Results 111 to 120 of about 9,574 (212)

Long‐Term Low‐Dose of Nitrate Administration Improves Antioxidant Defence System in Insulin‐Sensitive Tissues of Type 2 Diabetic Rats

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Long‐term nitrate administration at low doses has a protective effect against oxidative stress in the liver, soleus muscle (SM) and epididymal adipose tissue (eAT) of male rats with type 2 diabetes (T2D). ABSTRACT Introduction Type 2 diabetes (T2D) is characterised by increased oxidative stress, which contributes to insulin resistance in insulin ...
Fatemeh Ghorbani, Majid Shokri, Sajad Jeddi, Asghar Ghasemi   +3 more
wiley   +1 more source

Noninvasive 11.7‐T Magnetic Resonance Spectroscopy and Imaging Reveals Retinal Metabolic Alterations Induced by Blue Light Exposure

NMR in Biomedicine, Volume 39, Issue 3, March 2026.
Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila, Alexandru Farcasanu, Simion Simon, Ede Bodoki, Ovidiu Samoila, Oliviu Vostinaru, Elena Dinte, Andreea Elena Bodoki, Dan Iudean, Calin Muresan, Simona Clichici   +10 more
wiley   +1 more source

Comparing training methods to promote better animal welfare outcomes for animals in the research and teaching industry. [PDF]

Anim Welf
Cohen S, Lomax S, Hemsworth L, Tripovich JS, Slavich E, Brandis KJ, Becker JA.   +6 more
europepmc   +1 more source

Acepromazine Reduces Airway Contraction in a Murine Model of Asthma

Clinical and Experimental Pharmacology and Physiology, Volume 53, Issue 3, March 2026.
ABSTRACT Acepromazine (ACP) is one of the most used sedatives in veterinary medicine, and its cardiovascular effects are well documented. In contrast, its effects on the respiratory system remain less well understood, particularly in the context of assessment of respiratory mechanics in murine models of asthma, where its use has become more common in ...
Alembert Lino‐Alvarado, Maria Aparecida de Oliveira, Carmen Silvia Moreno Serra, Isabella Victoria Santana Melhado, Rafael Campos, Yanira Riffo‐Vasquez, Henrique Takachi Moriya   +6 more
wiley   +1 more source

Animal models of critical illness in the Asia-Pacific region: current practices, shared challenges, and future directions. [PDF]

Intensive Care Med Exp
Fujinami Y, Liu S, Bassi GL, Osuchowski M, Yao Y, Fraser J, Inoue S.   +6 more
europepmc   +1 more source

A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice

Aging Cell, Volume 25, Issue 3, March 2026.
A gut‐derived metabolic signature drives systemic aging phenotypes. Integrated multi‐omics profiling of young versus aged mice identifies a conserved aging signature characterized by the depletion of protective lysophosphatidylcholines (LPC 22:0) and the concurrent accumulation of pro‐oxidative microbial catabolites (TMAO, IAA).
Sanaullah Sajid, Jieliang Huang, Shaofang Kong, Chengze Lai, Zhuoxin Tan, Yiming Shao, Lianxian Guo   +6 more
wiley   +1 more source

Hippo Pathway Drives Durable Non‐Cell‐Autonomous Ferroptosis Resistance in Lung Cancer

Cancer Science, Volume 117, Issue 3, Page 683-694, March 2026.
YAP/TAZ, key effectors in lung cancer progression, paradoxically sensitize tumor cells to ferroptosis. This study reveals that YAP/TAZ‐low cells confer non‐cell‐autonomous, GCH1‐mediated durable ferroptosis resistance to neighboring YAP/TAZ‐high cells via a soluble factor, highlighting a Hippo pathway‐linked mechanism of tumor adaptation and survival ...
Mohamed Fathi Saleh, Akihiro Nita, Yudai Ohta, Aya Kobayashi, Hao Li, Yasuhisa Sakamoto, Toshiro Moroishi   +6 more
wiley   +1 more source

Building resilience in animal research: a two-year mixed methods survey of organizational support programs. [PDF]

Front Vet Sci
Young L, Thompson-Iritani S, Bellanca RU, Ferrara F, Bell K, Martin T, LaFollette MR.   +6 more
europepmc   +1 more source

Preclinical Evaluation of the Effect of Liquid Platelet–Rich Fibrin and a Volume‐Stable Collagen Matrix on Periodontal Regeneration

Journal of Clinical Periodontology, Volume 53, Issue 3, Page 424-435, March 2026.
ABSTRACT Aim To evaluate the regenerative potential of liquid platelet–rich fibrin (PRF), with and without a volume‐stable collagen matrix (VCMX), in periodontal intrabony defects using histological, histometric and micro‐CT analyses. Materials and Methods One‐wall intrabony defects were surgically created in six beagle dogs and treated with either ...
Jean‐Claude Imber, Andrea Roccuzzo, Nikola Saulacic, Maria Permuy Mendaña, Sıla Cagrı Isler, Dieter D. Bosshardt, Anton Sculean, Alexandra Stähli   +7 more
wiley   +1 more source

The Status and Emerging Developments in Laboratory Animal Science in Asia since 9th AFLAS Congress (2023) until 10th AFLAS Congress (2025). [PDF]

Animal Model Exp Med
Asian Federation of Laboratory Animal Science Associations (AFLAS).
europepmc   +1 more source