Hydroxyapatite and Silicon-Modified Hydroxyapatite as Drug Carriers for 4-Aminopyridine
Crystals, 2021 Adsorption and desorption properties of nano-hydroxyapatite (HAP) and silicon-modified hydroxyapatite (Si–HAP) were investigated with 4-aminopyridine (fampridine-4AP). The novelty of this research is the investigation of the suitability of the previously
Laura Marincaș +7 more
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Phosphoric acid doped polysulfone membranes with aminopyridine pendant groups and imidazole cross-links [PDF]
, 2015 Udel polysulfone based membranes with 4-aminopyridine pendant groups and cross-linking imidazole units are synthesized in a simple two step reaction. The ratio of 4-aminopyridine and imidazole is varied and the materials are extensively characterized ...
Cleemann, Lars Nilausen +8 more
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Revista Brasileira de Anestesiologia, 2015 BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga +4 more
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Synthesis and Characterization of Palladium (II) Complexes With Some Pyridine Derivatives
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2008 Complexes of palladium (II) with pyridine derivatives in general formula: trans- [PdCl2L1 2], (where: L1 = 2- picoline, 3- picoline, 4- picoline); [pd L1 4](BF4) 2, (Where: L1=3-picoline, 4-picoline); trans- [PdCl2L2 2] and [pd L2 4] (BF4) 2, (Where: L2
M. J. Al-Jeboori +2 more
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Dynamic walking features and improved walking performance in multiple sclerosis patients treated with fampridine (4-aminopyridine) [PDF]
, 2015 Background: Impaired walking capacity is a frequent confinement in Multiple Sclerosis (MS). Patients are affected by limitations in coordination, walking speed and the distance they may cover.
A Chetta +29 more
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Redetermination of para-aminopyridine (fampridine, EL-970) at 150 K [PDF]
, 2005 The structure of fampridine (EL-970) or 4-aminopyridine, C₅H₆N₂, has been redetermined at 150 K. The room-temperature structure has been reported previously [Chao & Schempp (1977). Acta Cryst. B33, 1557-1564]. Pyramidalization at the amine N atom occurs
Anderson, Frankie P. +3 more
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Effects of 4- Aminopyridine on Inflammatory Reactions in Experimental Models [PDF]
پیاورد سلامت, 2009 Background And Aim : Nowadays, many inflammatory diseases such as rheumatoid arthritis (RA) and Multiple sclerosis (MS) and many other autoimmune inflammatory diseases has involved the people of different communities and cure for them so far has not been
SA Mirshafyei +6 more
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Twisted Intramolecular Charge Transfer in Protonated Amino Pyridine [PDF]
, 2016 International audienceThe excited state properties of protonated ortho (2-), meta (3-) and para (4-) aminopyridine molecules have been investigated through UV photo fragmentation spectroscopy and excited state couple cluster CC2 calculations.
Broquier, Michel +5 more
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Abnormal Action Potentials Associated with the Shaker Complex Locus of Drosophila [PDF]
, 1981 Intracellular recordings of action potentials were made from the cervical giant axon in Shaker (Sh) mutants and normal Drosophila. The mutants showed abnormally long delays in repolarization.
Ferrus, Alberto +2 more
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4-Aminopyridine inhibits the neuromuscular effects of nitric oxide and 8-Br-cGMP
Brazilian Journal of Medical and Biological Research, 2003 The effects induced by nitric oxide (NO) in different tissues depend on direct and/or indirect interactions with K+ channels. The indirect interaction of NO is produced by activation of guanylyl cyclase which increases the intracellular cGMP.
R.N. Queiroz +2 more
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