Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]
Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri +36 more
core +1 more source
Hydroxyapatite and Silicon-Modified Hydroxyapatite as Drug Carriers for 4-Aminopyridine
Adsorption and desorption properties of nano-hydroxyapatite (HAP) and silicon-modified hydroxyapatite (Si–HAP) were investigated with 4-aminopyridine (fampridine-4AP). The novelty of this research is the investigation of the suitability of the previously
Laura Marincaș +7 more
doaj +1 more source
BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga +4 more
doaj +3 more sources
Synthesis and Characterization of Palladium (II) Complexes With Some Pyridine Derivatives
Complexes of palladium (II) with pyridine derivatives in general formula: trans- [PdCl2L1 2], (where: L1 = 2- picoline, 3- picoline, 4- picoline); [pd L1 4](BF4) 2, (Where: L1=3-picoline, 4-picoline); trans- [PdCl2L2 2] and [pd L2 4] (BF4) 2, (Where: L2
M. J. Al-Jeboori +2 more
doaj +1 more source
Dynamic walking features and improved walking performance in multiple sclerosis patients treated with fampridine (4-aminopyridine) [PDF]
Background: Impaired walking capacity is a frequent confinement in Multiple Sclerosis (MS). Patients are affected by limitations in coordination, walking speed and the distance they may cover.
A Chetta +29 more
core +2 more sources
Enantioselective Total Synthesis of Macfarlandin C, a Spongian Diterpenoid Harboring a Concave-Substituted cis-Dioxabicyclo[3.3.0]octanone Fragment. [PDF]
The enantioselective total synthesis of the rearranged spongian diterpenoid (-)-macfarlandin C is reported. This is the first synthesis of a rearranged spongian diterpenoid in which the bulky hydrocarbon fragment is joined via a quaternary carbon to the ...
Allred, Tyler K +4 more
core +2 more sources
Phosphoric acid doped polysulfone membranes with aminopyridine pendant groups and imidazole cross-links [PDF]
Udel polysulfone based membranes with 4-aminopyridine pendant groups and cross-linking imidazole units are synthesized in a simple two step reaction. The ratio of 4-aminopyridine and imidazole is varied and the materials are extensively characterized ...
Cleemann, Lars Nilausen +8 more
core +1 more source
Effects of 4- Aminopyridine on Inflammatory Reactions in Experimental Models [PDF]
Background And Aim : Nowadays, many inflammatory diseases such as rheumatoid arthritis (RA) and Multiple sclerosis (MS) and many other autoimmune inflammatory diseases has involved the people of different communities and cure for them so far has not been
SA Mirshafyei +6 more
doaj +2 more sources
Redetermination of para-aminopyridine (fampridine, EL-970) at 150 K [PDF]
The structure of fampridine (EL-970) or 4-aminopyridine, C₅H₆N₂, has been redetermined at 150 K. The room-temperature structure has been reported previously [Chao & Schempp (1977). Acta Cryst. B33, 1557-1564]. Pyramidalization at the amine N atom occurs
Anderson, Frankie P. +3 more
core +1 more source
Twisted Intramolecular Charge Transfer in Protonated Amino Pyridine [PDF]
International audienceThe excited state properties of protonated ortho (2-), meta (3-) and para (4-) aminopyridine molecules have been investigated through UV photo fragmentation spectroscopy and excited state couple cluster CC2 calculations.
Broquier, Michel +5 more
core +4 more sources

