Results 81 to 90 of about 12,853,470 (222)

Imidazo[1,2‐b]Pyrazole‐1,2,4‐oxadiazole Linked 1,2,3‐Triazoles: Synthesis, Antibacterial, Biofilm, and In Silico Studies

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A collection of innovative imidazo[1,2‐b]pyrazole–1,2,4‐oxadiazole–1,2,3‐triazole hybrids was conceived via the molecular hybridization of bioactive pharmacophores and produced via a CuAAC methodology. The synthesized compounds exhibited strong antibacterial and antibiofilm properties against gram‐positive bacteria.
Suresh Kumar Murahari, Kavitha Siddoju
wiley   +1 more source

Novel 1,3,4-Oxadiazole-2-carbohydrazides as Prospective Agricultural Antifungal Agents Potentially Targeting Succinate Dehydrogenase

open access: yes, 2019
A novel simple 1,3,4-oxadiazole-2-carbohydrazide was reported to discover low-cost and versatile antifungal agents. Bioassay results suggested that a majority of the designed compounds were extremely bioactive against four types of fungi and two kinds of
Jian-Jun Zhu   +15 more
core   +1 more source

Mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives: use of deuterated analogues in fragmentation pattern studies

open access: yesJournal of the Brazilian Chemical Society, 2004
This paper reported on the study of fragmentation pattern in mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives involving deuterium-labeled analogues to identify some critical fragmentations.
Cerecetto Hugo   +5 more
doaj  

Synthesis of New Three-Component Derivatives of 1, 3, 4-Oxadiazole and Evaluation of Their In Vitro Antibacterial and Antifungal Properties

open access: yesMedical Laboratory Journal, 2021
Background and objectives: Antibiotic resistance is a major public health challenge. The pervasive antibiotic misuse can lead to increased antibiotic resistance.
Nakisa Zarrabi Ahrabi   +2 more
doaj  

Tổng hợp và đánh giá hoạt tính kháng khuẩn của một số dẫn xuất naphthalene-1,3,4-oxadiazole

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2018
1,3,4-Oxadiazole có nhiều hoạt tính sinh học bao gồm kháng khuẩn, kháng nấm, kháng viêm, giảm đau, hạ lipid máu, kháng ung thư, chống co giật, chống đái tháo đường, kháng virus và chống loét.
Nguyễn Thị Cẩm Hồng   +7 more
doaj   +1 more source

A Review of Modern Methods of Synthesis 1, 3, 4-Oxadiazole as a Bioactive Compounds

open access: yesWasit Journal for Pure sciences, 2023
ABSTRACT: Oxadiazole ring is a heterocyclic molecule with an oxygen and two nitrogen atoms spread throughout its five-membered structure. There are four different isomers that have been discovered, Because of their wide applications in a range of sectors, including medications . Some of these biological activity are; anticonvulsant capacity, anticancer
openaire   +2 more sources

Regioselective Oxidative Oligomerization of 2‐Tert‐Butylpyrene Toward Structurally Defined Oligomers and Their Application in Organic Light‐Emitting Diodes

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 36, 24 September 2026.
Treatment of 2‐tert‐butylpyrene with Cu2+ afforded structurally well‐defined pyrene oligomers, up to the 13‐mer. Single‐crystal X‐ray diffraction, spectroscopic analyses, and computational studies were conducted to evaluate the properties of the resulting oligopyrenes.
Md Jadu Mia   +14 more
wiley   +1 more source

Synthesis of Some New Heterocyclic Fused Rings Compounds Based on 5-Aryl-1,3,4-Oxadiazole

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
The work includes synthesis and characterization of some new heterocyclic compounds, as flow: The compound (3) (5-(4-chlorophenyl) -2-hydrazinyl-1,3,4-oxadiazole was synthesized by using two methods; the first method includes the direct reaction between
Zahra Mohammed Abbas   +2 more
doaj  

Strategic integration of 1,2,4-oxadiazole and nitramino-triazole frameworks for high-energy-density materials

open access: yesDefence Technology
Developing high-energy-density materials (HEDMs) with balanced energy and safety performance remains a significant challenge in energetic materials. This study presents the synthesis and systematic characterization of two novel high-performance energetic
Ziyi Xu   +6 more
doaj   +1 more source

Oxadiazolone‐Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II‐Induced Vascular Contraction

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira   +5 more
wiley   +1 more source

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