Results 101 to 110 of about 5,266 (185)

Design, synthesis and antiproliferative, apoptotic, and immunomodulatory properties of new heteroaryl pyridine-linked 1,2,4-oxadiazoles as prospective dual EGFR/BRAF^V600E inhibitors. [PDF]

RSC Adv
Gomaa HAM, Shaker ME, Alzarea SI, Alatwi E, Mohamed FAM, Abdullah Alzahrani AY, Alyami BA, Bräse S, Rabea SM, Youssif BGM.   +9 more
europepmc   +1 more source

Novel pyrazole-oxadiazole-chalcone/oxime hybrids as dual EGFR/VEGFR-2 inhibitors with promising anticancer potential: a comprehensive cytotoxicity evaluation, mechanistic insights and SAR analysis. [PDF]

Mol Divers
Alshazly O, Abdel-Aziz M, Abuo-Rahma GEA, Mohamed MFA.   +3 more
europepmc   +1 more source

Lonidamine-1,3,4-oxadiazole derivatives with antiproliferative effects on HCT116 colon cancer cell lines: biological evaluation, ADMET, and computational studies. [PDF]

RSC Adv
Bhat RM, Priyadarshini AN, Sudhanva MS, Muddapur GV, Alhussieni K, K RK, Keri RS.   +6 more
europepmc   +1 more source

Design, synthesis and antiproliferative activity of oxadiazole derivatives as potent glycogen synthase kinase-3/histone deacetylase 6 dual inhibitors. [PDF]

J Enzyme Inhib Med Chem
Ye C, Chen Z, Jiang J, Li J, Kong R, Liu S, Chen X, Xu Z.   +7 more
europepmc   +1 more source

Bridging mechanism and design: modern medicinal chemistry approaches to thymidylate synthase inhibitors. [PDF]

RSC Adv
Al-Karmalawy AA, Eissa ME, Yousef TA, Al Khatib AO, Hawas SS.   +4 more
europepmc   +1 more source

Exploring 1,3,4-oxadiazolyl sulfide derivatives as antidiabetic candidates: synthesis, antioxidant activity, SAR-study, molecular docking, and DFT-insights. [PDF]

BMC Chem
Khalaf NA, Said GE, Abdel-Latif E, Metwally HM.   +3 more
europepmc   +1 more source

Novel Imidazopyridine-Oxadiazole β‑Tubulin Inhibitors Suppress Breast Cancer Migration and Induce Caspase-3-Mediated Apoptosis. [PDF]

ACS Omega
Cakir M, Kuzu B.
europepmc   +1 more source

Effect of 1,3,4-oxadiazoles on expression of biofilm-associated bap gene in clinical isolates of multidrug-resistant Acinetobacter baumannii. [PDF]

Sci Rep
Rahimbakhsh A, Seyfahmadi M, Souldozi A, Hakimelahi R, Alikhani MY, Kafilzadeh F.   +5 more
europepmc   +1 more source

Lead Optimization: Synthesis and Biological Evaluation of Griseofulvin Derivatives as Novel SIRT6 Activators. [PDF]

ACS Med Chem Lett
Zorko T, Kogovšek J, Ciber L, Ostojić I, Maraš N, Novinec M, Štefane B.   +6 more
europepmc   +1 more source

Synthesis & Biological Evaluation of 1, 3, 4- Oxadiazoles as Anticancer Agents

Indo Global Journal of Pharmaceutical Sciences, 2015
Suryanarayana Raju D, T.N.V. Ganesh Kumar, Jesil Mathew, null Jeyaprakash, Ajit Kandale, Rajeev K Singla   +5 more
openaire   +1 more source