Results 11 to 20 of about 21,834 (203)

4-Aminopyridine treatment for nerve injury resulting from radical retro-pubic prostatectomy: a single-center double-blind, randomized, placebo-controlled study [PDF]

open access: yesTrials
Background Prostate cancer (PCa) is the most common non-cutaneous malignancy in men and leads to the second most common cause of cancer related mortality in men. Early detection of PCa allows for a potentially curative intervention.
Ahmed Ghazi   +4 more
doaj   +2 more sources

PHOTOACTINIC IRRADIATION EFFECT ON REFRACTION INDICE OF ORGANIC CO-CRYSTALS BASED ON AMINOPYRIDINE SERIES [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2020
Subject of Research. The paper presents research of photoactinic radiation effect on refractive indice of organic nonlinear optical co-crystals: 2.6-diaminopyridine-4-nitrophenol and 4-aminopyridine-4-nitrophenol. Method. The research technique included
Kirill E. Zhevaikin   +2 more
doaj   +1 more source

4-aminopyridine – the new old drug for the treatment of neurodegenerative diseases [PDF]

open access: yesPharmacia, 2019
In this review are described the preclinical and clinical pharmacological data as well as new therapeutic indications for the use of 4-aminopyridine.
Ivanka Kostadinova, Nikolai Danchev
doaj   +3 more sources

Synthesis of 2-aminopyridine Lactones and Studies of Their Antioxidant, Antibacterial and Antifungal Properties

open access: yesChemistry Proceedings, 2021
In the present work, the synthesis and biological activities of substituted 2-aminopyridine δ-lactone derivatives were achieved. 4,6,6-trimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile was synthesised from 4-hydroxy-4-methylpentan-2-one, followed by ...
Fadila Salhi   +3 more
doaj   +1 more source

4-Aminopyridine — A Review [PDF]

open access: yesAnaesthesia and Intensive Care, 1982
4-aminopyridine is the first of the aminopyridines to be used in clinical practice. It blocks potassium channels and thereby increases acetylcholine, and possibly noradrenaline, release at nerve terminals. In man the drug has a significant action at the neuromuscular junction, but has little effect on the autonomic nervous system or muscle (smooth ...
N, Soni, P, Kam
openaire   +2 more sources

4-Aminopyridine Decreases MPTP-Induced Behavioral Disturbances in Animal Model of Parkinson’s Disease

open access: yesInternational Clinical Neuroscience Journal, 2015
Background and purpose: Progressive degeneration of dopaminergic neurons in the midbrain is the main mechanism of Parkinson’s disease (PD). Although potassium channels affect neural activity and death in this area, little research has investigated the ...
Reza Taherian, Mehran Arab Ahmadi
doaj   +1 more source

The crystal structure of poly[bis(μ2−3−aminopyridine−4−carboxylato−κ2N:O)Zinc(II)], [Zn(C6H5N2O2)2]n

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2023
[Zn(C6H5N2O2)2${({\mathrm{C}}_{6}{\mathrm{H}}_{5}{\mathrm{N}}_{2}{\mathrm{O}}_{2})}_{2}$]n, orthorhombic, P212121 (no. 19), a = 7.6139(7) Å, b = 12.4890(13) Å, c = 13.9382(13) Å, V = 1325.4(2) Å3, Z = 4, Rgt(F) = 0.0391, wRref(F2) = 0.0710, T = 296 K.
Liu Fang-Fang   +3 more
doaj   +1 more source

Convulsant actions of 4-aminopyridine on the guinea-pig olfactory cortex slice [PDF]

open access: yes, 1982
The effects of bath-applied 4-aminopyridine on neurones and extracellular potassium and calcium concentrations were recorded in slices of guinea-pig olfactory cortex. Neurones were orthodromically activated by stimulating the lateral olfactory tract.
Baranyi   +47 more
core   +1 more source

4-Aminopyridinium azide 4-aminopyridine solvate

open access: yesActa Crystallographica Section E, 2010
In the title compound, C5H7N2+·N3−·C5H6N2, all N atoms of the azide anion are situated on a twofold rotational axis, so the 4-aminopyridinium cation and 4-aminopyridine molecule, being related by symmetry, occupy one position ...
Hui-Fen Qian, Wei Huang
doaj   +1 more source

Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]

open access: yes, 1980
Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri   +36 more
core   +1 more source

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