Results 101 to 110 of about 12,853,470 (222)

Synthesis, Characterization & Biological Evaluation of Some Novel 1, 3, 4-Oxadiazole Derivatives [PDF]

, 2019
Substituted oxadiazole, 5-(2-hydroxyphenyl)-1, 3, 4-oxadiazole-2(3H)-thione was synthesized from salicylic acid. The titled oxadiazole derivatives were synthesized by making substitution at free N-(3H) position of 5-(2-hydroxyphenyl)-1, 3, 4 ...
Abirami, A V
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Investigation of 1, 3, 4 Oxadiazole Derivative in PTZ-Induced Neurodegeneration: A Simulation and Molecular Approach. [PDF]

J Inflamm Res, 2021
Faheem M, Althobaiti YS, Khan AW, Ullah A, Ali SH, Ilyas U.   +5 more
europepmc   +1 more source

Computational Investigation of 1, 3, 4 Oxadiazole Derivatives as Lead Inhibitors of VEGFR 2 in Comparison with EGFR: Density Functional Theory, Molecular Docking and Molecular Dynamics Simulation Studies. [PDF]

Biomolecules, 2022
Bilal MS, Ejaz SA, Zargar S, Akhtar N, Wani TA, Riaz N, Aborode AT, Siddique F, Altwaijry N, Alkahtani HM, Umar HI.   +10 more
europepmc   +1 more source

Synthesis and Characterization of New 1,3,4-Oxadiazole Derivatives from Sulfathiazole [PDF]

المجلة العراقية للصيدلة
Background: Oxadiazole are important heterocyclic compounds in organic chemistry. Methods: In this work, a series of new 1,3,4-oxadiazole moiety started from diazonium salt was synthesized.
Jassim Jassim, Aws Nejres, Laith Atiyah, Hussein Ibrahim, Zeyad Hameed   +4 more
doaj   +1 more source

Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide. [PDF]

Res Pharm Sci, 2021
Hassanzadeh F, Jafari E, Shojaei F, Sadeghi-Aliabadi H.   +3 more
europepmc   +1 more source

3,4-Bis(4-nitrophenyl)-1,2,5-oxadiazole 2-oxide

, 2008
The title compound, C14H8N4O6, a new 1,2,5-oxadiazole N-oxide derivative, was formed by dimerization of 4-nitrobenzaldehyde oxime. The compound crystallizes with two independent molecules per asymmetric unit.
Najib Ben Larbi, Abdelali Kerbal, Ghali Alhouari, Helen Stoeckli-Evans, Maria Daoudi, Taibi Ben Hadda   +5 more
core   +1 more source

3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

Pharmaceuticals
Background: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease with global implications, necessitating effective management strategies.
Tatiana V. Zinevich, Ivan O. Maslov, Olga G. Kirichenko, Sergey V. Shorshnev, Maxim A. Gureev, Fedor M. Dolgushin, Yuri B. Porozov, Vladimir M. Trukhan   +7 more
doaj   +1 more source

4-Amino-3-pentadecyl-3H-1,2,4-triazole-3-thiones and 3-pentadecyl-1,3,4-oxadiazole-2(3H)-thione for the preparation of dimeric palladium(II) complexes and their applications in Tsuji-Trost and Mizoroki-Heck reactions

, 2019
The synthesis of palladium complexes derived from 4-amino-3-pentadecyl-3H-1,2,4-triazole-3-thiones and 3-pentadecyl-1,3,4-oxadiazole-2(3H)-thiones are reported.
Manel Chehrouri (6634169), Cristina Moreno-Cabrerizo (6634178), José M. Sansano (2474830), Adil A. Othman (6634172), Samuel Jiménez-Cecilia (6634175)   +4 more
core   +1 more source

Revisiting the Formation Mechanism of 1,3,4-Oxadiazole-2(3H)‑ones from Hydrazonyl Chloride and Carbon Dioxide

, 2018
The reaction mechanism for the synthesis of 1,3,4-oxadiazole-2­(3H)-ones from hydrazonyl chloride and CO2 in the presence of CsF/18-crown-6 and toluene, is revisited via density functional theory computations.
Jorge Barroso (3594497), Fernando Murillo (5365844), Gustavo Ávila (5860646), Sudip Pan (1542133), Gabriel Merino (1413124), María A. Fernández-Herrera (1413115), María G. de los Santos (5860643)   +6 more
core   +1 more source

BIOLOGICALLY ACTIVE OXADIAZOLE [PDF]

, 2015
As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are
Shukla, Chhama, Srivastava, Sanchit
core   +1 more source