Results 31 to 40 of about 9,574 (212)
Advanced Healthcare Materials, EarlyView.This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney +3 more
wiley +1 more source
Supporting the 3Rs worldwide: The 3Rs Database program
Biomedical Science and Engineering, 2021 Our 3Rs databases and informative websites facilitate the implementation of 3Rs methods.
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
3R,1R or 3R + 1R? The Teachers’ Dilemma
Procedia - Social and Behavioral Sciences, 2010 AbstractThe aim of education should be character building, and it begins with education of the heart. Hence, teachers in schools play a very important role in encouraging student to value diversity and regard it as an asset or resource, rather than a liability or problem. How is the situation with teachers in Malaysian school?
Liu, Ong Puay +3 more
openaire +1 more source
Advanced Healthcare Materials, EarlyView.This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre +3 more
wiley +1 more source
Improving Guest and Owner Satisfaction through a Circular Economy: An Agritourism Case Study
Tourism and HospitalityThis study examines the role of agritourism in developing strategies to promote a circular economy by applying the 3Rs (reduce, reuse, and recycle) and improving guests’ satisfaction.
Paula Tavares de Carvalho +2 more
doaj +1 more source
Researchers' attitudes to the 3Rs-An upturned hierarchy? [PDF]
PLoS ONE, 2018 Animal use in biomedical research is generally justified by its potential benefits to the health of humans, or other animals, or the environment. However, ethical acceptability also requires scientists to limit harm to animals in their research. Training
Nuno Henrique Franco +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang +13 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani +7 more
wiley +1 more source
Implementation of the 3Rs Concept in Quality Control of Biologicals: Status and Prospects (Review)
Безопасность и риск фармакотерапииINTRODUCTION. Many countries are implementing an increasing number of alternatives to animal testing in the research, development, and quality control of medicines under the concept of 3Rs (replacement, reduction, and refinement).
L. A. Gaiderova +5 more
doaj +1 more source