura Ricceri
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