Results 41 to 50 of about 9,574 (212)

3Rs Principle and Legislative Decrees to Achieve High Standard of Animal Research

Animals, 2023
Animal experimentation is a vast ecosystem that tries to make different issues such as legislative, ethical and scientific coexist. Research in animal experimentation has made many strides thanks to the 3Rs principle and the attached legislative decrees,
Paolo Verderio, Mara Lecchi, Chiara Maura Ciniselli, Bjorn Shishmani, Giovanni Apolone, Giacomo Manenti   +5 more
doaj   +1 more source

Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes

Advanced Materials, EarlyView.
Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar, Shahrokh Vahabi, Elena Bellotti, Martina Corsi, Irene Nocera, Paola Orlandi, Guido Bocci, Giuseppe Barillaro   +7 more
wiley   +1 more source

Exploring resilience capacities with food innovators: a narrative approach

Global Sustainability, 2020
We interviewed grassroots food innovators in South Africa to explore the diverse ways in which their narratives expressed different capacities for resilience, such as dealing with surprise and shaping desirable change. We drew on key resilience themes of
Megan Lindow, Rika Preiser, Reinette Biggs   +2 more
doaj   +1 more source

Aggression in Group-Housed Male Mice: A Systematic Review

Animals, 2022
Aggression among group-housed male mice is a major animal welfare concern often observed at animal facilities. Studies designed to understand the causes of male mice aggression have used different methodological approaches and have been heterogeneous ...
Elin M. Weber, Josefina Zidar, Birgit Ewaldsson, Kaisa Askevik, Eva Udén, Emma Svensk, Elin Törnqvist   +6 more
doaj   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Restoration of Degraded Tropical Peatland in Indonesia: A Review

Land, 2021
Tropical peatlands are fragile ecosystems with an important role in conserving biodiversity, water quality and availability, preventing floods, soil intrusion, erosion and sedimentation, and providing a livelihood for people.
Tri Wira Yuwati, Dony Rachmanadi, Pratiwi, Maman Turjaman, Yonky Indrajaya, Hunggul Yudono Setio Hadi Nugroho, Muhammad Abdul Qirom, Budi Hadi Narendra, Bondan Winarno, Sri Lestari, Purwanto Budi Santosa, Rahardyan Nugroho Adi, Endang Savitri, Pamungkas Buana Putra, Reni Setyo Wahyuningtyas, Retno Prayudyaningsih, Wawan Halwany, Besri Nasrul, Bastoni, Daniel Mendham   +19 more
doaj   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Swiss 3R Competence Centre: Promoting the 3Rs implementation

Biomedical Science and Engineering, 2020
This contribution describes the history and activity of the Swiss 3R Competence Centre (3RCC), which has been founded in 2018. Among the most relevant activities, a call for project proposals on 3Rs was launched in 2018, with 47 proposals received for selection, followed by a call for nominations for a 3Rs award, which will be announced in Sept.
openaire   +2 more sources

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

The rise of Generative AI and possible effects on the economy

Economics and Business Review, 2023
The aim of the paper is to analyse the likely implications of Generative AI (GAI) on various aspects of business and the economy. Amid the rapid growth and maturing of Generative AI technologies such as Large Language Models (like ChatGPT by OpenAI) a ...
Orchard Tim, Tasiemski Leszek
doaj   +1 more source