Results 151 to 160 of about 58,354 (259)

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil   +6 more
wiley   +1 more source

Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang   +4 more
wiley   +1 more source

Trisoxazole Macrolides Potentiate the Microtubule Assembly and Antimitotic Activities of Taxanes

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Photoaffinity experiments identified tubulin as a new target of mycalolides. Though weakly cytotoxic, the trisoxazole macrolactone moiety enhanced paclitaxel's microtubule assembly and antimitotic effects. Molecular modeling studies suggested that MyC stabilizes α/β‐tubulin heterodimer interactions.
Shohei Ebihara   +4 more
wiley   +2 more sources

Sustainable Applications of Thymol: Advances in Formulation Technologies, Drug Delivery Systems, and Food Preservation Strategies

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Thymol is a natural monoterpene with antimicrobial, antioxidant, anti‐inflammatory, and anticancer activities relevant to food and biomedical applications. Its poor solubility and instability can be improved through nanodelivery systems. Thymol also supports sustainable food preservation and active packaging, although further clinical validation and ...
Farhang Hameed Awlqadr   +8 more
wiley   +1 more source

EVI1 mediated stimulation of 3T3-L1 preadipocyte differentiation is CtBP dependent [PDF]

open access: yes, 2017
Al-Hasan, M.   +4 more
core   +1 more source

Solvent‐Dependent Biological Activities of Aqueous and Ethanolic Extracts From Edible Insect Larvae

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
This study compares the functional activity profiles of aqueous and ethanolic extracts from edible insect larvae. Solvent‐dependent extraction resulted in distinct bioactivity patterns, highlighting the importance of extraction conditions in determining the functional potential of insect‐derived bioactive compounds.
Min‐Cheol Kang   +9 more
wiley   +1 more source

The Eubacterium Rectale Derived Extracellular Vesicles Alleviate Cancer Cachexia Induced Lipolysis by Inhibiting Macrophage Polarization

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Cancer cachexia (CC) is a complex pathological condition associated with cancer progression and poor prognosis, particularly in gastrointestinal cancers, and is closely linked to the gut microbiota. Lipolysis in CC may play a key role in driving cachexia progression.
Jiaqi Wang   +11 more
wiley   +1 more source

The effects and mechanisms of saponins of panax notoginseng on glucose and lipid metabolism in 3T3-L1 cells [PDF]

open access: yes, 2008
University of Technology, Sydney. Faculty of Science.NO FULL TEXT AVAILABLE. Access is restricted indefinitely. The hardcopy may be available for consultation at the UTS Library.NO FULL TEXT AVAILABLE. Access is restricted indefinitely.
Kim, JJY
core  

Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan   +8 more
wiley   +1 more source

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley   +1 more source

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