Results 131 to 140 of about 3,474 (171)
THE INTERACTIONS. OF 4-NITROQUINOLINE-1-OXIDE WITH FOUR DEOXYRIBONUCLEOTIDES
, 1977 openaire +1 more source
Inhibition of 4-nitroquinoline-1-oxide genotoxicity by Bacillus strains [PDF]
Research in Microbiology, 2002 The effect of 16 Bacillus strains from pharmaceutical probiotic preparations (Bacillus spp.) and collection (B. subtilis, B. firmus, B. megaterium, B. pumilus) on genotoxicity induced by the known mutagen 4-nitroquinoline-1-oxide (4-NQO) was studied using the short-term bacterial assay SOS-chromotest.
Giovanni Cenci
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Interactions of 4-nitroquinoline 1-oxide with deoxyribodinucleotides
Biochemistry, 1979The interactions of 4-nitroquinoline 1-oxide (NQO), a potent mutagen and carcinogen, with several self- and non-self-complementary deoxydinucleotides were probed by using absorption spectra of the charge transfer bands and 1H and 13C NMR spectra. Absorption spectra were analyzed by using Benesi-Hildebrand-type equations to yield stoichiometries and ...
S A, Winkle, I, Tinoco
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Mutagenicity of 4-nitroquinoline 1-oxide in the Muta™Mouse
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 1999As part of a collaborative study, the Mammalian Mutagenesis Study Group (MMS), a sub-organization of the Environmental Mutagen Society of Japan (JEMS) conducted mutagenicity tests in MutaMouse. Using a positive selection method, we studied the organ-specificity and time dependence of mutation induction by 4-nitroquinoline 1-oxide (4NQO).
M, Nakajima +8 more
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Toxicity of 4‐Nitroquinoline 1‐Oxide for Crithidia fasciculata
The Journal of Protozoology, 1975SYNOPSISGrowth inhibition of Crithidia fasciculata by 4‐nitroquinoline 1‐oxide (NQO) was observed in defined and complex media at 28 C. Aromatic amino acids, cysteine, and nicotinic acid, among several other substances, were ineffective in overcoming NQO toxicity. Dicoumarol and bovine albumin reversed NQO inhibition.
W, Leon, F S, Cruz, M E, Vasconcellos
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Molecular Biology of the Carcinogen, 4-Nitroquinoline 1-Oxide
1976Publisher Summary Studies on chemical carcinogenesis have three main purposes. First is to elucidate carcinogenic mechanisms, second is to prevent possible carcinogenic hazard due to chemicals in the environment, and third is to provide clinical model systems in experimental animals. Recent studies on chemical carcinogens and mutagens have shown that,
M, Nagao, T, Sugimura
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4 Nitroquinoline 1‐oxide‐induced carcinogenesis in the rat palate
Journal of Oral Pathology & Medicine, 1983Most reported studies of experimental oral cancer have been carried out in the hamster. This animal is not available in certain countries and there is controversy regarding its suitability as a model for experimental oral carcinogenesis. An attempt was made to reproduce an experimental oral cancer model in rats, using a protocol based on that described
P N, Wong, D F, Wilson
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4-Nitroquinoline-1-oxide induced experimental oral carcinogenesis
Oral Oncology, 2006Human oral cancer is the sixth largest group of malignancies worldwide and single largest group of malignancies in the Indian subcontinent. Seventy percent of premalignant cancers appear from premalignant lesions. Only 8-10% of these lesions finally turn into malignancy. The appearance of these premalignant lesions is one distinct feature of human oral
Deepak, Kanojia, Milind M, Vaidya
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In vitro transformation of hamster chondrocytes by 4-nitroquinoline 1-oxide
Cancer Letters, 1976Hamster sternal chondrocytes were transfored morphologically in vitro 29-51 days after exposure to 4-nitroquinoline 1-oxide for 3 h. The transformed chondrocytes were randomly oriented, piled up and grew continuously. These cells produced nodules when transferred to the cheek pouch of a hamster.
Y, Katoh, S, Takayama
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